lncRNA-SNHG14 Plays a Role in Acute Lung Injury Induced by Lipopolysaccharide through Regulating Autophagy via miR-223-3p/Foxo3a by Jun Hong, Shijing Mo, Fangxiao Gong, Zongbin Lin, Hanhui Cai, Ziqiang Shao, Xianghong Yang, Renhua Sun, Qiangnu Zhang, Jingquan Liu

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Characterization and dosimetric predictors for absolute lymphocyte count changes during neoadjuvant chemoradiotherapy with or without pembrolizumab for esophageal squamous cell car... by Wei-Xiang Qi, Shuyan Li, Shujun Zhang, Chao Li, Huan Li, Xiaomei Li, Chaofen Zhao, Gang Cai, Cheng Xu, Xuan Han, Yibin Zhang, Jiayi Chen, Shengguang Zhao

“…A total of 198 patients finally received surgery. Of them, 98 patients archived pCR (49.5%), with 50.4% (68/135 patients) in nCRT with pembrolizumab and 47.6% (30/63) in nCRT alone(p = 0.94), respectively. …”
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Combining single-cell analysis and molecular docking techniques to construct a prognostic model for colon adenocarcinoma and uncovering inhibin subunit βb as a novel therapeutic ta... by Qinqing Wu, Qinqing Wu, Lu Ye, Yuwei Wu, Mengyu Zhao, Mengyu Zhao, Jiaxin Lu, Yanping Yu, Yanping Yu, Yixiao Niu, Yixiao Niu, Luxiao Zhang, Peijun Zuo, Peijun Zuo

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Cardiac repair using regenerating neonatal heart tissue-derived extracellular vesicles by Hanjing Li, Yining Liu, Yuqing Lin, Sijia Li, Chenlu Liu, Ao Cai, Wei Li, Wanyu Zhang, Xinlu Gao, Zhongyu Ren, Haoyu Ji, Yang Yu, Xiuxiu Wang, Wenya Ma, Ning Wang, Dan Zhao, Tianlong Li, Yu Liu, Benzhi Cai

“…Here, we report that EVs from regenerating neonatal heart tissues, after apical resection surgery (AR-Neo-EVs), exhibit stronger pro-proliferative, anti-apoptotic, and pro-angiogenesis activities than EVs from neonatal mouse cardiac tissues (Neo-EVs), effects which are absent in adult mouse heart-derived EVs (Adu-EVs). …”
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Sedentary Behavior and Its Association With Psychological Well-Being and Sleep Quality in Adolescents: Evidence from a Propensity Score Analysis by Zhang L, Zhao S, Zhao S, Zheng H, Ke Y, Yang W, Lei M

“…Lirong Zhang,1 Shaocong Zhao,1 Shuangyin Zhao,1 Hua Zheng,2 Yizhen Ke,1 Weichen Yang,1 Mingxing Lei3,4 1Department of Physical Education, Xiamen University of Technology, Xiamen, Fujian, 361024, People’s Republic of China; 2College of Physical Education and Health Science, Chongqing Normal University, Chongqing, 401331, People’s Republic of China; 3Department of Orthopaedics, Hainan Hospital of Chinese PLA General Hospital, Sanya, 572013, People’s Republic of China; 4Nursing Department, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, People’s Republic of ChinaCorrespondence: Lirong Zhang, Department of Physical Education, Xiamen University of Technology, No. 600, Ligong Road, Jimei District, Xiamen, 361024, Fujian, People’s Republic of China, Tel +86 13806063882, Email 22674481@qq.com Mingxing Lei, Department of Orthopedic Surgery, Chinese PLA General Hospital, Beijing, 100039, People’s Republic of China, Tel +86 18811772189, Email leimingxing2@sina.comBackground: Sedentary lifestyles among adolescents have been associated with various health concerns, particularly regarding psychological well-being and sleep quality. …”
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Breast cancers with neuroendocrine differentiation: Retrospective case studies series from a single institution based on the 2019 WHO classification by Youngkyung Jeon, Ji-Yeon Kim, Jin Seok Ahn, Young-Hyuck Im, Kyuehee Choi, Sun Young Jeong, Yeji Jung, Jaeyeon Jang, Dae-Ho Choi, Joohyun Hong, Hyo Jung Kim, Soo Youn Cho, Yeon Hee Park

