Influence of Full-Life Cycle Wheel Profile on the Contact Performance of Wheel and Standard Fixed Frog in Heavy Haul Railway by He Ma, Jinming Zhang, Jun Zhang, Tao Tao Jin, Chun Yu Song

“…The coupling dynamic models of the vehicle-fixed frog system are established to calculate the change regulation of displacement, contact force, and acceleration when a vehicle passes through the standard fixed frog at a speed of 50 km/h in the facing move in the diverging line. Besides, the finite element models of wheel and standard fixed frog at key positions are developed to simulate the contact patch and distribution of von Mises stress in the regions of the wheel-fixed frog. …”
Get full text

The interactive use of augmented reality for educating the elderly on common age-related eye disease by Yuet Yi Hung, Wang Yee Chu, Juming Jiang, Wing Yiu Yeung, Wing Huen Yan, Tai On Kwok, Yau Kei Chan

“…Methods An AR-based education workshop was designed for the elderly to understand the major visual symptoms of several eye diseases and experience the challenges faced by visually impaired people. The effectiveness of the workshop was assessed by conducting pre- and post-activity surveys to measure the knowledge acquisition of the participants from this workshop. …”
Get full text

Looking outside the box with a pathology aware AI approach for analyzing OCT retinal images in Stargardt disease by Parisa Khateri, Tiana Koottungal, Damon Wong, Rupert W. Strauss, Lucas Janeschitz-Kriegl, Maximilian Pfau, Leopold Schmetterer, Hendrik P. N. Scholl

“…The development of effective therapies faces the challenge of identifying appropriate outcome measures that accurately reflect treatment benefits. …”
Get full text

Enhancing Biomedical Research Through Strategic Funding: A Comprehensive Review by Raju Vaishya, Abhishek Vaish, Marius M. Scarlat

“…Tackling the identified challenges is crucial to strengthen biomedical research efforts and ensure a variety of perspectives in addressing the urgent health issues facing society. Improved funding strategies can lead to better research outcomes and advancements in public health.…”
Get full text

Eukaryotic plankton community and assembly processes in a large-scale water diversion project in China by Liming Zhu, Lihui Feng, Daoxi Zhang, Fang Shi, Xi Zou, Qing Yang, Shan He, Wen Zhu

“…Abstract The Middle Route of the South to North Water Diversion Project (MRP) and its water source, the Danjiangkou Reservoir (DJK), play a pivotal role in mitigating the chronic water scarcity challenges faced by northern China. Eukaryotic plankton are widespread in aquatic ecosystems, which are crucial for the water quality stability of DJK and MRP, yet comparative studies on their contemporaneous dynamics and assembly processes are scarce. …”
Get full text

An MLLM-Assisted Web Crawler Approach for Web Application Fuzzing by Wantong Yang, Enze Wang, Zhiwen Gui, Yuan Zhou, Baosheng Wang, Wei Xie

“…Web application fuzzing faces significant challenges in achieving comprehensive test interface (attack surface) coverage, primarily due to the complexity of user interactions and dynamic website architectures. …”
Get full text

Signal Game Analysis on the Effectiveness of Coal Mine Safety Supervision Based on the Affective Events Theory by Xue Yang, Yang Tian, Kai Feng, Juan Yang, Shu-hui Zhang, Shengnan Wang

“…Under the separating equilibrium state, the emotional supervision system faces “the paradox of almost totally safe systems” and will be broken; the emotion-driven miners disguising any negative emotions will be permitted to work in the coal mine, creating a safety risk. …”
Get full text

Post-apartheid complexities of Xitsonga and mathematics teaching in rural foundation phase classrooms: A case of number patterns by Hlamulo Wiseman Mbhiza, Ayanda Zondo, Sibongile Mlangeni, Vuyelwa Brenda Mpitso

“…The findings reveal the complexities involved in using Xitsonga to teach mathematical concepts. Teachers faced challenges related to language proficiency, pedagogical strategies, and the integration of local cultural contexts into their teaching practices.…”
Get full text

Exploring the potentialities and challenges of deep learning for simulation and prediction of urban sprawl features by Ange Gabriel Belinga, Stéphane Cedric Tékouabou Koumetio, Mohamed El Haziti

“…Rapid urbanization poses several challenges, especially when faced with an uncontrolled urban development plan. …”
Get full text

Advancing risk assessment in renewable power plant construction: an integrated DEA-SVM approach by Reza Rasinojehdehi, Seyyed Najafi

“…Despite its high potential for constructing solar power plants, Iran faces limitations that require careful consideration. …”
Get full text

