Acquisition of innate B cell properties and generation of autoreactive IgA antibodies by follicular B cells during homeostatic proliferation by Laura Kampe, Laura Kampe, Christian Melcher, Christian Melcher, Katrin Westphal, Katrin Westphal, Korbinian Brand, Niko Föger, Niko Föger, Kyeong-Hee Lee, Kyeong-Hee Lee

“…During homeostatic proliferation, B cells undergo antigen-independent clonal expansion and differentiation into antibody-producing plasma cells (PCs). …”
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Risk factors for multidrug resistance in pulmonary tuberculosis patients with diabetes mellitus by Lianpeng Wu, Lianpeng Wu, Na Chen, Na Chen, Dandan Xia, Dandan Xia, Xiangao Jiang, Xiangao Jiang

“…Significant independent predictors of MDR included a history of TB treatment, smoking, and elevated hemoglobin A1c (HbA1c) levels. …”
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Piloting creative engagement strategies to explore themes of parenthood with fathers by Iryna Culpin, Iryna Culpin, Catherine Lamont-Robinson, Mark Billington, Matthew James, James Prewett, Gareth Ward, Mireia Bes Garcia, Giovanni Biglino, Giovanni Biglino

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Vaping – A Beneficial Alternative to Traditional Cigarettes or an Unexplored Danger? by Paulina Błasiak, Aleksandra Ślusarska, Patryk Mikołajec, Barbara Bilecka, Jolanta Mędyk, Małgorzata Wirkijowska, Jakub Wirkijowski, Yauheniya Patarocha, Michał Rogulski, Ruslan Huk

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A New Four‐Component L*‐Dependent Model for Radial Diffusion Based on Solar Wind and Magnetospheric Drivers of ULF Waves by Kyle R. Murphy, Jasmine Sandhu, I. Jonathan Rae, Thomas Daggitt, Sarah Glauert, Richard B. Horne, Clare E. J. Watt, Sarah Bentley, Adam Kellerman, Louis Ozeke, Alexa J. Halford, Sheng Tian, Aaron Breneman, Leonid Olifer, Ian R. Mann, Vassilis Angelopoulos, John Wygant

“…The new models use L∗ as it accounts for adiabatic changes due to the dynamic magnetic field coupled with an optimized set of four components of solar wind and geomagnetic activity, Bz, V, Pdyn, and Sym−H, as independent variables (inputs). These independent variables are known drivers of ULF waves and offer the ability to calculate diffusion coefficients at a higher cadence then existing models based on Kp. …”
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Role of the two-component system AmgRS in early resistance of Pseudomonas aeruginosa to cinnamaldehyde by Eline Dubois, Vladimir Spasovski, Patrick Plésiat, Catherine Llanes

“…AmgRS activates MexAB-OprM production, independent of repressors MexR and NalD. In addition to the essential role played by the NalC-ArmR pathway in this adaptive process, AmgRS is critical for the survival of P. aeruginosa challenged with CNA. …”
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Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis by Tianmin Huang, Huixian Jiang, Ganling Tang, Jingyi Li, Xiaoman Huang, Zhenguang Huang, Hongliang Zhang

“…The proportions of response rate (RR) (50% fall in transfusion need in transfusion-dependent β-thalassemia patients, or 1 g/dL elevate in hemoglobin (Hb) levels in transfusion-independent β-thalassemia patients) and good RR (transfusion-free in transfusion-dependent β-thalassemia patients or 2 g/dL elevate in Hb levels in transfusion-independent β-thalassemia patients) were utilized to evaluate the effect size (ES). …”
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Evaluating the Mechanisms of Improved Glucose Homeostasis after Bariatric Surgery in Ossabaw Miniature Swine by Jonathan G. Sham, Vlad V. Simianu, Andrew S. Wright, Skye D. Stewart, Mouhamad Alloosh, Michael Sturek, David E. Cummings, David R. Flum

“…Roux-en-Y gastric bypass (RYGB) is the most common bariatric operation; however, the mechanism underlying the profound weight-independent effects on glucose homeostasis remains unclear. …”
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Promoting critical reading instruction in higher education: a three-step training scheme facilitated by using corpus technology by Yang Jing, Mei Fang

“…The results indicate a positive response to the CBLP, with students’ independent exploration task contributing to improved critical reading and thinking skills. …”
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BMI trajectories are associated with NAFLD and advanced fibrosis via aging-inflammation mediation by Haiyang Peng, Zhibo Zhao, Jianping Gong, Kun He