“…All patients were treated with curative intent surgery; five patients received neoadjuvant chemotherapy, twelve patients received radiotherapy, six patients received adjuvant chemotherapy, and eight patients received hormone therapy. …”
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Phenotypic Presentation of Children with Joint Hypermobility: Preclinical Signs by Mateus Marino Lamari, Neuseli Marino Lamari, Michael Peres de Medeiros, Gerardo Maria de Araújo Filho, Adriana Barbosa Santos, Matheus Gomes Giacomini, Vitor Roberto Pugliesi Marques, Eny Maria Goloni-Bertollo, Érika Cristina Pavarino

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Paracrine Proangiogenic Function of Human Bone Marrow-Derived Mesenchymal Stem Cells Is Not Affected by Chronic Kidney Disease by Femke C. C. van Rhijn-Brouwer, Bas W. M. van Balkom, Diana A. Papazova, Diënty H. M. Hazenbrink, Anke J. Meijer, Isaac Brete, Vidalmar Briceno, Arjan D. van Zuilen, Raechel J. Toorop, Joost O. Fledderus, Hendrik Gremmels, Marianne C. Verhaar

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Different exercise interventions on quality of sleep in breast cancer survivors—a network meta-analysis of randomized controlled trials by Qi Song, Qi Song, You-kang Zhu, You-kang Zhu, Hai Liu, Hai Liu, Xiao Liu, Xiao Liu, Zhang-dong Jiang, Yu-jia Wang, Yu-jia Wang, Li-yun Xue, Li-yun Xue, Shao-ying Yang, Shao-ying Yang, Xi-fang Liu

“…Notably, a significant proportion of survivors experience sleep disorders following surgery, which can severely impact their quality of life. …”
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Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis by Takenori Suga, Michihiko Usui, Satoru Onizuka, Kotaro Sano, Tsuyoshi Sato, Kohji Nakazawa, Wataru Ariyoshi, Tatsuji Nishihara, Keisuke Nakashima

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Perspectives and Practices of Healthcare Leaders in Supporting Healthcare Worker Well-Being: A Reality Check by Reijmerink IM, van der Laan MJ, Scheele F, Wietasch JKG

“…Iris M Reijmerink,1 Maarten J van der Laan,1 Fedde Scheele,2,3 J K Götz Wietasch4 1Department of Surgery, University Medical Centre Groningen, Groningen, the Netherlands; 2Amsterdam Academic Medical Center, Research in Education, Amsterdam, the Netherlands; 3Athena Institute for Trans-Disciplinary Research, the Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; 4Department of Anaesthesiology, University Medical Centre Groningen, Groningen, the NetherlandsCorrespondence: Iris M Reijmerink, UMCG, Hanzeplein 1, Groningen, 9713GZ, The Netherlands, Tel +316 38 15 85 58, Email i.m.reijmerink@umcg.nlIntroduction: The well-being of healthcare workers (HCWs) is a critical concern. …”
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Biochemical mechanisms and molecular interactions of vitamins in cancer therapy by Abdullahi T. Aborode, Isreal A. Onifade, Mercy M. Olorunshola, Gladys O. Adenikinju, Ibude J. Aruorivwooghene, Adeboboye C. Femi, Osasere Jude-Kelly Osayawe, Abraham Osinuga, Ebenezer A. Omojowolo, Adekunle F. Adeoye, Segun Olapade, Ibrahim O. Adelakun, Ogundepo D. Moyinoluwa, Oluwatosin M. Adeyemo, Godfred Y. Scott, Ruth A. Ogbonna, Emmanuel A. Fajemisin, Omama Ehtasham, Soyemi Toluwalashe, Adetolase A. Bakre, Ridwan O. Adesola, Seto C. Ogunleye, Nnenna R. Anyanwu, Terungwa H. Iorkula

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Impact of PM2.5, relative humidity, and temperature on sleep quality: a cross-sectional study in Taipei by Nguyen Thanh Tung, Yueh-Lun Lee, Wen-Te Liu, Yuan-Chien Lin, Jer-Hwa Chang, Huynh Nguyen Xuan Thao, Hoang Ba Dung, Lam Viet Trung, Tran Phan Chung Thuy, Nguyen Thi Hien, Cheng-Yu Tsai, Chen-Chen Lo, Kang Lo, Kin Fai Ho, Kai-Jen Chuang, Hsiao-Chi Chuang

