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Identification of a pancreatic stellate cell gene signature and lncRNA interactions associated with type 2 diabetes progression
Published 2025-01-01“…This research provides insights into PSCs as a modulator in T2D progression, paving the way for innovative treatment strategies.…”
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Progressive Multifocal Liquid Lenses Based on Asymmetric Freeform Surface Structure of Nonuniform Thickness Elastic Membranes with Different Constraints
Published 2019-01-01“…For a progressive multifocal liquid lens with an elastic membrane deformed by liquid pressure, to realize a reasonably power distribution, asymmetric deformation characteristics of the membrane surface are needed. …”
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miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5
Published 2021-01-01“…Our research identified that miR-370-3p promoted breast cancer progression by inhibiting FBLN5 expression and activating the NF-κB signaling pathway. …”
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APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression
Published 2025-01-01“…Despite this, effectively treating metastatic ccRCC remains a significant challenge, necessitating a more profound comprehension of the underlying molecular mechanisms governing its progression. Here, we unveil that the enhanced expression of the RNA‐binding protein DNA dC → dU‐editing enzyme APOBEC‐3C (APOBEC3C; also known as A3C) in ccRCC tissue and ccRCC‐derived cell lines serves as a catalyst for tumor growth by amplifying nuclear factor‐kappa B (NF‐κB) activity. …”
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Progressive Improvement of T-Scores in Men with Osteoporosis and Subnormal Serum Testosterone Levels upon Treatment with Testosterone over Six Years
Published 2014-01-01“…Over the 6 year period there was a significant and progressive improvement of the T-scores in these men. …”
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TP53 Mutation Predicts Worse Survival and Earlier Local Progression in Patients with Hepatocellular Carcinoma Treated with Transarterial Embolization
Published 2025-01-01“…The time to progression with death or the last patient contact without progression as competing risks were used to obtain a cumulative incidence function, and the association with TP53 status was evaluated using the Gray test. …”
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Evaluation of comorbidity burden on disease progression and mortality in patients with interstitial pneumonia with autoimmune features: A retrospective cohort study.
Published 2025-01-01“…Both CCI and RDCI were associated with shorter time to lung disease progression and lung transplant/death in unadjusted analyses. …”
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Research progresses and hotspots on glucose metabolic reprogramming in breast cancer: a bibliometric analysis over the past two decades
Published 2025-01-01“…Keyword analysis suggested that the mechanisms of glucose metabolism reprogramming in BC and related therapeutic strategies were the research hotspots.ConclusionThis study, for the first time, elucidated the progresses and hotspots of in the research on glucose metabolism reprogramming in BC, highlighting its potential role in treating BC. …”
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Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits
Published 2024-06-01“…Results CytoTDP fish have early larval phenotypes resembling clinical features of ALS such as progressive motor defects, neurodegeneration and muscle atrophy. …”
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UGCG promotes chemoresistance and breast cancer progression via NF-κB and Wnt/β-catenin pathway activation
Published 2025-02-01“…The role of UGCG in the malignant progression and chemoresistance of TNBC was assessed through various functional assays. …”
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Analysis of Indicators for Assessing the Risk of Progression from PACS to APAC and the Degree of Intraocular Pressure Elevation in APAC Using AS-OCT
Published 2024-01-01“…IA may serve as a predictive indicator of the progression of eyes from PAC or APAC. A significant negative correlation was found between intraocular pressure and IV during APAC attacks. …”
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