“…Aging-inflammation may represent a distinct mechanism of sustained obesity to NAFLD, independent of IR.…”
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Acute Coronary Syndromes and Nonalcoholic Fatty Liver Disease: “Un Affaire de Coeur” by Abdulrahman Ismaiel, Stefan-Lucian Popa, Dan L. Dumitrascu

“…Eleven studies evaluated whether NAFLD is an independent risk factor for developing ACS with conflicting results, of which eight studies demonstrated a significant association between NAFLD and ACS, mainly in Asian populations, while three reported a lack of an independent association. …”
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Qualitative Discrimination of Intact Tobacco Leaves Based on Near-Infrared Technology by Mengyao Lu, Qiang Zhou, Tian’en Chen, Junhui Li, Shuwen Jiang, Qin Gao, Cong Wang, Dong Chen

“…The results show that the position-GV discrimination model constructed using independent spectra and the DPLS algorithm and the grade discrimination model constructed using independent spectra and Fisher’s algorithm achieve optimal results with intact leaf NIR wavenumbers from 5006–8988 cm−1 and the first-derivative and standard normal variate transformation preprocessing method. …”
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Construction of a predictive model for the risk of aspiration in enteral nutrition patients in ICU by CHEN Yue, ZHANG Hui, GUAN Chun, HU Fasheng

“…The Random forest model ranked the importance of the independent factors, and the predictive models were visualized using Nomogram.Results A total of 500 patients were included and aspiration occurred in 285 patients, with the incidence of aspiration of 57% in enteral nutrition patients in the ICU. …”
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High-throughput analysis of microbiomes in a meat processing facility: are food processing facilities an establishment niche for persisting bacterial communities? by Zhaohui S. Xu, Vi D. Pham, Xianqin Yang, Michael G. Gänzle

“…Conclusions Culture-dependent isolation, complemented by culture-independent analyses, is essential to fully uncover the microbial diversity in food processing facilities. …”
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A qualitative exploration of the enablers of and barriers to conformance with antibiotic withdrawal periods on smallholding, peri-urban pig farms in Kiambu County, Kenya. by Claire Scott, Nicholas Bor, Kristen K Reyher, Alex J Tasker, Henry Buller, Irene Bueno, Lian F Thomas

“…We also explored farmers' engagement with antibiotic withdrawal periods by visiting thirteen pig farms (supplying one of two local independent abattoirs) weekly for one month in order to capture instances of antibiotic use. …”
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Epidemiology of paediatric intensive care unit admissions, deaths and organ donation candidacy: A single-centre audit by John Zhong Heng Low, Joel Kian Boon Lim, Herng Lee Tan, Rudimar Martinez Fernandez, Samsudin Bin Nordin, Yee Hui Mok, Judith Ju-Ming Wong

“…Multivariable regression was performed to identify independent risk factors for mortality. Organ donation candidacy was evaluated by an independent team based on the criteria by Singapore’s National Organ Transplant Unit. …”
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The Efficacy of Clinical Tests to Diagnose Evaporative Dry Eye Disease Related to Meibomian Gland Dysfunction by Jerry R. Paugh, Tiffany Nguyen, Alan Sasai, Elaine Chen, Melinda Thomas De Jesus, Justin Kwan, Andrew Loc Nguyen, Marjan Farid, Sumit Garg, James V. Jester

“…To determine the efficacy of widely available subtype clinical tests to characterize evaporative dry eye disease (EDED) related to meibomian gland dysfunction (MGD) compared to normal and to validate those clinical cut points in an independent sample. Methods. A diagnostic accuracy study (52 subjects), an investigator-masked study, was followed by a larger independent sample (364 subjects) analysis to confirm efficacy in normal and EDED subjects. …”
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The change of inflammatory markers may predict long-term major adverse cardiovascular events in elderly patients with coronary heart disease: a retrospective cohort study by Li He, Sisi Chen, Xuan Zhu, Fang He

“…The logistic regression analysis found that MHR is independent risk factors for MACE (OR = 6.048, 95% CI 1.224–1.941, p = 0.002). …”
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Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy by Nicholas J. Schnicker, Zhen Xu, Mohammad Amir, Lokesh Gakhar, Chou-Long Huang

“…To understand the FGFR/FGF23-independent pleiotropic functions of sKLA, we investigated biophysical properties and structure of apo-sKLA. …”
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Predictor’s of Mortality in Patients with Aneurysmal Subarachnoid Haemorrhage and Reebleding by Dannys Rivero Rodríguez, Claudio Scherle Matamoros, Leda Fernández Cúe, Jose Luis Miranda Hernández, Yanelis Pernas Sánchez, Jesús Pérez Nellar

“…Demographic, clinical, and radiological variables were examined in logistic regression to evaluate independent factors for increasing the risk of death. …”
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