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41
Antigen Presentation in the Gut
Published 1990-01-01“…Suppressor T cells and unresponsive T helper cells in the mucosa appear to mediate systemic T cell tolerance of dietary antigens. …”
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42
Long-Term GAD-alum Treatment Effect on Different T-Cell Subpopulations in Healthy Children Positive for Multiple Beta Cell Autoantibodies
Published 2022-01-01“…This difference remained 24 months after the first treatment for lymphocytes (p=0.027), T-cells (p=0.022), T-helper cells (p=0.048), and cytotoxic T-cells (p=0.018). …”
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43
Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma
Published 2012-01-01“…T helper 17 () is a novel subset of T helper cells that has recently been identified in the hepatocellular carcinoma (HCC) tumor environment. …”
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44
Loss and Dysregulation of Th17 Cells during HIV Infection
Published 2013-01-01“…T helper 17 (Th17) cells are a unique lineage of T helper cells that are enriched in mucosal tissues and are thought to play a central role in protecting the integrity of the mucosal barrier and maintaining immune homeostasis at mucosal sites. …”
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45
Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse
Published 2015-01-01“…However, only oil-induced BALB/c showed increased levels of natural helper cells (NHC) which could be important in the myeloma induction.…”
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46
Immunoregulation of NKT Cells in Systemic Lupus Erythematosus
Published 2015-01-01“…In this review, we mainly summarized the most recent findings about the behavior of NKT cells in SLE patients and mouse models, as well as how NKT cells affect the proportion of T helper cells and the production of autoreactive antibodies in the progress of SLE. …”
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47
The Effects of TLR Activation on T-Cell Development and Differentiation
Published 2012-01-01“…TLRs are also involved in T-cell development and can reprogram Treg cells to become helper cells. T cells consist of various subsets, that is, Th1, Th2, Th17, T follicular helper (Tfh), cytotoxic T lymphocytes (CTLs), regulatory T cells (Treg) and these originate from thymic progenitor thymocytes. …”
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48
Pas de Deux: Active Ulcerative Colitis in an HIV-Positive Patient
Published 1996-01-01“…This case raises questions about immune regulation in ulcerative colitis because the patient has active disease in addition to a reduced number of T helper cells. It also presents a difficult management problem because the patient has a limited life expectancy and is reluctant to accept colectomy, and further immunosuppressive therapy may be dangerous.…”
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49
Tracheal tuft cells release ATP and link innate to adaptive immunity in pneumonia
Published 2025-01-01“…Tuft cell stimulation also involves an adaptive immune response through recruitment of IL-17A secreting T helper cells. Collectively, the results provide a molecular framework defining tuft cell dependent regulation of both innate and adaptive immune responses in the airways to combat bacterial infection.…”
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50
12/15-Lipoxygenase Is an Interleukin-13 and Interferon-γ Counterregulated-Mediator of Allergic Airway Inflammation
Published 2010-01-01“…Interleukin-13 and interferon-γ are important effectors of T-helper cells. Interleukin-13 increases expression of the arachidonic acid-metabolizing enzyme, 15-lipoxygenase-1, in a variety of cell types. 15-lipoxygenase-1 is dramatically elevated in the airways of subjects with asthma. …”
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51
The Role of Th17 Cells and IL-17 in Th2 Immune Responses of Allergic Conjunctivitis
Published 2020-01-01“…It has been found that new subpopulations of T-helper cells, Th17 cells that produce interleukin-17 (IL-17), play an important role in the Th2-mediated pathogenesis of conjunctivitis. …”
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52
Colitis in spondyloarthritis
Published 2020-01-01“…Mucosal inflammation leads to disruption of the epithelial barrier and activation of antigen-presenting cells and T-helper cells, which then home to synovium to cause inflammation maintaining the gut synovial axis. …”
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53
The Role of the IL-12 Cytokine Family in Directing T-Cell Responses in Oral Candidosis
Published 2011-01-01“…In this regard, the role of Th1/2, helper cells, together with the recently identified Th17 and Treg cells in candidosis will be discussed. …”
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54
Role of T-Cell Polarization and Inflammation and Their Modulation by n-3 Fatty Acids in Gestational Diabetes and Macrosomia
Published 2016-01-01“…Th (T helper) cells are differentiated into either Th1 or Th2 phenotype. …”
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55
Pneumocystis carinii: A Review of an Important Opportunistic Pathogen in AIDS
Published 1991-01-01“…Individuals with damaged T helper cells secondary to malignancies (eg, Hodgkin’s lymphoma), drugs (eg, cyclosporine, steroids), or certain infections (eg, human immunodeficiency virus) are at particular risk. …”
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56
In silico data mining of large-scale databases for the virtual screening of human interleukin-2 inhibitors
Published 2021-03-01“…Interleukin-2 (IL-2) is involved in the activation and differentiation of T-helper cells. Uncontrolled activated T cells play a key role in the pathophysiology by stimulating inflammation and autoimmune diseases like arthritis, psoriasis and Crohn’s disease. …”
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57
The Immunogenicity of HLA Class II Mismatches: The Predicted Presentation of Nonself Allo-HLA-Derived Peptide by the HLA-DR Phenotype of the Recipient Is Associated with the Format...
Published 2017-01-01“…The HLA-DR phenotype of recipients contributes to DSA formation by presenting allo-HLA-derived peptides to T-helper cells, which induces the differentiation of B cells into plasma cells. …”
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58
Decreased Regulatory T Cells in Vulnerable Atherosclerotic Lesions: Imbalance between Pro- and Anti-Inflammatory Cells in Atherosclerosis
Published 2015-01-01“…The following results were observed: in unstable lesions, significantly higher numbers of proinflammatory cells like DCs, T helper cells, cytotoxic T cells, and natural killer cells were detected compared to stable plaques. …”
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59
Increased Peripheral Proinflammatory T Helper Subsets Contribute to Cardiovascular Complications in Diabetic Patients
Published 2014-01-01“…The frequencies of peripheral total CD4+ T helper cells, proinflammatory Th1, Th17, and Th22 subsets were determined by flow cytometry in diabetic patients with or without CHD (n=42 and 67, resp.). …”
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60
Deep immunophenotypic dissection and clinical impact of T cells in the follicular lymphoma microenvironment
Published 2025-02-01“…FL-UT cases with either increased T-reg TC or increased T follicular helper cells (TFH) showed reduced time to first treatment (…”
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