NOX4 modulates breast cancer progression through cancer cell metabolic reprogramming and CD8+ T cell antitumor activity by Yingying Xiong, Yiming Weng, Shan Zhu, Jian Qin, Jia Feng, Xiaopeng Jing, Chao Luo, Wei Gong, Rui Sun, Min Peng

“…Although NADPH oxidase 4 (NOX4) has been implicated in various oncogenic processes, its exact function in breast cancer progression, metabolic reprogramming, and immune modulation remains unclear.MethodsWe used murine 4T1 and EO771 breast cancer models to generate NOX4 knockout (KO) cell lines via CRISPR/Cas9. …”
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磷脂在蛋白质乳液中的作用研究进展Research progress on the role of phospholipids in protein-based emulsions by 李雪阳1，邹依彤1，涂向辉1，祁冰洁1，刘新2， 杨庆余1，王丽娟1 " LI Xueyang1, ZOU Yitong1, TU Xianghui1, QI Bingjie1, LIU Xin2 , YANG Qingyu1，WANG Lijuan1"

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Predictive markers of rapid disease progression and chemotherapy resistance in triple-negative breast cancer patients following postoperative adjuvant therapy by Tao Ma, Xiao-meng Hao, Hong-dan Chen, Min-hui Zheng, Xiao-geng Chen, Shuang-Long Cai, Jin Zhang

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Corrigendum to “Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon” by Carl-Joe Mehanna, Maamoun Abdul Fattah, Hani Tamim, Mona P. Nasrallah, Raya Zreik, Sandra S. Haddad, Jaafar El-Annan, Samih Raad, Randa S. Haddad, Haytham I. S. Salti

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Multitarget CDK inhibitors roscovitine and UCN‑01 induce apoptosis in colorectal cancer cells by inhibiting cell cycle progression and transcription by Sonal Mohan Manohar, Kalpana Sanjay Joshi

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Research progress of extended care in elderly patients with chronic diseases (老年慢性病患者延续性护理的研究进展) by BI Xiaolu (毕晓露), DENG Ying (邓颖)

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Thermal Mismatch Effect and High-Temperature Tensile Performance Simulation of Hybrid CMC and Superalloy Bolted Joint by Progressive Damage Analysis by Shuyuan Zhao, Jianglong Dong, Chao Lv, Zhengyu Li, Xinyang Sun, Wenjiao Zhang

“…To address this concern, a finite element model embedded with progressive damage analysis was established to simulate the thermostructural behavior and high-temperature tensile performance of single-lap, single-bolt C/SiC composite and superalloy joint, by using the ABAQUS software. …”
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<i>Ginkgo biloba</i> Extract Prescriptions Are Associated with Slower Progression of Dementia Severity—Analysis of Longitudinal Real-World Data by Jens Bohlken, André Hajek, Martin Burkart, Karel Kostev

“…Background/Objectives: Previous research indicates that <i>Ginkgo biloba</i> extract (Gbe) may contribute to slowing down the progression of dementia. This retrospective cohort study analyzed the association between Gbe prescriptions and the progression of dementia severity in a real-world setting. …”
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Research progress of scales for assessment of post-stroke depression (脑卒中后抑郁评估量表的研究进展) by CHEN Shanshan (陈闪闪), GUO Hong (郭红), GONG Shaohua (弓少华), HU Nannan (胡楠楠), ZHANG Ao (张傲)

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A Conserved Di-Lysine Motif in the E2 Transactivation Domain Regulates MmuPV1 Replication and Disease Progression by Jessica Gonzalez, Marsha DeSmet, Elliot J. Androphy

“…Both K113 mutants were able to induce wart formation in vivo, though disease progression appeared to be delayed in the K113Q group. …”
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A rare case of acute respiratory distress syndrome due to chlorine gas inhalation: Rapid progression with favorable ICU outcome by Dung Thai Pham, Bang Ngoc Dao, Dung Tien Nguyen, Ba Van Dang, Dung Tien Le, Hung Manh Do, Loc Tich Hoang, Minh Tuan Ngo, Duong Minh Vu

