Repurposing the prostaglandin analogue treprostinil and the calcium-sensing receptor modulator cinacalcet to revive cord blood as an alternate source of hematopoietic stem and prog... by Michaela Prchal-Murphy, Julia Zehenter, Marlene Fischer, Anita Pirabe, Madeleine Themanns, Behnaz Afrashteh, Eva Maria Putz, Karoline Kollmann, José Basílio, José Basílio, Manuel Salzmann, Wolfgang Strohmaier, Günther Krumpl, Alex Farr, Veronika Sexl, Michael Freissmuth, Eva Zebedin-Brandl

“…ObjectiveThe expanding field of hematopoietic cell transplantation (HCT) for non-malignant diseases, including those amenable to gene therapy or gene editing, faces challenges due to limited donor availability and the toxicity associated with cell collection methods. …”
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Out-of-Pocket Expenditure (OOPE) on Selected Surgeries in the Obstetrics and Gynaecology Department incurred by Ayushman Bharat Pradhan Mantri Jan Arogya  Yojana (AB-PMJAY), Privat... by Dr. Kumar Sumit, Reena Verma, Prajwal Salins, Helmut Brand, Siddhartha Sankar Acharya, Sagarika Kamath, rajesh kamath, Dr. Vidya Prabhu

“…Though private health insurance reduced OOPE compared to uninsured patients under private health insurance still faced significant financial burden. Variations existed in minimum and maximum OOPE and percentage of OOPE across different private insurances. …”
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Poor sleep quality remains a major challenge among tertiary education students in Ghana: A cross-sectional study in a Ghanaian University by David Larbi Simpong, Ansumana Bockarie, Akosua Bema Kumah, Alex Bismark Atta-Owusu, Mordecai Eshun, Bernice Akua Frimpong, Beatrice Bachella, George Nkrumah Osei

“…Despite the recognized importance of good sleep for students, there is a need for a deeper understanding of the sleep problems faced by university students to inform effective campus support services and interventions. …”
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Challenges in diagnosing polyethylene glycol and polysorbate 80 allergies: implications for allergic reactions in COVID-19 mRNA vaccination program: experience from Qatar by Sami Aqel, Sherin Thalappil, Asaad Imameldin, Dalal Mudawi, Muna Al Maslamani, Abdullatif Al-Khal, Hassan Mobayed, Maryam Ali Al-Nesf, Tayseer Ibrahim

“…IntroductionCOVID-19 vaccination has been a key intervention in reducing the severity of symptoms; however, concerns about vaccine safety, particularly regarding allergic reactions, arose early on. Healthcare workers faced the challenge of addressing these concerns to ensure safe vaccine administration. …”
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O multiculturalismo e as divergências teóricas no debate multicultural by Willian Martini

“…ABSTRACT Within the debates on multiculturalism, we have a fairly wide variety of lines of thought and very different proposals offering solutions to certain problems faced by several cultures. There are many groups trying to maintain their values and practices within a global reality in which peoples’ actions and thoughts are homogenized. …”
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Social disconnectedness, subsequent medical conditions, and, the role of pre-existing mental disorders: a population-based cohort study by L. M. Laustsen, M. Lasgaard, N. C. Momen, D. Chen, J. L. Gradus, M. S. Grønkjær, M. M. Jensen, O. Plana-Ripoll

“…Conclusions This study advances our knowledge of the risk of medical conditions faced by individuals who are socially disconnected. …”
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Protocol for Home-Based Solution for Remote Atrial Fibrillation Screening to Prevent Recurrence Stroke (HUA-TUO AF Trial): a randomised controlled trial by Jing Tan, Yan Liang, Yong Liu, Wei Jiang, Duo Huang, Ning Tan, Chung-Wah Siu, Jo Jo Hai, Xiaoyu Huang, Jianfeng Ye, Ji-yan Chen, Chun Ka Wong, Mi Zhou, Li-Xue Yin, Ming-Liang Zuo, Kui Kai Lau, Zhen Lei, Yingqing Feng, Bryan P Yan, Wen-Sheng Yue, Wen-Jun Zhang, Yuk-Ming Lau, Hin-Wai LUI, Koon-Ho Chan, Toi Meng Mok, Weng-Chio Tam, Kun-Chong Tam, Xiuhua Feng, Xiaofei Jiang, Guanming Tan, Mario Alberto Evora