Structure and function of a β-1,2-galactosidase from Bacteroides xylanisolvens, an intestinal bacterium by Yutaka Nakazawa, Masumi Kageyama, Tomohiko Matsuzawa, Ziqin Liang, Kaito Kobayashi, Hisaka Shimizu, Kazuki Maeda, Miho Masuhiro, Sei Motouchi, Saika Kumano, Nobukiyo Tanaka, Kouji Kuramochi, Hiroyuki Nakai, Hayao Taguchi, Masahiro Nakajima

“…The 2-hydroxy group and the anomeric methyl group of methyl β-galactopyranose faces in the direction of subsite −1 and the solvent, respectively. …”
Get full text

Emerging trends in cervical cancer incidence among younger Taiwanese generations: an urban–rural comparison by Ya-Xuan Wu, Yi-Chu Chen, Jing-Rong Jhuang, Chun-Ju Chiang, Wen-Chung Lee

“…The 1990-born urban cohort faced a risk 1.9 times higher than their 1975-born counterparts, while the risk for the 1990-born rural cohort was 1.4 times greater than those born in 1980. …”
Get full text

Changes and their effects on working and daily life time use allocation between work-from-home and office work days during the telework period: insights from the survey in Japan by Eri Aoki, Eri Aoki, Ai Hiramatsu, Keisuke Hanaki

“…In contrast, the “Unsuitable for WFH” group faced increased office-day workloads and reduced WFH productivity, indicating that telework’s effectiveness depends on job and individual characteristics.ConclusionThe findings highlight telework’s potential to enhance wellbeing and sustainability but also underscore the need for tailored policies that address diverse job requirements and personal characteristics. …”
Get full text

Determination of Carbon Footprint for Local Administrations: A Case Study for Ümraniye Municipality by Betül Hande GÜRSOY HAKSEVENLER, G. Nur Çelik Onat, Begüm Akpinar, Tuğba Bedel

“…Since the World is facing with detrimental effects of the global warming, some precautions are needed to be taken at international, national, regional and local levels. …”
Get full text

COVID-19 Mortality in a Pediatric Patient with Hemoglobin SC Disease and Alpha-Thalassemia Trait by Joshua E. Motelow, Stacie Kahn, Patrick T. Wilson

“…We outline clearly the course of illness and treatments trialed, which can prove beneficial to providers facing similar challenges as this virus continues to strike areas around the world. …”
Get full text

Association between Pan‐Immune Inflammation Value and Sarcopenia in Hypertensive Patients, NHANES 1999–2018 by Lu Long, Bingquan Xiong, Zhidan Luo, Haiyan Yang, Qiang She

“…After controlling for confounding factors, our study found that those in the highest PIV quartile faced a 36% greater risk of developing sarcopenia compared to those in the lowest quartile (OR = 1.36, 95% confidence interval [CI]: 1.04–1.77). …”
Get full text

The Science of Disaster Medicine: From Response to Risk Reduction by Hüseyin Koçak, Kerem Kınık, Cüneyt Çalışkan, Kurtuluş Açıksarı

“…Disaster medicine aimed to ensure that health services and facilities are operational both in the pre- and post-disaster periods to prevent and reduce the negative health circumstances of the society facing disaster risks. It is a discipline with slow scientific progress due to unclearly systematized multidisciplinary structure and sub-study areas. …”
Get full text

Spatiotemporal evolution of multiple time scale precipitation in Yellow River Basin based on Köppen-Geiger Trend Indicator System by Hao Ke, Wenzhuo Wang, Zengchuan Dong, Xinhua Zhu, Zhuozheng Li, Chao Lü, Dawei Jin, Weilin Liu

“…Climate zones with decreasing annual precipitation also show greater variability in monthly precipitation, facing the dual challenges of decreasing water resources and extreme precipitation events.…”
Get full text

The influence of Hermetia illucens L. frass on the health, stress, and development of barley by Monika Grzanka, Łukasz Sobiech, Dominika Radzikowska-Kujawska, Zuzanna Sawinska, Przemysław Łukasz Kowalczewski, Stanisław Świtek, Grzegorz Skrzypczak, Przemysław Kardasz

“…Barley cultivation faces challenges from changing climate conditions, including the increasing threat of drought. …”
Get full text

Implementation of the Standard Inpatient Class Policy at RSUP Dr. Tadjuddin Makassar by Muhammad Alwy Arifin, Andi Luthfiyyah Anna, Dian Saputra Marzuki, Sukri Palutturi, Ryryn Suryaman Prana Putra

“…Result: The "Man" input is adequate but faces obstacles. There is no specific budget allocation ("Money") and no difference in financial management before and after policy implementation. …”
Get full text