Insulin-Like Growth Factor and Epidermal Growth Factor Signaling in Breast Cancer Cell Growth: Focus on Endocrine Resistant Disease by Kallirroi Voudouri, Aikaterini Berdiaki, Maria Tzardi, George N. Tzanakakis, Dragana Nikitovic

“…The IGF-I and EGF downstream signaling pathways are closely involved in the process of progression to therapy resistant disease. Modifications in the bioavailability of these growth factors contribute critically to disease progression. …”
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Understanding the phases and objectives of the career development process in the context of successful career management by Ilić Đurđijana

“…The basis of a quality organization consists of reliable employees who are satisfied with their work, ready to learn and progress, and thus continuously bring profit and progress to themselves and the organization. …”
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Bimelic Hirayama Disease: Clinical Dilemma Solved by Imaging by Shalabh Jain, Siddharth Yadav, Swarna Gupta, Ritu Gupta

“…It is characterized by progressive muscular weakness and atrophy of unilateral or asymmetrically bilateral distal upper limbs. …”
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The Emerging Role of GC-MSCs in the Gastric Cancer Microenvironment: From Tumor to Tumor Immunity by Zhaoji Pan, Yiqing Tian, Guoping Niu, Chengsong Cao

“…Mesenchymal stem cells (MSCs) have been declared to not only participate in wound repair but also affect tumor progression. Tumor-associated MSCs, directly existing in the tumor microenvironment, play a critical role in tumor initiation, progression, and development. …”
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The possible therapeutic role of advanced glycation end-product inhibitors in ischemic stroke by Nada H. Aljarba, Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Mustafa M. Shokr, Marios Papadakis, Athanasios Alexiou, Mubarak Alruwaili, Mohammed Alrouji, Mohammed S. Alshammari, Gaber El-Saber Batiha

“…AGEs promote the generation of reactive oxygen species that induce the release of pro-inflammatory cytokines, and alter the intracellular signaling leading to progressive biochemical and metabolic derangements. …”
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Liver Infarction in a Patient with HELLP and Probable Anti-phospholipid Syndrome by Cihan Kaya, Hüseyin Cengiz, Murat Ekin, Ammar Kanawati, Levent Yaşar

“… The aim of this report is to make an awareness about hepatic infarction in those patients with progressively elevating liver enzymes and anti-phospholipid syndrome. …”
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Animal models for transplant immunology: bridging bench to bedside by Minseok Kang, Hwon Kyum Park, Kyeong Sik Kim, Dongho Choi

“…The progress of transplantation has been propelled forward by animal experiments. …”
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Molecular Pathogenesis of Cholangiocarcinoma by G. Fava, I. Lorenzini

“…This Paper describes the scientific progresses made in the last years in defining the molecular pathways implicated in the generation of this devastating disease.…”
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An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature by Yiqiao Wang, Andre Le, Dina El Demellawy, Mary Shago, Michael Odell, Stephanie Johnson-Obaseki

“…Divided into non- and aggressive subtypes, the aggressive subtype is relatively rare and can occasionally progress rapidly, resulting in significant morbidity. …”
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Features of testing as control devices and estimations of educational achievements of students by Irina N. Bulanova

“…In the article one of control devices and estimation of progress of students - testing is considered. Features of main types of test tasks are described. …”
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Interleukin IL1a and IL6 gene polymorphism: search for association with APOE genotype and clinical course of sporadic Alzheimer’s disease by G. Pšemeneckienė, K. Petrikonis, D. Rastenytė

“…No significant differences of genotype frequencies in rapidly progressing AD compared to slowly progressing AD were revealed (p (IL1A -889C>T)=0.638; p (IL6 -174G>C)=0.118). …”
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Elucidating epigenetic landscape of gastric premalignant lesions through genome‐wide mapping of 5‐hydroxymethylcytosines: A 12‐year median follow‐up study by Zhongguang Luo, Wenshuai Li, Wanwei Zheng, Yixiang Shi, Maolin Ye, Xiangyu Guo, Kaiyi Fu, Changsheng Yan, Bowen Wang, Bin Lv, Shaocong Mo, Hongyang Zhang, Jun Zhang, Chuan He, Feifei Luo, Wei Zhang, Jie Liu

