Virological Aspects of COVID-19 in Patients with Hematological Malignancies: Duration of Viral Shedding and Genetic Analysis by Asma Themlaoui, Massimo Ancora, Kais Ghedira, Yosra Mhalla, Manel Hamdoun, Maroua Bahri, Lamia Aissaoui, Raihane Ben Lakhal, Adriano Di Pasquale, Cesare Camma, Olfa Bahri

“…Additional studies based on cell culture analysis are needed to confirm these findings.…”
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PreS1 deletions in genotype C HBV leads to severe hepatic inflammation and hepatocarcinogenesis via the IRE1-JNK axis by Yu-Min Choi, Junghwa Jang, Dong Hyun Kim, Ziyun Kim, Eunseo Kim, Won Hyeok Choe, Bum-Joon Kim

“…Methods: The effects of HBV replicative capacity, ER stress signaling, inflammation, cell death, and tumorigenesis resulting from PreS1 deletions were investigated through in vitro and in vivo experiments. …”
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Longitudinal association between DNA methylation and type 2 diabetes: findings from the KORA F4/FF4 study by Liye Lai, Dave Laurence Juntilla, Monica Del, Monica Del C Gomez-Alonso, Harald Grallert, Barbara Thorand, Aiman Farzeen, Wolfgang Rathmann, Juliane Winkelmann, Holger Prokisch, Christian Gieger, Christian Herder, Annette Peters, Melanie Waldenberger

“…Linear mixed-effects models were employed to identify significant associations between methylation sites and diabetes status, as well as with fasting plasma glucose (FPG), hemoglobin A1c (HbA1c), homoeostasis model assessment of beta cell function (HOMA-B), and homoeostasis model assessment of insulin resistance (HOMA-IR). …”
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Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections by Emily Lydon, Christina M. Osborne, Brandie D. Wagner, Lilliam Ambroggio, J. Kirk Harris, Ron Reeder, Todd C. Carpenter, Aline B. Maddux, Matthew K. Leroue, Nadir Yehya, Joseph L. DeRisi, Mark W. Hall, Athena F. Zuppa, Joseph Carcillo, Kathleen Meert, Anil Sapru, Murray M. Pollack, Patrick McQuillen, Daniel A. Notterman, Charles R. Langelier, Peter M. Mourani

“…The TA signature of vLRTI was characterized by 200 DE proteins (Padj <0.05) with upregulation of interferons and T cell responses and downregulation of inflammation-modulating proteins including FABP and MIP-5. …”
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Association of blood inflammatory phenotypes and asthma burden in children with moderate-to-severe asthma by Amir Hossein Alizadeh Bahmani, Susanne J.H. Vijverberg, Simone Hashimoto, Christine Wolff, Catarina Almqvist, Lizan D. Bloemsma, Susanne Brandstetter, Paula Corcuera-Elosegui, Mario Gorenjak, Susanne Harner, Anna M. Hedman, Michael Kabesch, Leyre López-Fernández, Aletta D. Kraneveld, Anne H. Neerincx, Maria Pino-Yanes, Uroš Potočnik, Olaia Sardón-Prado, Barbara S. Dierdorp, Tamara Dekker, Nariman K.A. Metwally, Jan Willem Duitman, René Lutter, Paul Brinkman, Mahmoud I. Abdel-Aziz, Anke H. Maitland-van der Zee

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Application of lacrimal gland ultrasonography in the evaluation of chronic ocular graft-versus-host-disease by Mingxia Zhong, Siyuan Liu, Jinghan Luo, Qin Zhang, Zhou Yang, Shanshan Zhang

“…ObjectiveTo investigate the effectiveness of lacrimal gland ultrasonography in the assessment of chronic ocular graft-versus-host-disease (oGVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and to establish the correlation between the ocular surface and ultrasonographic results.MethodThe cross-sectional study included 57 participants aged 18 and older, who were at least 100 days after allo-HSCT. …”
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Influencing factors of IgA nephropathy combined with hyperuricemia and a nomogram to predict the risk of hyperuricemia in IgA nephropathy patients by Zhou Jie, Xian Wei-ying, Li Ji-tian, Zeng Jin-cheng

