CHI study: protocol for an observational cohort study on ageing and mental health in community-dwelling older adults by Lei Feng, Lieng Hsi Ling, Qiushi Feng, Rachael Zhi Yi Lee, Junhong Yu, Iris Rawtaer, Patrick Finbarr Allen, Zhiming Bao, Jeong Kyu Lee, Chin Tat Lim, Leng Leng Thang, Thet Naing, D Y Wang, Kai Zhen Yap, EH Kua, Rathi Mahendran

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Hypoxic BMSC-derived exosomal miR-210-3p promotes progression of triple-negative breast cancer cells via NFIX-Wnt/β-catenin signaling axis by Meng Wang, Yi Zheng, Qian Hao, Guochao Mao, Zhijun Dai, Zhen Zhai, Shuai Lin, Baobao Liang, Huafeng Kang, Xiaobin Ma

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Only IF/TA in the Histological Evaluation of Post-Reperfusion Baseline Biopsies Correlates With Kidney Transplant Outcome by Quirin Bachmann, Carlos Torrez, Maike Büttner-Herold, Bernhard Haller, Flora Haberfellner, Renate Hausinger, Volker Assfalg, Lutz Renders, Kerstin Amann, Uwe Heemann, Christoph Schmaderer, Stephan Kemmner, Stephan Kemmner

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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? by Marka Crittenden, Sandra Demaria, C Norman Coleman, Jonathan Schoenfeld, Arta Monjazeb, Samir Khleif, Seema Gupta, Andrew Sikora, Zachary Morris, Chandan Guha, Stephen Shiao, Silvia Chiara Formenti, Bhadrasain Vikram, Mansoor M Ahmed

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The clinical features and risk factors of coagulopathy associated with cefoperazone/sulbactam: a nomogram prediction model by Changjing Xu, Junlong Zhu, Kun Tu, Hui Tang, Xinxin Zhou, Qiuyu Li, Kun Chen, Xuping Yang, Yilan Huang

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P53 and Expression of Immunological Markers May Identify Early Stage Thyroid Tumors by Marjory Alana Marcello, Elaine Cristina Morari, Lucas Leite Cunha, Aline Carolina De Nadai Silva, Dirce Maria Carraro, André Lopes Carvalho, Fernando Augusto Soares, José Vassallo, Laura Sterian Ward

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PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways by Xue He⁺, Yanan Cui⁺, Tiao Li, Lijuan Luo, Zihang Zeng, Yiming Ma, Yan Chen

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Managing novel therapies and concomitant medications in chronic lymphocytic leukemia: key challenges by Sofija Kozarac, Jelena Ivanovic, Marko Mitrovic, Kristina Tomic Vujovic, Isidora Arsenovic, Nada Suvajdzic-Vukovic, Nada Suvajdzic-Vukovic, Andrija Bogdanovic, Andrija Bogdanovic, Ana Vidovic, Ana Vidovic, Milena Todorovic-Balint, Milena Todorovic-Balint, Jelena Bila, Jelena Bila, Mirjana Mitrovic, Mirjana Mitrovic, Danijela Lekovic, Danijela Lekovic, Irena Djunic, Irena Djunic, Marijana Virijevic, Marijana Virijevic, Aleksandar Trivic, Aleksandar Trivic, Jelena Micic, Jelena Micic, Darko Antic, Darko Antic

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DNA Copy Number Changes at 8q11–24 in Metastasized Colorectal Cancer by T. E. Buffart, J. Coffa, M. A. J. A. Hermsen, B. Carvalho, J. R. M. van der Sijp, B. Ylstra, G. Pals, J. P. Schouten, G. A. Meijer

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NLRP3 inflammasome-modulated angiogenic function of EPC via PI3K/ Akt/mTOR pathway in diabetic myocardial infarction by Jia-Peng Li, Shu Qiu, Guang-Jie Tai, Yi-Ming Liu, Wei Wei, Meng-Meng Fu, Pan-Qi Fang, Joseph Nicolao Otieno, Tungalag Battulga, Xiao-Xue Li, Ming Xu

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Prevalence of Preoperative Anxiety and Associated Factors Among Surgical Patients: Systematic Review and Meta-Analysis in Ethiopia by Magarsa Lami, Abraham Negash, Jerman Dereje, Ahmed Hiko, Sinetibeb Mesfin, Arsema Gebreyesus, Nano Belama, Nesredin Ahmed Omer, Bikila Balis, Usmael Jibro

“…Background: Preoperative anxiety is commonly characterized as a feeling of tension, apprehension, nervousness, distressing fear, and emotional discomfort preceding surgery. Different studies across the countries indicated an inconsistent prevalence of preoperative anxiety and its associated factors. …”
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SNP-array profiling data from breast cancer patients and healthy women's blood DNA samplesGEO by Rafika Indah Paramita, Sonar Soni Panigoro, Fadilah Fadilah, Septelia Inawati Wanandi, Noorwati Sutandyo

