Iron Chelation Therapy in Myelodysplastic Syndromes by Emanuela Messa, Daniela Cilloni, Giuseppe Saglio

“…Myelodysplastic syndromes (MDS) are a heterogeneous disorder of the hematopoietic stem cells, frequently characterized by anemia and transfusion dependency. …”
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Genetic Associations in Acquired Immune-Mediated Bone Marrow Failure Syndromes: Insights in Aplastic Anemia and Chronic Idiopathic Neutropenia by Irene Mavroudi, Helen A. Papadaki

“…However, in immune-mediated bone marrow failure syndromes, such as acquired aplastic anemia and chronic idiopathic neutropenia, in which the pathophysiology results from a myelosuppressive bone marrow microenvironment mainly due to the presence of activated T lymphocytes, leading to the accelerated apoptotic death of the hematopoietic stem and progenitor cells, such genetic associations have been very limited. …”
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Effects of melatonin on planaria head regeneration are dependent on both timing and duration of exposure by Simon C. Beeching, Hanna E. Ruland, Katelyn M. Sparks

“…Head regeneration in planaria is a remarkable phenomenon in which stem cells (neoblasts) migrate to the wound site, proliferate, then differentiate into all functional tissue types within days of injury. …”
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Biologic Augmentation of the Ulnar Collateral Ligament in the Elbow of a Professional Baseball Pitcher by James K. Hoffman, Nicole M. Protzman, Amit D. Malhotra

“…A construct comprising a dermal allograft, platelet rich plasma (PRP), and mesenchymal stem cells (MSCs) has been shown to successfully improve healing in the rotator cuff. …”
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Diagnostic and Treatment Challenges of Paroxysmal Nocturnal Hemoglobinuria in Uganda by Boniface Amanee Elias Lumori, Daniel Muyanja

“…Paroxysmal nocturnal hemoglobinuria (PNH) is a very rare disorder of the hematopoietic stem cells which is often underdiagnosed. Its incidence is about 5 cases per million inhabitants in a year, and currently, there are only 1610 patients in the International PNH Registry. …”
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Low-Dose Taxol Promotes Neuronal Axons Extension and Functional Recovery after Spinal Cord Injury by Baoguo Liu, Sumei Liu, Dejun Sun

“…In our study, we systematically investigated the differentiation of neural stem cells (NSCs) in vitro and functional recovery in injured rats in vivo following Taxol treatment. …”
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E-cadherin/CD34 double immunostaining in placental diagnosis by Jerzy Stanek

“…It also highlights the basement membranes of syncytiotrophoblastic cells which, in conjunction with endothelial staining, is helpful in the diagnosis of widening thereof in distal villous hypomaturity. …”
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Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway by Xin Ma, Meng Li, Yuanyuan Zhang, Tingting Xu, Xinchen Zhou, Mengqi Qian, Zhiren Yang, Xinyan Han

“…A. muciniphila was identified as a key strain in FMT to promote the proliferation and differentiation of intestinal stem cells by mediating the Wnt/β-catenin signaling pathway.…”
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Strontium–Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment by Wenxiu Yuan, Jiaqi Liu, Zhenzhen Zhang, Chengxinyue Ye, Xueman Zhou, Yating Yi, Yange Wu, Yijun Li, Qinlanhui Zhang, Xin Xiong, Hengyi Xiao, Jin Liu, Jun Wang

“…Interestingly, this system is specifically oriented towards synovium-derived stem cells. The insight into trace element-driven, site-specific miRNA selectively loading in SMSC-EXOs proposes a promising therapeutic enhancement strategy for TMJOA.…”
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Perspectives on the use of decellularized/devitalized and lyophilized human perinatal tissues for bone repair: Advantages and remaining challenges by Lauriana Solecki, Mathilde Fenelon, Halima Kerdjoudj, Roberta Di Pietro, Gianmarco Stati, Camille Gaudet, Eugenie Bertin, Jeremie Nallet, Aurélien Louvrier, Thomas Gualdi, Jessica Schiavi-Tritz, Florelle Gindraux

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Effect of Opioid on Adult Hippocampal Neurogenesis by Yue Zhang, Horace H. Loh, Ping-Yee Law

“…Many studies focus on the factors that regulate proliferation and fate determination of adult neural stem/progenitor cells, including addictive drugs such as opioid. …”
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Plucked Human Hair Shafts and Biomolecular Medical Research by Kevin Schembri, Christian Scerri, Duncan Ayers

