A comprehensive transcriptional reference for severity and progression in spinal cord injury reveals novel translational biomarker genes by Rubén Grillo-Risco, Marta R. Hidalgo, Beatriz Martínez-Rojas, Victoria Moreno-Manzano, Francisco García-García

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METTL14 modulates the progression and ferroptosis of colitis by regulating the stability of m6A-modified GPX4 by Yuhua Chen, Weicong Fan, Ying Lyu, Jingsheng Liao, Ying Zhou

“…UC development and progression were closely associated with epigenetic modifications. …”
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Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma by Yue Dai, Hongchen Li, Shiyin Fan, Kai Wang, Ziyi Cui, Xinyu Zhao, Xue Sun, Mingen Lin, Jiaxi Li, Yi Gao, Ziyin Tian, Hui Yang, Bingbing Zha, Lei Lv, Yanping Xu

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PD‐1+CD8+ T Cell‐Mediated Hepatocyte Pyroptosis Promotes Progression of Murine Autoimmune Liver Disease by Jie Long, Si‐Yu Yang, Zhen‐Hua Bian, Hao‐Xian Zhu, Min Ma, Xiao‐Qing Wang, Liang Li, Weici Zhang, Ying Han, M. Eric Gershwin, Zhe‐Xiong Lian, Zhi‐Bin Zhao

“…GSDMD‐mediated pyroptosis is found to be aberrantly activated in the livers of model mice, and treatment with a GSDMD‐specific inhibitor significantly inhibits disease progression. In vitro experiments reveal that PD‐1+CD8+ T cells can induce the pyroptosis of hepatocytes through elevated production of granzyme B and perforin‐1. …”
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The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression by Qinxue Ni, Hong Yang, Hang Rao, Liyong Zhang, Mengyuan Xiong, Xiao Han, Boshao Deng, Lulu Wang, Jian Chen, Yan Shi

“…The impact of the complement system on iron metabolism and its role in gastric cancer progression is an area warranting further investigation. …”
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Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism by Xiao-Qing Song, Tian-Jian Yu, Yang Ou-Yang, Jia-Han Ding, Yi-Zhou Jiang, Zhi-Ming Shao, Yi Xiao

“…The upregulation of SREBP1 enhances the expression of lipid biosynthesis genes, ultimately facilitating the progression of TNBC. Clinically, pharmacological inhibition of the FLAD1/LSD1/SREBP1 axis effectively suppresses FLAD1-induced tumor progression. …”
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Guided Bilateral Transcanine Implant Placement and Implant-Supported Oral Rehabilitation in a Patient with Progressive Systemic Scleroderma by Igor Smojver, Ivan Katalinić, Marko Vuletić, Luka Stojić, Dražena Gerbl, Dragana Gabrić

“…The aim of this report was to add a new case of a transimpacted tooth dental implant placement to the existing international literature and to share our experience of transcanine implantation in the maxilla followed by implant prosthodontic rehabilitation of a patient with progressive systemic scleroderma. A 55-year-old woman attended our office for oral cavity assessment and treatment planning for complete oral rehabilitation. …”
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circ_0052184 Promotes Colorectal Cancer Progression via Targeting miR-604/HOXA9 Axis by Yandong Huang, Qinyang Bai, Zhanlong Wang, Hongbo Yu, Yanru Li, Hao Lu, Huimin Kang, Xuewei Shi, Kai Feng

“…The mortality rate of colorectal cancer (CRC) ranks second. circRNAs are abnormal expression in some diseases, and their dysregulation is associated with cancer progression. Recent studies have shown that the malignant progression of colorectal cancer is inseparable from the abnormal expression of circRNAs. …”
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Very low urinary marinobufagenin excretion reflects a high risk of disease progression in non-advanced CKD by Davide Bolignano, Davide Bolignano, Marta Greco, Marta Greco, Loredana Tripodi, Mario D’Agostino, Paola Cianfrone, Roberta Misiti, Roberta Misiti, Sara Pugliese, Mariateresa Zicarelli, Michela Musolino, Michela Musolino, Daniela Patrizia Foti, Daniela Patrizia Foti, Michele Andreucci, Michele Andreucci, Giuseppe Coppolino, Giuseppe Coppolino

