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The role of ultrasound combined with water bath in the establishment of animal models of rat urethral stricture
Published 2025-01-01“…The surgical groups underwent urethral injury induced by recombinant transforming growth factor-β1 (TGF-β1) solution, followed by the random selection of one surgical group (n = 6) to receive treatment with mesenchymal stem cell (MSC) exosomes. High-frequency ultrasonography using a GE E10 device combined with a water bath method was employed to evaluate the urethral conditions of all rats. …”
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3442
SAP30, a novel autophagy regulatory gene in neuroblastoma
Published 2025-03-01“…Autophagy is vital for neuronal development, balance, and differentiation of neural stem cells into mature neurons. However, the intricate mechanisms governing autophagy and the pivotal genes orchestrating its regulation in NB remain largely elusive. …”
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3443
Occupational adjustments and work ability of young adult cancer survivors: results from the AYA-Leipzig study
Published 2024-12-01“…Younger age (< 30) and stem cell transplant were associated with a lower benefit of support from colleagues (R2 = 0.077). …”
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3445
Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results
Published 2025-01-01“…Ida Ayu Manik Partha Sutema,1,2 Irma Rahayu Latarissa,1,3 I Gusti Ayu Rai Widowati,2 Cynthia Retna Sartika,1,4 Ni Wayan Eka Ciptasari,5 Keri Lestari1,3,6 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Clinical Pharmacy Study Program, Faculty of Health Sciences, Bali International University, Denpasar, Indonesia; 3Medication Therapy Adherence Clinic (MTAC), Universitas Padjadjaran, Sumedang, Indonesia; 4PT Prodia StemCell Indonesia, Central Jakarta, Jakarta, Indonesia; 5Ngoerah Sun Wellness and Aesthetic Center, Prof. …”
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3447
A novel strategy for the protective effect of ginsenoside Rg1 against ovarian reserve decline by the PINK1 pathway
Published 2025-12-01“…Protein expression levels in the PINK1/Parkin pathway were assessed, and molecular docking and PINK1 mutant analyses were conducted to identify potential targets.Results Ginsenoside Rg1 significantly mitigated ovarian reserve decline, enhancing offspring quantity and quality, increasing the levels of ecdysteroids, preventing ovarian atrophy, and elevating germline stem cell numbers in aged Drosophila. Ginsenoside Rg1 improved superoxide dismutase, catalase activity, and gene expression while reducing reactive oxygen species levels. …”
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3449
Unveiling the molecular and cellular links between obstructive sleep apnea-hypopnea syndrome and vascular aging
Published 2025-01-01“…This review examines the molecular and cellular features common to both OSAHS and VA, highlighting decreased melatonin secretion, impaired autophagy, increased apoptosis, increased inflammation and pyroptosis, increased oxidative stress, accelerated telomere shortening, accelerated stem cell depletion, metabolic disorders, imbalanced protein homeostasis, epigenetic alterations, and dysregulated neurohormonal signaling. …”
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3450
Identification of circRNA/miRNA/mRNA regulatory network involving (+)-catechin ameliorates diabetic nephropathy mice
Published 2022-05-01“…The expanded network of proteins interacting with these 5 genes shows that the TGF-β signaling pathway, signaling pathways regulating pluripotency of stem cell, fat digestion and absorption, and PPAR signaling pathway was highly enriched. …”
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3454
Matrix vesicle-inspired delivery system based on nanofibrous chitosan microspheres for enhanced bone regeneration
Published 2025-02-01“…Additionally, the nanofibrous network of NCMP mimics the architecture of natural extracellular matrix (ECM), creating an optimal niche for the active adhesion of stem cells to its surface, exhibiting good biocompatibility, immunoregulation, and osteogenic performance. …”
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3455
Uptake kinetics and distribution of flupyrimin by rice (Oryza sativa L.): Effects of subcellular fractionation and soil factors
Published 2025-02-01“…The hydroponic experiment indicated that flupyrimin was easily taken up by rice roots via a symplastic passive diffusion process and was mainly distributed in the cell soluble fractions (50.6 %-88.0 %). Compared with transportation from the roots to the stems, flupyrimin was ultimately transported from the stems to the leaves with a greater translocation factor (TF) (TFLeave/Stem = 27.8 > TFStem/Root = 3.1). …”
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Inflammation as a Driver of Clonal Evolution in Myeloproliferative Neoplasm
Published 2015-01-01“…Moreover, JAK2V617F mutated hematopoietic stem and progenitor cells are resistant to inflammation, and this gives the neoplastic clone a selective advantage allowing for its clonal expansion. …”
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3459
MicroRNAs Expression Profile in MN1-Altered Astroblastoma
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3460
Integrating melt electrospinning writing and microfluidics to engineer a human cardiac microenvironment for high-fidelity drug screening
Published 2025-03-01“…Although human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) and the engineered heart organoid have been used for drug screening and mimicking disease models, they are always limited by the immaturity and lack of functionality of the cardiomyocytes. …”
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