“…The home-based AF screening system comprises (1) a handheld single-lead ECG recorder (Comfit Healthcare Devices, Hong Kong SAR, China) and (2) a patient-facing smartphone application specially designed for the study. …”
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Shifting shadows: Assessing the habitat and climate change response of binturong (Arctictis binturong) in the conservation landscape of the Asian continent by Imon Abedin, Tanoy Mukherjee, Ah Ran Kim, Hyun-Woo Kim, Soo Rin Lee, Shantanu Kundu

“…The binturong, Arctictis binturong is no exception, facing multiple threats such as habitat loss, hunting pressure, and illegal trade in South and Southeast Asia. …”
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The neutrophil–lymphocyte ratio as a risk factor for all-cause mortality among individuals with resolved HBV infection: evidence from the NHANES 1999–2018 by Chen Qiu, Chaojie Yu, Lanlan Yang, Siqi Liu, Qian Zhang, Shengnan Jia, Wenrui Wang, Zhenjing Jin, Dongdong Yu

“…Those with elevated NLR levels faced a substantially higher mortality risk compared to those with lower levels, as indicated by a Hazard Ratio (HR) of 1.84, with a 95% Confidence Interval (CI) of 1.17 to 2.89 (p < 0.05). …”
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Clinical validation of an artificial intelligence algorithm for classifying tuberculosis and pulmonary findings in chest radiographs by Thiago Fellipe Ortiz de Camargo, Thiago Fellipe Ortiz de Camargo, Guilherme Alberto Sousa Ribeiro, Guilherme Alberto Sousa Ribeiro, Maria Carolina Bueno da Silva, Luan Oliveira da Silva, Pedro Paulo Teixeira e Silva Torres, Denise do Socorro Rodrigues da Silva, Mayler Olombrada Nunes de Santos, William Salibe Filho, Marcela Emer Egypto Rosa, Magdala de Araujo Novaes, Thiago Augusto Massarutto, Osvaldo Landi Junior, Elaine Yanata, Marcio Rodrigues da Cunha Reis, Gilberto Szarf, Pedro Vieira Santana Netto, Joselisa Peres Queiroz de Paiva

“…However, physicians, not specialists, are often the first ones to read them, frequently facing challenges in accurate interpretation. Artificial Intelligence (AI) algorithms could be of great help, but using real-world data is crucial to ensure their effectiveness in diverse healthcare settings. …”
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Comparison of the adequacies of the OSCE and vOSCE to assess the competencies required under Brazilian medical curriculum guidelines: a multicenter study by Hervaldo Sampaio Carvalho, Maria do Carmo Barros Melo, Fabiana Maria Kakehasi, Priscila Menezes Ferri Liu, Fernanda Gontijo Minafra Silveira Santos, Ricardo Luiz de Melo Martins, Marilene Vale de Castro Monteiro, Marcelo Esteves Chaves Campos, Roberto Zonato Esteves, Matheus Belloni Torsani, Iolanda de Fátima Lopes Calvo Tiberio, Akihito Inca Atahualpa Urdiales, Andrea Mora De Marco Novellino, Rosiane Viana Zuza Diniz, Helena Ferreira Moura, Maria Alice de Vilhena Toledo, Célia Regina Machado Saldanha, Andrea Pedrosa Ribeiro Alves Oliveira, Patricia Zen Tempski, Itamar de Souza Santos, Milton de Arruda Martins

“…Conclusion The vOSCE can be employed to assess relevant competencies. However, it faces limitations regarding 8% (8/100) of the items, and some items (3%) cannot be assessed via either method. …”
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Ecological security driving mechanisms and optimization of zoning in Chinese urban agglomerations: A case study of the central plains urban agglomeration by Jinyuan Zhang, Xuning Qiao, Yongju Yang, Liang Liu, Yalong Li, Shengnan Zhao

“…The global ecological security framework is facing unprecedented challenges and transformations, with ecological security issues transcending national and regional boundaries and evolving into a global concern. …”
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Higher frequency of interstate over international transmission chains of SARS-CoV-2 virus at the Rio Grande do Sul - Brazil state borders by Filipe Zimmer Dezordi, José Valter Joaquim Silva Júnior, Terimar Facin Ruoso, Angela Giovana Batista, Pedro Mesquita Fonseca, Larissa Paim Bernardo, Richard Steiner Salvato, Tatiana Schäffer Gregianini, Thaísa Regina Rocha Lopes, Eduardo Furtado Flores, Rudi Weiblen, Patrícia Chaves Brites, Mônica de Medeiros Silva, João Batista Teixeira da Rocha, Gustavo de Lima Barbosa, Lais Ceschini Machado, Alexandre Freitas da Silva, Marcelo Henrique Santos Paiva, Matheus Filgueira Bezerra, Tulio de Lima Campos, Tiago Gräf, Daniel Angelo Sganzerla Graichen, Elgion Lucio da Silva Loreto, Gabriel da Luz Wallau