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Exosome miR-199a-5p modulated vascular remodeling and inflammatory infiltration of Takayasu’s arteritis by Shuning Guo, Jiehan Li, Shurui Pang, Jing Li, Xinping Tian

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Ocular inoculation of toad venom: toxic cataract and proteomic profiling by Danni Lyu, Danni Lyu, Shuang Ni, Shuang Ni, Jia Xu, Jia Xu, Sha Zhu, Sha Zhu, Jing-Wei Xu, Jing-Wei Xu, Yixuan Feng, Yixuan Feng, Ce Shi, Ce Shi, Wen Xu, Wen Xu

“…He was diagnosed with a toxic cataract, and underwent phacoemulsification cataract surgery. Anterior capsule, nucleus, and cortex specimens from the patient (designated as PT_CAP, PT_PHACO, and PT_CTX, respectively) and age-related cataract controls (C_CAP, C_PHACO, and C_CTX, respectively) were collected and subjected to 4D label-free quantitative proteomics.ResultsA multitude of differentially expressed proteins (DEPs) were identified in the patient’s lens compared to those in the controls. …”
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Comparative Analysis of the Occurrence and Role of CX3CL1 (Fractalkine) and Its Receptor CX3CR1 in Hemophilic Arthropathy and Osteoarthritis by Piotr Wojdasiewicz, Łukasz A. Poniatowski, Andrzej Kotela, Marta Skoda, Michał Pyzlak, Aleksandra Stangret, Ireneusz Kotela, Dariusz Szukiewicz

“…Tissue specimens including articular cartilage and synovial membrane were similarly collected during surgery and stained immunohistologically using selected antibodies including anti-CX3CR1, anti-CD56, anti-CD68, and anti-CD31. …”
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Four cardiomyopathy patients with a heterozygous DSG2 p.Arg119Ter variant by Takuya Sumida, Shou Ogawa, Shuichiro Higo, Yuki Kuramoto, Ryo Eto, Yoshihiko Ikeda, Congcong Sun, Junjun Li, Li Liu, Tomoka Tabata, Yoshihiro Asano, Mikio Shiba, Yasuhiro Akazawa, Daisuke Nakamura, Takafumi Oka, Tomohito Ohtani, Yasushi Sakata

“…These patients were clinically diagnosed with arrhythmogenic right ventricular cardiomyopathy (Pt-1), dilated cardiomyopathy (DCM) after ventricular septum defect closure surgery (Pt-2), DCM (Pt-3), and end-stage hypertrophic cardiomyopathy (Pt-4). …”
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Correlated factors of posttraumatic growth in patients with colorectal cancer: A systematic review and meta-analysis by Dingyuan Wei, Xue Wang, Mengxing Wang, Jiayan Wang, Fangping Chen, Luyang Jin, Xuemei Xian

“…Correlated factors were identified to be significantly associated with PTG in patients with CRC including demographic factors: residential area (r = 0.13), marital status (r = 0.10), employment status (r = 0.18), education level (r = 0.19), income level (r = 0.16); disease-related factors: time since surgery (r = 0.17), stoma-related complications (r = 0.14), health-promoting behavior (r = 0.46), and sexual function (r = 0.17); psychosocial factors: confrontation coping (r = 0.68), avoidance coping (r = −0.65), deliberate rumination (r = 0.56), social support (r = 0.47), family function (r = 0.50), resilience (r = 0.53), self-efficacy (r = 0.91), self-compassion (r = −0.32), psychosocial adjustment (r = 0.39), gratitude (r = 0.45), stigma (r = −0.65), self-perceived burden (r = −0.31), fear of cancer recurrence (r = −0.45); and quality of life (r = 0.32). …”
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Advancements in 3D printing technologies for personalized treatment of osteonecrosis of the femoral head by Tingting Chen, Lincong Luo, Jiaying Li, Jiamin Li, Tao Lin, Mingrui Liu, Hang Sang, Xinyu Hong, Jiahao Pu, Wenhua Huang

“…Unlike traditional hip replacement surgery, which is often suboptimal for younger patients, 3D printing offers precise localization of necrotic areas and the ability to create personalized implants. …”
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Comorbidities and neurosurgical interventions in a cohort with connective tissue disorders by Ilene S. Ruhoy, Paolo A. Bolognese, Jared S. Rosenblum, Randall A. Dass, Navdeep S. Nayyer, Navdeep S. Nayyer, Jeffrey D. Wood, Jeffrey D. Wood, John B. Biggins, John B. Biggins

“…Of those who elected to undergo surgery (n = 612), 61% required craniocervical fusion (CCF). …”
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Does tocilizumab eliminate inflammation in GCA? A cohort study on repeated temporal artery biopsies by Chiara Marvisi, Francesco Muratore, Carlo Salvarani, Pierluigi Macchioni, Pamela Mancuso, Luigi Boiardi, Stefania Croci, Paolo Giorgi Rossi, Alberto Cavazza, Annibale Versari, Rexhep Durmo, Caterina Ricordi, Martina Bonacini, Giuseppe Malchiodi

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