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3601
Early growth response 1 transcription factor and its context-dependent functions in glioblastoma
Published 2024-08-01“…Early growth response 1 can also induce cell adhesion, migration, chemoresistance against temozolomide, stemness, and self-renewal in glioblastoma cells. …”
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3602
Long Course Hyperbaric Oxygen Stimulates Neurogenesis and Attenuates Inflammation after Ischemic Stroke
Published 2013-01-01“…Several studies have provided evidence with regard to the neuroprotection benefits of hyperbaric oxygen (HBO) therapy in cases of stroke, and HBO also promotes bone marrow stem cells (BMSCs) proliferation and mobilization. …”
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3603
Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer
Published 2017-01-01“…The role of the tumor microenvironment, through tumor-associated macrophages, infiltrating lymphocytes, and cancer stem cells is also discussed, suggesting that these tumor extrinsic factors may help account for the differences in behavior between inflammatory breast cancer and noninflammatory breast cancer. …”
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3604
Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM
Published 2025-01-01“…Abstract Netrin-1 (NTN1) is a laminin-related secreted protein involved in axon guidance and cell migration. Previous research has established a significant connection between NTN1 and nervous system development. …”
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3605
Intercellular communication is crucial in the regulation of healthy aging via exosomes
Published 2025-02-01“…The hallmarks of aging encompass a variety of molecular categories (genomic, telomeric, and epigenetic), organelles (proteostasis, autophagy, and mitochondria), cellular components (including stem cells), systems (such as intercellular communication and chronic inflammation), and environmental factors (dysbiosis and nutrient sensing). …”
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3606
ENL mutation and AML: a new model that reveals oncogenic condensate's function in leukemogenesis
Published 2025-01-01“…This mutant ENL forms condensates in hematopoietic stem/progenitor cells at the genomic loci of key leukemogenic genes, including Meis1 and Hoxa cluster genes, and disrupting condensate formation via mutagenesis impairs its chromatin and oncogenic function. …”
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3607
Lithium-doped calcium silicate cement regulates the immune microenvironment and promotes M2 macrophage polarization for enhancing bone regeneration
Published 2025-01-01“…In vitro assays revealed that the LiCS cement enhanced the proliferation, adhesion, and spread of Wharton’s jelly mesenchymal stem cells (WJMSCs). Additionally, Li-CS cement exhibited remarkable immunomodulatory properties by reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines, promoting the polarization of macrophages towards the M2 phenotype. …”
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3608
Effect of fecal microbiota transplantation on ulcerative colitis model in rats: The gut–brain axis
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3609
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3610
Long-Term Stability and Osteogenic Activity of Recycled Polysulfone-Calcium Silicate Bone Implants In Vitro
Published 2025-01-01“…We evaluated the phase, morphology, weight loss, and three-point bending strength of the PSF-based composites after they were soaked in dynamic simulated body fluid (SBF) at pH levels of 7.4 and 5.0 for up to 12 months. Human mesenchymal stem cells (hMSCs) were utilized to assess the osteogenic activity of these composites. …”
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3611
Improved constructs for bait RNA display in a bacterial three-hybrid assay
Published 2025-01-01“…To support correct folding of hybrid bait RNAs, we have explored the use of a highly stable stem (“GC clamp”) to isolate regions of a hybrid RNA as discrete folding units. …”
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3612
RESPONSE OF LOCAL ORANGE TRANSPLANTS TO BIO AND ORGANIC FERTILIZERS AND SPRAYING WITH MORINGA LEAVES EXTRACT
Published 2025-01-01“…Experimental results showed that adding two types of bacteria (A4) and buffalo manure at a level of 500 g.soil-1 (B2) and spraying moringa extract at a concentration of 40 g.L-1 (M2) as interaction treatment A4B2M2 produced best results in shoot number, stem diameter, leaf potassium and iron percent %, and epidermal and spongy cells layers thickness, (25.00, 41.00) shoot.plant-1, (14.247, 5.283) mm, (2.980, 2.885) %, (215.8, 220.7) mg.kg-1 for two growing seasons, respectively, and (48.60, 108.4) micrometer, respectively compared to control treatment. …”
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3613
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3614
Application of Mesoporous Silica Nanoparticle-Chitosan-Loaded BMP-2 in the Repair of Bone Defect in Chronic Osteomyelitis
Published 2022-01-01“…Bone marrow mesenchymal stem cells (BMSCs) were purchased and cultivated to detect the osteogenesis of chitosan-MSN (Chi-MSN) and polylactic acid glycolic acid (PLGA) delivery system. …”
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3615
Management of Anal Fistula with Crohn's Disease
Published 2025-01-01“…In addition to biologics, molecular target drugs and even regenerative medicine using mesenchymal stem cells have been introduced to further expand the treatment options for consideration by medical personnel. …”
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3616
CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting.
Published 2024-01-01“…Furthermore, we noted an increased percentage of CMML CD34+ stem and progenitor cells expressing CD116 and CD131 in all CBL mutant cases and increased CD116 receptor density compared to healthy controls, similar to CMML overall. …”
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3617
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3618
Therapeutic molecules for multiple human diseases identified from pigeon pea (Cajanus cajan L. Millsp.) through GCâMS and molecular docking
Published 2017-12-01“…Molecular mechanism behind the therapeutic potential of pigeon pea over the human diseases such as rheumatoid arthritis, breast cancer, type II diabetes, malaria, measles and sickle cell disease were revealed through docking of GCâMS identified phyto-compound ligands with candidate disease proteins. …”
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3619
MRD-driven phase 2 study of daratumumab, carfilzomib, lenalidomide, and dexamethasone in newly diagnosed multiple myeloma
Published 2025-02-01“…MRD-positive transplant-eligible patients (n = 8, group B) underwent autologous stem cell transplantation, with 62.5% converting to MRD-negative at 10−5 (37.5% at 10−6) posttransplant. …”
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3620
Epoetin-alfa-induced osteogenesis in the bone organoid model
Published 2024-12-01“…Materials and Methods: The study was conducted on human mesenchymal stem cells (hMSC) and trabecular bone organoids (TBO). …”
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