“…Brazil's COVID-19 response has faced challenges due to the continuous emergence of variants of concern (VOCs), emphasizing the need for ongoing genomic surveillance and retrospective analyses of past epidemic waves to reassess and fine tune containment protocols. …”
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Identification of standing dead trees in Robinia pseudoacacia plantations across China’s Loess Plateau using multiple deep learning models by Li Zhang, Xiaodong Gao, Shuyi Zhou, Zhibo Zhang, Tianjie Zhao, Yaohui Cai, Xining Zhao

“…As one of the most active tree-planting regions globally, the CLP primarily aims to achieve soil and water conservation despite facing challenges such as limited rainfall and frequent extreme drought events. …”
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Designing a Multimodal and Culturally Relevant Alzheimer Disease and Related Dementia Generative Artificial Intelligence Tool for Black American Informal Caregivers: Cognitive Walk... by Cristina Bosco, Ege Otenen, John Osorio Torres, Vivian Nguyen, Darshil Chheda, Xinran Peng, Nenette M Jessup, Anna K Himes, Bianca Cureton, Yvonne Lu, Carl V Hill, Hugh C Hendrie, Priscilla A Barnes, Patrick C Shih

“… BackgroundMany members of Black American communities, faced with the high prevalence of Alzheimer disease and related dementias (ADRD) within their demographic, find themselves taking on the role of informal caregivers. …”
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Improving Air Quality and Childhood Respiratory Health in Mongolia: The Impact of the Raw Coal Ban and COVID-19 Restrictions—An Interrupted Time-Series Analysis by Emma Dickinson-Craig, Terkhen Turbat, Karla Hemming, Francis D. Pope, Suzanne E. Bartington, Suvdaa Anjaa, Sumiya Davaa, Rosie Day, Damdindorj Boldbaatar, Chimedsuren Ochir, David Warburton, Graham Neil Thomas, Jargalsaikhan Badarch, Semira Manaseki-Holland

“…Outputs from Mongolia’s continuous air quality mitigation efforts provide useful insights for countries facing similar challenges.…”
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Observational cohort study of a group-based VR program to improve mental health and wellbeing in people with life-threatening illnesses by Hannes Kettner, Hannes Kettner, David R. Glowacki, David R. Glowacki, Justin Wall, Justin Wall, Justin Wall, Robin L. Carhart-Harris, Robin L. Carhart-Harris, Leor Roseman, Leor Roseman, Joseph L. Hardy, Joseph L. Hardy

“…Relatively few interventions are available to address the existential concerns of individuals facing LTI, while treatment of the underlying physical ailment typically remains the priority of the healthcare system. …”
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Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives by Dagmawi Woldesenbet, Yalewayker Tegegne, Abdulhakim Mussema, Elias Tamene, Kemal Mohamed, Wagaw Abebe, Melese Mekuria, Kasahun Bogale, Habtamu Geremew, Mufta Muzemil Shifa, Mulugeta Aemero Tegegne

“…BackgroundEthiopia has faced a significant burden of malaria, enduring endemic transmission in various regions. …”
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Vulnerability, Resilience and Adaptation of Lagos Coastal Communities to Flooding by Prince Emeka Ndimele, Akinloye Emmanuel Ojewole, Gabriel Olarinde Mekuleyi, Lateef Akorede Badmos, Christopher Monday Agosu, Emmanuel Sunday Olatunbosun, Oluseyi Olaide Lawal, Jamiu Adebayo Shittu, Olufemi Olabode Joseph, Kehinde Moyosola Ositimehin, Felix Chinsom Ndimele, Catherine Oluwalopeye Ojewole, Iman Olawunmi Abdulganiy, Odunayo Temitope Ayodele

“…The state also ranked 30th among 136 port cities in terms of population exposure to flooding under a past climate scenario (2005) and 15th under a future climate scenario (2070s). The state faces significant environmental strains as a result of its geo-economic status. …”
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Validation of heavy metals in geothermal to support water management practices and mitigation strategies by G.M. Idroes, D.P. Rezeki, K. Khairi, K. Khairan, R. Idroes, E. Suhartono, R. Prasetio, S.A. Rahman, S. Suhendrayatna

“…This confirmed that the identified concentrations of metals were reliable and could serve to evaluate the possible health risks faced by residents and users of the water source.FINDINGS: The analysis revealed that copper, chromium, zinc, and iron concentrations were within the permissible limits for safe drinking water as established by national and international health guidelines. …”
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