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Clinical course and potential associated factors of progressive calcinosis cutis in early systemic sclerosis: a cohort study by Vassana Kanjanajarurat, Prathana Chowchuen, Chingching Foocharoen, Punthip Thammaroj

“…Background Calcinosis cutis of hands can progress and impair hand function in systemic sclerosis (SSc). …”
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Healthcare Providers’ Knowledge and Current Practice of Pain Assessment and Management: How Much Progress Have We Made? by Khawla Nuseir, Manal Kassab, Basima Almomani

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Enhancing Return to Alpine Skiing: Integrating Perceptual-Motor-Cognitive Considerations in Testing and Progressions: A Clinical Commentary by Conor Smith, Dustin R. Grooms, Helen Bradley

“…The purpose of this clinical commentary is to address the perceptual-motor-cognitive demands specific to alpine skiing, evaluate RTS testing for skiers, and propose updated standards for testing and return to snow progressions that incorporate these considerations. # Level of Evidence 5…”
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Recent Progress in Enzyme Immobilization to Metal–Organic Frameworks to Enhance the CO₂ Conversion Efficiency by Yunhan Cao, Pengyan Yang, Rui Zhao, Fenghuan Wang

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Disseminated Mycobacterium chelonae Infection Presenting as Progressive Multifocal Osteomyelitis: Report of Two Cases and a Review of the Literature by David A Oelberg, Jack Mendelson, Mark A Miller, Andre Dascal

“…The infections were indolent and marked by progressive bony destruction. These cases and a review of the literature are presented.…”
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Research progress on moxibustion in the treatment of urinary incontinence in the elderly (艾灸治疗老年尿失禁研究进展) by JIN Wenli (靳文丽), ZHANG Yuanchun (张元春), HAN Jingjing (韩京晶), LIU Jining (刘继宁), FAN Hongxue (范红雪)

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Appropriating Epistemic Norms of Science through Sustained Practice with Argumentation: Can It Happen? A Learning Progressions Perspective by Mehmet Aydeniz, Kader Bilican

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Application Progress of Transcranial Direct Current Stimulation Combined with Limb Therapy in Rehabilitation of Lower Limbs after Stroke by CHEN Hanbo, LU Xiao, ZHENG Wenhua, GUO Yongliang, YAN Tiebin

“…This article reviews the application progress of tDCS with different treatment parameters combined with different lower limb rehabilitation techniques and different cooperative treatment sequence in stroke, and discusses the factors which affect the effect of cooperative treatment and the possible effective cooperative treatment mode, in order to provide new ideas for the treatment of lower limb dysfunction after stroke.…”
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Evolution of Orofacial Symptoms and Disease Progression in Idiopathic Parkinson’s Disease: Longitudinal Data from the Jönköping Parkinson Registry by Seyed-Mohammad Fereshtehnejad, Örjan Skogar, Johan Lökk

“…Individuals with more severe orofacial burden at baseline progressed faster to more advanced stages.…”
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A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression by Qiuyang Wang, Kai Feng, Guangsheng Wan, Wei Liao, Jing Jin, Peng Wang, Xiaolian Sun, Weijun Wang, Qing Jiang

“…This study reveals that si-Fe-HPP, with its ROS-responsive and RNAi abilities, can significantly protect chondrocytes and attenuate OA progression, providing novel insights and directions for the development of therapeutic materials for OA treatment. …”
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Association of Immunosuppression with DR6 Expression during the Development and Progression of Spontaneous Ovarian Cancer in Laying Hen Model by Sa’Rah McNeal, Pincas Bitterman, Janice M. Bahr, Seby L. Edassery, Jacques S. Abramowicz, Sanjib Basu, Animesh Barua

“…Immune functions are important to prevent OVCA progression and recurrence. The mechanism of immunosuppression, a hallmark of tumor progression, is not well understood. …”
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