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Evolution of the umbilical cord blood proteome across gestational development
Published 2025-01-01Get full text
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Evolution of sub-ice-shelf channels reveals changes in ocean-driven melt in West Antarctica
Published 2024-01-01Get full text
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Three-dimensional photoluminescence imaging of threading dislocations in GaN by sub-band optical excitation
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Rift propagation signals the last act of the Thwaites Eastern Ice Shelf despite low basal melt rates
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Endoplasmic reticulum protein TXNDC5 modulates thyroid eye disease TGF-β1-induced myofibroblast transdifferentiation
Published 2024-12-01“…Aim There remain limited therapies to treat thyroid eye disease (TED) orbital fibrosis, highlighting the urgency to develop novel targets. …”
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Single-cell transcriptomics in thyroid eye disease
Published 2024-12-01“…Thyroid eye disease (TED) is a poorly understood autoimmune condition affecting the retroorbital tissue. …”
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Evaluation of Minds in Motion, a fitness program for people living with dementia and their caregivers
Published 2025-03-01Get full text
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The relationship between cholesterol levels and thyroid eye disease
Published 2025-02-01“…Background: Thyroid eye disease (TED) is the most prevalent extrathyroidal manifestation of Graves’ disease (GD). …”
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Nonsurgical management of upper eyelid retraction in thyroid eye disease
Published 2024-12-01“…Upper eyelid retraction (UER) is the most common sign of thyroid eye disease (TED) and may result in lagophthalmos and exposure keratopathy. …”
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Incidence of the postpartum diagnosis of thyroid eye disease in relation to thyroid function in Graves’ disease
Published 2025-01-01“…The active phase TED was observed in 8 of the 72 patients. Of the 72 patients newly diagnosed with TED in postpartum, two-thirds were accompanied by thyroid dysfunction and 8 of them were in active phase.…”
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A curative effect evaluation of intensity-modulated radiation therapy combined with periorbital triamcinolone acetonide injection in treating thyroid eye disease patients with acti...
Published 2025-01-01“…A total of 156 eligible patients were selected from the TED patient database of the Ophthalmology Department of West China Hospital of Sichuan University. …”
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A randomised, double-masked, placebo-controlled trial evaluating the efficacy and safety of teprotumumab for active thyroid eye disease in Japanese patientsResearch in context
Published 2025-02-01“…Main inclusion criteria were as follows: age 20–80 years; Graves’ disease, in a euthyroid or mild hypo/hyperthyroid state; clinical activity score (CAS) ≥3; moderate-to-severe TED; ≥3-mm increase in proptosis before TED onset and/or proptosis ≥18 mm at baseline; and TED duration ≤9 months. …”
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Transition from hypothyroidism to Graves’ disease, development of thyroid eye disease, progression to optic neuropathy after inpatient pulse therapy, and long-term administration o...
Published 2025-01-01“…A 55-year-old woman transitioned from hypothyroidism to Graves’ disease (GD) and then developed thyroid eye disease (TED) with proptosis and diplopia. After three cycles of daily methylprednisolone pulse therapy, her condition progressed to dysthyroid optic neuropathy with decreased visual acuity in both eyes. …”
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Investigating factors influencing quality of life in thyroid eye disease: insight from machine learning approaches
Published 2025-01-01“…Aims: Thyroid eye disease (TED) is an autoimmune orbital disorder that diminishes the quality of life (QOL) in affected individuals. …”
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Longitudinal association of thyroid-stimulating immunoglobulin levels with clinical characteristics in thyroid eye disease
Published 2022-06-01“…Objectives The clinical course of thyroid eye disease (TED) is heterogeneous and predicting patients who may develop the severe sequelae of the disease is difficult. …”
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