The Role of Indoxyl Sulfate in Exacerbating Colorectal Cancer During Chronic Kidney Disease Progression: Insights into the Akt/β-Catenin/c-Myc and AhR/c-Myc Pathways in HCT-116 Colorectal Cancer Cells by Yu Ichisaka, Chihiro Takei, Kazuma Naito, Manami Higa, Shozo Yano, Toshimitsu Niwa, Hidehisa Shimizu

“…Our previous study demonstrated that indoxyl sulfate, a uremic toxin whose concentration increases with CKD progression, exacerbates CRC through activation of the AhR and Akt pathways. …”
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Isolated Central Nervous System Infiltrated and Progressed to Acute Myeloid Leukemia from Chronic Myeloid Leukemia with e1a3 BCR-ABL1 Transcript: A Rare Case Report and Literature Review by Qiang X, Wen Q, Li J, Chen S, Tao T, Zhang H, Wang P, Peng X, Feng Y, Zhang X

“…Subsequent bone marrow analysis and flow cytometry detection of cerebrospinal fluid indicated that the patient had entered the blast phase, progressing to acute myeloid leukemia (AML). Treatment was switched to the third-generation TKI olverembatinib, combined with chemotherapy, followed by allogeneic hematopoietic stem cell transplantation. …”
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Transition from hypothyroidism to Graves’ disease, development of thyroid eye disease, progression to optic neuropathy after inpatient pulse therapy, and long-term administration of outpatient pulse therapy: a case report with review of literature by Koichiro Mizuochi, Yuji Hiromatsu, Yui Nakamura, Aya Sonezaki, Ayaka Adachi, Tamotsu Kato, Nobuhiko Wada, Tomohiro Kurose, Shiho Watanabe

“…After three cycles of daily methylprednisolone pulse therapy, her condition progressed to dysthyroid optic neuropathy with decreased visual acuity in both eyes. …”
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Application progress of Traditional Chinese Medicine nursing technology in pain control after total knee arthroplasty (中医护理技术在膝关节置换术后疼痛干预中的应用进展) by LIU Fei (柳菲), YAN Qiuyan (闫秋艳)

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Association of Cutaneous Immune-related Adverse Events with Overall Survival and Progression-free Survival in Oncology Patients Receiving Immune Checkpoint Inhibitors: A Prospective Study of 189 Patients in a Spanish Tertiary Care Hospital by Gloria Juan-Carpena, Natividad Martínez Banaclocha, Juan Carlos Palazón Cabanes, Maria Niveiro-de Jaime, Isabel Betlloch Mas, Mar Blanes-Martínez

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Medical (Mal)Practice and the Illusion of Progress in Edward Berdoe’s St Bernard’s: The Romance of a Medical Student and Leonard Graham’s The Professor’s Wife: A Genealogical Analysis of Epistemological and Ethical Arguments in Two Late-Victorian Novels by Adrian Tait

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Research progress of exercise rehabilitation in patients undergoing percutaneous coronary intervention for acute myocardial infarction (急性心肌梗死患者经皮冠状动脉介入术后运动康复的研究进展) by JIA Hongwei (贾红薇), XING Zheng (邢政), DONG Yujie (董玉洁), SHAN Li (单立), LIU Yanjie (刘艳杰), WANG Jing (王晶), YI jiaxin (益嘉欣), YANG Lin (杨林)

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Shared prognostic information in amyotrophic lateral sclerosis – systematic assessment of the patients’ perception of neurofilament light chain and the ALS functional rating scale... by Lukas Maximilian Möhwald, André Maier, Torsten Grehl, Ute Weyen, Patrick Weydt, René Günther, Paul Lingor, Bettina Göricke, Susanne Petri, Julian Grosskreutz, Matthias Boentert, Isabell Cordts, Jochen H. Weishaupt, Johannes Dorst, Christoph Münch, Thomas Meyer, Petra Baum

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Personal Development Planning of the UK Students: Implementation Models by N. Yu. Shaposhnikova

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MicroRNA-140-5p inhibits cellular proliferation, migration and invasion by downregulating AKT/STAT3/NF-κB pathway in breast carcinoma cells by Hou Lingli, Liu Qi, Zhao Ying, Yang Hongwei, Meng Qingying, Yu Fei

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Case report: Atypical young case of MV1 Creutzfeldt-Jakob disease with unusually long survival by Lucie Yeongran Ahn, Mark L. Cohen, Mark L. Cohen, Ignazio Cali, Ignazio Cali, Tia Russell, Jessica Ludwig, Xun Jia, Alberto Bizzi, Lawrence B. Schonberger, Ryan A. Maddox, Rohini Paul, Tania C. Ghazarian, Jaspreet Garcha, Mostafa Hammoudi, Brian Stephen Appleby, Brian Stephen Appleby, Brian Stephen Appleby, Brian Stephen Appleby

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Rechallenge therapy versus tyrosine kinase inhibitor (TKI) for advanced metastatic colorectal cancer: a retrospective study by Chenming Liu, Jintao Chen, Yuxing Liu

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Clinical characteristics, therapeutics, and treatment outcomes of adult patients with anti-melanoma differentiation-associated gene 5 dermatomyositis: A single-center experience fr... by Shivraj Padiyar, Aswin M Nair, Bijesh Yadav, Prathyusha Manikuppam, Jha Avanish, Abhilasha Arvind Manwatkar, John Mathew

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Bibliometric Analysis of Optimal Scheme Selection for Water Conservancy Projects by ZHANG Boyang

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Social aspects of the development of family taxation in the Russian Federation by T. V. Zvereva

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Demographic modeling of transient amplifying cell population growth by Shinji Nakaoka, Hisashi Inaba

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Expression and prognostic significance of the m6A RNA methylation regulator HNRNPC in HNSCC by Yulin Zhang, Yixu Wang, Jilin Peng, Kun Zhao, Ling Li, Yuan Zhang, Ziyu Zhai, Sijie Yuan, Shichao Li, Shichao Li, Shichao Li, Fanglei Ye, Le Wang

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Ocular adnexal lymphoma – A single-center observational study of survival outcomes by Karuvel Kannan Saraswathi, Pragya Saini, Radhakrishnan Santhi, Veerappan Muthukkaruppan, Ayyasamy Vanniarajan, Usha Kim

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East and West: global technological confrontation by S. S. Belikova, A. V. Belikov

Subjects: “…scientific and technological progress…”
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INNOVATIVE PROCESSES IN AIC: PROBLEMS AND PERMITS by A. Kamalova, R. Tagibova, M. Kardashova, A. Uzarhanova

Subjects: “…scientifically-technical progress…”
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