“…The patient's condition deteriorated rapidly, with symptoms progressing to acute pulmonary edema and severe hypoxemia, requiring immediate transfer to the intensive care unit (ICU). …”
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Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease by Xian Liu, Qin Yu, Hai-Bo Mao, Jing-Bo Hu, Wei-Hua Liu

“…In summary, our findings confirm that Ru/Cur nanodots mitigate the pathological conditions associated with both AKI and its progression to CKD by reducing IR-induced tubular cell injury.…”
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Application and progress of non-invasive imaging in predicting lung invasive non-mucinous adenocarcinoma under the new IASLC grading guidelines by Jinbao Feng, Xiaonan Shao, Jianxiong Gao, Xinyu Ge, Yan Sun, Yunmei Shi, Yuetao Wang, Rong Niu

“…This review outlines the establishment and prognostic efficiency of the new IASLC grading system, highlights the application and latest progress of non-invasive imaging techniques in predicting lung INMA grading, and discusses their role in personalized treatment of lung INMA and future research directions. …”
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The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing <i>AP1S2</i> by B. Zhang, R. Liu, T. Ma, X. Li, Y. Zhao, H. Su, J. Li, Y. Li, H. Jiang, Q. Zhang

“…These results showed that miRNA-211 significantly affected the melanogenesis progress via downregulating <i>AP1S2</i> and advantageously affected the melanin content of Cashmere goat skin.…”
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Effect of a Ketogenic Diet on Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) Progression: A Randomized Controlled Trial by Sakkarin Chirapongsathorn, Wiwit Rintaravitoon, Bhagawat Tangjaturonrasme, Samitti Chotsriluecha, Yanisa Pumsutas, Achariya Kanchanapradith, Sombat Treeprasertsuk

“…However, a ketogenic diet did not reduce steatosis nor worsen MASLD progression. Longer and larger studies are required to determine the long‐term safety and efficacy of the ketogenic diet. …”
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High interstitial fluid pressure enhances USP1-dependent KIF11 protein stability to promote hepatocellular carcinoma progression by Zhengyi Wu, Chao Li, Shouhua Zhang, Liang Sun, Junwen Hu, Bingbing Qiu, Shuiqiu Liu, Yiran Hong, Tianxiang Chen, Kai Wang, Xiangbao Yin, Jinlong Yan

“…Inhibition of USP1 using ML323 significantly reduced KIF11 protein levels and suppressed tumor progression in the mouse model. Conclusion These findings suggest that the HIFP environment fosters HCC progression through USP1-mediated stabilization of KIF11, highlighting USP1 as a potential therapeutic target, especially in patients with portal hypertension.…”
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Exploring effects of a booster workshop on progression and retention of resuscitation skills of residents when added to regular low-dose simulation by Hui-Wen Chen, Hung-Wei Tsai, Yi-Chun Chen, Yu-Jui Chiu, Enoch Yi-No Kang, Yi-Ting Hsu, S. Barry Issenberg, Jen-Chieh Wu

“…This study aims to explore the effects of regular low-dose simulation combined with a booster workshop on the progression and retention of resuscitation skills and teamwork among residents. …”
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Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer by Yuqi Wang, Yunlong Zhang, Min Liu, Yu Liu, Yu Zeng, Wei Zhang, Shuping Wu, Linfei Hu, Xianhui Ruan, Xiangqian Zheng, Ming Gao, Jingzhu Zhao

“…Abstract Programmed cell death (PCD) is a vital biological process that is essential for regulating cell progression and tumor microenvironment. This study aimed to explore the relationship between PCD-related genes expression and prognosis in thyroid cancer (THCA), especially IL20RA, as a potential prognostic marker for THCA. …”
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Research progress of standardized management of pain in chronic wounds (慢性伤口规范化疼痛管理的研究进展) by YUE Lina (岳丽娜), LI Jinghuan (李靖嬛)

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ANRIL regulates retinoblastoma progression via targeting autophagy by miR-328-3p/TSC1/ULK signaling by Yang Yang, Yuezhi Zhang, Yanmei Fu, Shuanglian Li, Xiaolong Yin

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