“…There were significant differences in the male proportion （65.82% vs 47.40%）， body mass index ［BMI， （24.67 ± 4.52）kg/m2 vs （22.28 ± 3.17）kg/m2］， hypertension （43.04% vs 23.38%）， triglyceride ［TG， （2.16 ± 0.61）mmol/L vs （1.72 ± 0.30）mmol/L］， white blood cell count ［WBC， （7.28 ± 2.06）×109L vs （5.75 ± 1.52）×109L］， estimated glomerular filtration rate ［eGFR，（66.93 ± 19.85）mL·min-1·（1.73 m2）-1 vs （86.42 ± 22.37）mL·min-1·（1.73 m2）-1］ and IgA/C3 ［（3.07 ± 0.96） vs （2.35 ± 0.62）］ between HUA group and non-HUA group （P<0.05）. …”
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The effectiveness of convalescent plasma administered on the first day of admission for COVID-19 patients: an open-label randomized controlled trial by Saeed Mohammadi, Mandana Pouladzadeh, Hamidreza Kouhpayeh, Shamsi Okati, Mehdi Safdarian, Peyman Eshghi, Parastoo Moradi Choghakabodi, Shahabeddin Mashaei, Sharareh Sanei Sistani, Yalda Khani, Soheila Nasizadeh, Ahmad Reza Shamshiri, Amir Teimourpour, Haijuan Wang

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Global research trends in Chinese medicine for the treatment of non-alcoholic fatty liver disease (NAFLD): A bibliometric study by Kangjie li, Jie Wang, Ming Dang, Runxin Ren, Maomao Fu, Jing Wang, Qiao Zhang, Chongbo Zhao

“…Recent outbreak word analysis highlights 'cell' and 'steatohepatitis' as current hotspots, with 'NASH' anticipated to be a focal point in 2024. …”
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Preventing Severe COVID-19 with Tixagevimab-Cilgavimab in Hematological Patients Treated with Anti-CD20 Monoclonal Antibodies: An International Multicenter Study by Hovav Azuly, Tali Shafat, Daniel Grupel, Tzvika Porges, Ran Abuhasira, Ana Belkin, Ofir Deri, Yonatan Oster, Shadi Zahran, Ehud Horwitz, Netanel A. Horowitz, Hazim Khatib, Marjorie Vieira Batista, Anita Cassoli Cortez, Tal Brosh-Nissimov, Yafit Segman, Linor Ishay, Regev Cohen, Alaa Atamna, Amy Spallone, Roy F. Chemaly, Juan Carlos Ramos, Michal Chowers, Evgeny Rogozin, Noga Carmi Oren, Şiran Keske, Orit Wolfovitz Barchad, Lior Nesher, on behalf of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Respiratory Viruses (ESGREV)

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Cancer care in German centers of excellence during the first 2 years of the COVID-19 pandemic by Volker Arndt, Daniela Doege, Stefan Fröhling, Peter Albers, Hana Algül, Ralf Bargou, Carsten Bokemeyer, Martin Bornhäuser, Christian H. Brandts, Peter Brossart, Sara Yvonne Brucker, Tim H. Brümmendorf, Hartmut Döhner, Norbert Gattermann, Michael Hallek, Volker Heinemann, Ulrich Keilholz, Thomas Kindler, Cornelia von Levetzow, Florian Lordick, Ulf Peter Neumann, Christoph Peters, Dirk Schadendorf, Stephan Stilgenbauer, Thomas Zander, Daniel Zips, Delia Braun, Thomas Seufferlein, Gerd Nettekoven, Michael Baumann

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Diagnostic markers of severe diabetic macular edema in patients with type 2 diabetes by S.A. Suk, S.Yu. Mogilevskyy

“…According to OCT, area thickness was 355.68 ± 1.80 μm, min in fovea — 358.54 ± 2.40 μm, central sector — 401.06 ± 2.09 μm, volume — 10.42 ± 0.10 mm3, nerve fiber layer (NFL) + ganglion cell layer (GCL) + inner plexiform layer (IPL) average — 138.3 ± 0.7 μm, NFL + GCL + IPL min — 122.78 ± 0.60 μm, GCL — 97.2 ± 1.0 μm, NFL — 42.12 ± 0.20 μm. …”
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Genetic testing of ocular manifestations of proliferative syndrome to provide pathophysiology-oriented treatment by M.E. Weener, N.A. Bakunina, J.M. Salmasi, G.V. Poryadin, D. Barh, Yu.D. Kuznetsova, L.M. Balashova