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Lesiones por animal ponzoñoso, raya de agua dulce: serie de casos by María Alejandra Ríos González, Natalia Sánchez Coronel, Dayra Constanza Rojas Duran, William Mauricio Acero Moreno, Lorena García Agudelo

“…Conclusion: Fluvial stingray causes serious lesions in lower limbs that cause prolonged hospital stays, multiple surgical procedures, large coverage defects that merit the investment of high-tech materials and reconstructive plastic surgery.…”
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Early Recognition and Intervention in SIBlingS at High Risk for Neurodevelopment Disorders (ERI-SIBS): a controlled trial of an innovative and ecological intervention for siblings... by Silvia Annunziata, Giulia Purpura, Giulia Purpura, Elena Piazza, Paolo Meriggi, Gabriele Fassina, Laura Santos, Emilia Ambrosini, Antonella Marchetti, Antonella Marchetti, Federico Manzi, Federico Manzi, Davide Massaro, Davide Massaro, Andrea Luna Tacci, Andrea Luna Tacci, Elisabetta Bolognesi, Simone Agostini, Francesca La Rosa, Alessandra Paola Giulia Pedrocchi, Paola Molina, Anna Cavallini

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[Translated article] Medial tab-type fasciocutaneous flap as an alternative for the management of soft tissue defects of the leg by X. Ríos Garrido, A. De la Rosa, L. Arzuza Ortega, G. Vargas Lievano, J. Molina Gándara, D.A. Tellez Gamarra, C. Medina Monje

“…Results: The patients who underwent surgery with medial tab flap and with conventional flaps healed completely. …”
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STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer by Changli Qian, Gordon J Freeman, Tao Jiang, Ursula Matulonis, Ziying Lin, Hye-Jung Kim, Anniina Färkkilä, Hua Yu, Xin Cheng, Panagiotis A Konstantinopoulos, Antons Martincuks, Joyce F Liu, Qiwei Wang, Liya Ding, Michael J Kearns, Shaozhen Xie, Inga-Maria Launonen, Thomas M Roberts, Jean J Zhao

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DepRescribing inapprOpriate Proton Pump InhibiTors (DROPIT): study protocol of a cluster-randomised controlled trial in Swiss primary care by Stefan Neuner-Jehle, Katharina Tabea Jungo, Sven Streit, Sven Trelle, Nicolas Rodondi, Carole Elodie Aubert, Kristie Rebecca Weir, Enriqueta Vallejo-Yagüe, Samantha Chan, Marie Roumet, Pascal Juillerat, Sofia Carolina Zambrano Ramos, Jennifer Inauen, Angela Edith Schulthess-Lisibach, Renata Vidonscky Lüthold, Clémentine Tombez, Martina Zangger, Flurina Jenal, Yvonne Mattmann, Christof Bieri, Michaela Barbier

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COVID-19 and children with congenital anomalies: a European survey of parents’ experiences of healthcare services by Ingeborg Barisic, Carlos Matias Dias, Amanda Neville, Anna Pierini, Anke Rissmann, Joan K Morris, Judith Rankin, Ester Garne, Anna Latos-Bielenska, Elena Marcus, Anna Jamry-Dziurla, Ljubica Odak, Clara Cavero- Carbonell, Elly Den Hond, Lucas Genard, Ana João Santos, L Renée Lutke, Christina Neergaard Pedersen, Annika Niemann, Lucía Páramo-Rodríguez

“…A third of participants in the UK and Poland reported ‘cancelled or postponed’ surgeries (22/72; 98/266) compared with only 8% in Germany (5/64). …”
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Fractionated robotic radiosurgery for unfavorable nonfunctioning pituitary macroadenoma: 5-year outcomes from a single institution protocol by Akrita Bhatnagar, Monica Pernia Marin, Jonathan W. Lischalk, Min Ji Koh, Siviero Agazzi, Simeng Suy, Brent T. Harris, Susmeeta T. Sharma, Edward Aulisi, Amjad Anaizi, Mohamed H. Khattab, Walter C. Jean, Walter C. Jean, Sean P. Collins, Brian T. Collins

“…There was one in-field failure pathologically confirmed following surgery for pituitary hemorrhage and two radiographically confirmed out-of-field failures in patients with larger tumors (>20 cc).ConclusionsThe treatment of unfavorable nonfunctioning pituitary macroadenoma with 5-fraction robotic radiosurgery provides excellent local control to date, with acceptable toxicity. …”
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