“…The plucked hair shaft offers such advantages. The use of stem cells found in hair follicles cells is gaining momentum in the field of regenerative medicine. …”
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Cannabigerol and cannabichromene in Cannabis sativa L. by Zagožen Marjeta, Čerenak Andreja, Kreft Samo

“…Cannabinoid CBC has also shown anti-inflammatory effects and reduced hypermobility in the gut and has displayed potential in vitro effect on adult neural stem progenitor cells. CBC also exerts modest analgesic properties in rodents, as well as anti-fungal, anti-bacterial, pro-apoptotic, and anti-proliferative effects in tumor cells.…”
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Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration by H Nilofer Farjana, G. Mohan Valiathan

“…CQ can differentiate human-derived mesenchymal stem cells into osteoblast and regenerate bone. This review elaborates on the use of CQ as a bioactive compound for periodontal regeneration.…”
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ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation by Jiaxing Zhang, Jiaxing Zhang, Gang Wang, Jie Liu, Futian Tang, Song Wang, Yumin Li, Yumin Li

“…However, its role across different cancer types is not well understood.MethodsUtilizing multi-omics data, we comprehensively evaluated ITGA4’s expression, clinical relevance, diagnostic and prognostic value, functions, mutations, and methylation status, along with its impact on immunity, mismatch repair (MMR), heterogeneity, stemness, immunotherapy responsiveness, and drug resistance in pan-cancer, with partial validation in gastric cancer (GC) using transcriptomic analysis, single-cell data, western blot (WB), wound-healing assay, flow cytometry and immunohistochemistry (IHC). …”
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Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms by Esther Natalie Oliva, Shien Guo, Jennifer Lord-Bessen, Aylin Yucel, Roberto Latagliata, Massimo Breccia, Giuseppe A. Palumbo, Grazia Sanpaolo, Marta Riva, Valeria Santini, Uwe Platzbecker, Guillermo Garcia-Manero, Pierre Fenaux, Christopher G. Pelligra

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Screening potential antileukemia ingredients from sweet potato: integration of metabolomics analysis, network pharmacology, and experimental validation by Lianling Xu, Lianling Xu, Kaixuan Zeng, Kaixuan Zeng, Zuoyue Duan, Zuoyue Duan, Jing Liu, Yan Zeng, Miao Zhang, You Yang, Qulian Guo, Yanling Jin, Wenjun Liu, Ling Guo

“…Finally, the anti-leukemia effect of cynaroside was further confirmed through in vivo experimental validation.ResultsFirstly, the flavonoid content of stem, leaves, flesh, and peel from 13 sweet potato cultivars was examined. …”
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Ganoboninketal C from Ganoderma boninense improves the efficacy of CDDP-based chemotherapy through inhibiting translesion DNA synthesis by Xiaolu Ma, Fei Yang, Ke Ma, Hongyan Shen, Junjie Han, Kai Wang, Yeran Yang, Jiawei Zhu, Ruiyuan An, Qilin Wang, Tie-Shan Tang, Bo Zhou, Hongwei Liu, Caixia Guo

“…Moreover, 26-3 can significantly sensitize tumor cells to CDDP killing and reduce the proportion of cancer stem cells in AGS and promote apoptosis after CDDP exposure. …”
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Modeling and correction of protein conformational disease in iPSC-derived neurons through personalized base editing by Colin T. Konishi, Nancy Mulaiese, Tanvi Butola, Qinkun Zhang, Dana Kagan, Qiaoyan Yang, Mariel Pressler, Brooke G. Dirvin, Orrin Devinsky, Jayeeta Basu, Chengzu Long

“…We developed HEK293T and induced pluripotent stem cell (iPSC) models of FENIB, harboring a patient-specific pathogenic SERPINI1 variant or stably overexpressing mutant neuroserpin fused to GFP (MUT NS-GFP). …”
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Effectiveness of a Novel Liposomal Methylglyoxal–Tobramycin Formulation in Reducing Biofilm Formation and Bacterial Adhesion by Wed Alluhaim, Manal M. Alkhulaifi, Raghad R. Alzahrani, Bahauddeen M. Alrfaei, Alaa Eldeen B. Yassin, Majed F. Alghoribi, Ahlam M. Alsaadi, Ahmed I. Al-Asmari, Ahmed J. Al-Fahad, Rizwan Ali, Naif M. Alhawiti, Majed A. Halwani

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