“…Pirogov City Clinical Hospital No. 1, Moscow, Russian Federation</b> </p> <p> <b>⁴Pirogov Russian National Research Medical University, Moscow, Russian Federation</b> </p> <p> <i><b>Background</b>: uncontrolled cell proliferation of the ocular blood network is one of the leading causes of blindness and low vision worldwide. …”
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Investigating the Effect of Solanum lycopersicum L. (Tomato) Pomace on Growth Performance and some Blood Indices of Broiler Chickens by Meta-Analysis Method by Zahra Sahragard, seyyed javad Hosseini-vashan, Hossein Naeemipour Younesi, Seyyed Homayon Farhangfar

“…The antioxidant capacity of tomato pomace is related to the substances in it, especially lycopene, which reduces the effect of reactive oxygen species and the destructive effects of these compounds on the cell membrane and mitochondrial structure. Tomato pomace has a high fiber content, which may have undesirable effects on broiler performance. …”
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Short- and long-term effects of transcutaneous spinal cord stimulation on autonomic cardiovascular control and arm-crank exercise capacity in individuals with a spinal cord injury... by Samuel J E Lucas, Tom E Nightingale, Jet J C S Veldhuijzen van Zanten, Shin-Yi Chiou, Alex J Wadley, Rebekah A I Lucas, Daniel D Hodgkiss, Shane J T Balthazaar, Joseph F Welch, Phoebe A Cox

“…Secondary outcomes for AIM 1 include arterial blood pressure, respiratory function, cerebral blood velocity, skeletal muscle tissue oxygenation, along with concentrations of catecholamines, brain-derived neurotrophic factor and immune cell dynamics via venous blood sampling pre, post and 90 min post-exercise. …”
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An integrative analysis reveals cancer risk associated with artificial sweeteners by Jumin Xie, Ying Zhu, Zixuan Yang, Zhang Yu, Mingzhi Yang, Qingzhi Wang

“…GO biological process analysis indicated that these targets are involved in the regulation of apoptosis, gene expression, and cell proliferation. Thirty-five core targets were identified from the intersection of the 48 significant AS-cancer targets and genes in the 'Pathways in cancer' (map05200). …”
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Inflamed immune phenotype predicts favorable clinical outcomes of immune checkpoint inhibitor therapy across multiple cancer types by Jeanne Shen, Sergio Pereira, Chan-Young Ock, Yung-Jue Bang, Seulki Kim, Sehhoon Park, Se-Hoon Lee, George A Fisher, Young Kwang Chae, Yoon-La Choi, Jin-Haeng Chung, Tony S K Mok, Leeseul Kim, Jun-Eul Hwang, Gahee Park, Sanghoon Song, Seunghwan Shin, Yoojoo Lim, Wonkyung Jung, Heon Song, Hyojin Kim, Taebum Lee, Sukjun Kim, Chang Ho Ahn, Seokhwi Kim, Ben W Dulken, Stephanie Bogdan, Maggie Huang, Chiyoon Oum, Siraj M. Ali

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Recurrent adenoid cystic carcinoma of the left upper palate accompanied by massive maxillary hemorrhage: a case report and literature review by ZHANG Wangru, CHEN Yuanyuan, LI Zhiping, MENG Jian

“…An emergency tracheotomy was performed to relieve the obstruction of the patient’s respiratory tract, and a red blood cell suspension was transfused to address the hemorrhagic shock. …”
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Effectiveness of hCMV, mEF1a and mAct promoters on driving of foreign gene expression in transgenic zebrafish by . Alimuddin, G. Yoshizaki, O. Carman, T. Takeuchi

“…Each of the constructs in circular DNA form was microinjected into 1-cell stage embryos at a concentration of 30mg/ml. …”
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Association of Corticosteroid Inhaler Type with Saliva Microbiome in Moderate-to-Severe Pediatric Asthma by Amir Hossein Alizadeh Bahmani, Mahmoud I. Abdel-Aziz, Simone Hashimoto, Corinna Bang, Susanne Brandstetter, Paula Corcuera-Elosegui, Andre Franke, Mario Gorenjak, Susanne Harner, Parastoo Kheiroddin, Leyre López-Fernández, Anne H. Neerincx, Maria Pino-Yanes, Uroš Potočnik, Olaia Sardón-Prado, Antoaneta A. Toncheva, Christine Wolff, Michael Kabesch, Aletta D. Kraneveld, Susanne J. H. Vijverberg, Anke H. Maitland-van der Zee, on behalf of the SysPharmPediA consortium

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