“…Genome‐wide mapping of 5hmC in gastric premalignant lesions from a subset of individuals was performed using the 5hmC‐Seal assay, including 21 samples that progressed to GAC during follow‐up and 48 non‐progressed age‐ and sex‐matched controls. …”
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Host Factors in the Natural History of Chronic Hepatitis B: Role of Genetic Determinants by null Turyadi, Billy Witanto, Korri E. El-Khobar, M. Luthfi Parewangi, M. Rezki Rasyak, Dhita P. Wibowo, Meta D. Thedja, Irawan Yusuf, Muh. Nasrum Massi, Ilhamjaya Patellongi, Din Syafruddin, David H. Muljono

“…Genetic polymorphisms of several inflammatory cytokines, including TNF-α and IL-10, have been associated with chronic hepatitis B (CHB) progression, although with contradicting results. CHB progression can be categorized into four phases, immune tolerance (IT), immune clearance (IC), low/no replicative (LR), and e-negative hepatitis (ENH), with HBeAg seroconversion as an important milestone. …”
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PAX6 enhances Nanog expression by inhibiting NOTCH signaling to promote malignant properties in small cell lung cancer cells by Xiao-Fang Guo, Ling-Ling Wang, Fei-Meng Zheng, He-Ping Li

“…Here, we find that PAX6 overexpression promotes SCLC cell proliferation and cell cycle progression, while downregulation of PAX6 expression suppresses SCLC cell proliferation and cell cycle progression. …”
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Roles of Copper Transport Systems Members in Breast Cancer by Yichang Chen, Chen Li, Mengxin Li, Bing Han

“…ABSTRACT Background The occurrence and progression of breast cancer are closely linked to copper ion homeostasis. …”
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Use of multipotent mesenchymal stromal cells as part of bone marrow concentrate in the complex treatment of aseptic necrosis of the femoral head: a systematic review by Alina R. Zakirova, Alexander N. Torgashin, Svetlana S. Rodionova

“…In the main group, where mesenchymal stromal cells were used, X-ray progression to the next stage occurred in 31.25% of cases and the need for endoprosthetics was 30.6%; in the comparison group, the progression occurred in 68.75% of cases and the need for endoprosthetics was 69.4 %. …”
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Host genetics and gut microbiota influence lipid metabolism and inflammation: potential implications for ALS pathophysiology in SOD1G93A mice by Elena Niccolai, Leandro Di Gloria, Maria Chiara Trolese, Paola Fabbrizio, Simone Baldi, Giulia Nannini, Cassandra Margotta, Claudia Nastasi, Matteo Ramazzotti, Gianluca Bartolucci, Caterina Bendotti, Giovanni Nardo, Amedeo Amedei

“…Abstract Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder characterized by the progressive loss of motor neurons, with genetic and environmental factors contributing to its complex pathogenesis. …”
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The Effect of Steep Trendelenburg Positioning on Retinal Structure and Function during Robotic-Assisted Laparoscopic Procedures by Kazuyuki Hirooka, Kaori Ukegawa, Eri Nitta, Nobufumi Ueda, Yushi Hayashida, Hiromi Hirama, Rikiya Taoka, Yuma Sakura, Mari Yamasaki, Hiroyuki Tsunemori, Mikio Sugimoto, Yoshiyuki Kakehi

“…RNFL thickness progression and visual field progression were evaluated by event analysis. …”
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Chronic Myeloid Leukemia: Part II—Cost of Care Among Patients in Advanced Phases or Later Lines of Therapy in Chronic Phase in the United States from a Commercial Perspective by Ehab L. Atallah, Rodrigo Maegawa, Dominick Latremouille-Viau, Carmine Rossi, Annie Guérin

“…Moreover, even with TKIs, some patients progress to accelerated phase/blast crisis (AP/BC), which is associated with particularly poor clinical outcomes. …”
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Introducing an ensemble method for the early detection of Alzheimer's disease through the analysis of PET scan images by Arezoo Borji, Taha-Hossein Hejazi, Abbas Seifi

“…Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. …”
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