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3201
Non-coding RNAs participate in interactions between senescence and gastrointestinal cancers
Published 2025-01-01“…., telomere attrition and stem cell exhaustion. These relationships are characterized by both agonistic and antagonistic elements, but the existence of an intricate dynamic balance remains unknown. …”
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3202
Characterization of Thermal Properties of Highland Bamboo Fibers
Published 2022-01-01“…The surface appearance of the cell wall and microfibril aggregates were changed by alkali treatment. …”
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3203
Secondary Primary Malignancies in Multiple Myeloma: An Old Nemesis Revisited
Published 2012-01-01“…High-dose chemotherapy with autologous stem cell support became widely accepted for myeloma in the 1990s. …”
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3204
Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case report
Published 2025-01-01“…Capillary leak syndrome (CLS) represents a critical complication arising from allogeneic hematopoietic stem cell transplantation (allo-HSCT). The prognosis for CLS remains considerably constrained. …”
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3205
Treatment of Acute Graft-versus-Host Disease in Liver Transplant Recipients
Published 2021-01-01“…We report on two patients who developed aGvHD after liver transplantation who were treated with ruxolitinib, a novel Janus kinase 1/2 (JAK) inhibitor that has been shown to improve outcomes in steroid refractory cases of aGvHD after allogenic hematopoietic stem cell transplantation. We reviewed the literature to discuss various therapeutic options currently available for aGvHD after liver transplantation.…”
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3206
Venetoclax and Azacitidine Combination is an Effective Salvage Regimen for Fit Patients with IDH-2-mutated Acute Myeloid Leukemia Refractory to Conventional Induction Chemotherapy
Published 2024-12-01“…Moreover, fit patients with AML who fail to respond to conventional induction chemotherapy represent a high-risk group in whom the only potential cure is allogeneic stem cell transplantation (AlloSCT), which is ideally performed after achievement of complete remission following treatment with a salvage regimen. …”
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3207
The biological and functional restoration of spinal cord injury
Published 2024-12-01“…Restoration of the anatomical structure and microenvironment of the damaged region can be obtained by molecular drug modulation, neuroprotection, neuroregeneration, stem cell therapy, and biomaterial‐based tissue engineering. …”
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3208
Mechanism and Treatment Strategy of Osteoporosis after Transplantation
Published 2015-01-01“…Using the signaling pathway or implantation bone marrow stem cell provides a novel direction for the treatment of OP, especially OP after transplantation. …”
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3209
Advancements in Antioxidant-Based Therapeutics for Spinal Cord Injury: A Critical Review of Strategies and Combination Approaches
Published 2024-12-01“…This review provides a comprehensive and critical evaluation of recent advancements in antioxidant-based therapeutic strategies for SCI, including natural compounds, RNA-based therapies, stem cell interventions, and biomaterial applications. …”
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3210
CXCL14 in prostate cancer: complex interactions in the tumor microenvironment and future prospects
Published 2025-01-01“…However, previous pan-cancer studies have reported inconsistencies regarding the effects of CXCL14 on tumors, particularly concerning its expression levels in tumor tissues and its influence on various phenotypes of cancer cells. This variability is believed to stem from the context-dependent nature of CXCL14, as different sources of CXCL14 and its secretion within distinct tumor microenvironments may mediate diverse biological effects. …”
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3211
Genome-wide analysis of sugar transporter gene family in Erianthus rufipilus and Saccharum officinarum, expression profiling and identification of transcription factors
Published 2025-01-01“…Sugar, the primary product of photosynthesis, is a vital requirement for cell activities. Allocation of sugar from source to sink tissues is facilitated by sugar transporters (ST). …”
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3212
RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models
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3213
Causal Association Between Obstructive Sleep Apnea and Migraine: A Bidirectional Mendelian Randomization Study
Published 2025-01-01“…Yu-Pei Wang,1,* Hui-Xia Wei,2,* Yuan-Yuan Hu,3 Chao Zhang,4 Yu-Ming Niu3– 5 1Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China; 2Department of Anesthesiology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People’s Republic of China; 3Department of Stomatology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, People’s Republic of China; 4Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China; 5Hubei Key Laboratory of Embryonic Stem Cell Research, Hubei Provincial Clinical Research Center for Umbilical Cord Blood Hematopoietic Stem Cells, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yu-Ming Niu, Department of Stomatology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, People’s Republic of China, Tel +86 13581370999, Email niuyuming@yeah.net Chao Zhang, Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China, Email zhangchao0803@126.comObjective: Patients with obstructive sleep apnea (OSA) frequently suffer from migraine, however the causal relationship between OSA and migraine is unknown. …”
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3214
Association between Polyunsaturated Fatty Acid Profile and Bronchial Inflammation in Bronchiolitis Obliterans
Published 2023-01-01“…Bronchiolitis obliterans (BO) is a chronic lung disease, which occurs after an insult to the lower airways, in particular after airway infections or after stem cell transplantation, and which results in persistent inflammation. …”
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3215
Spatial Transcriptome and Single Nucleus Transcriptome Sequencing Reveals Tetrahydroxy Stilbene Glucoside Promotes Ovarian Organoids Development Through the Vegfa‐Ephb2 Pair
Published 2025-01-01“…Here, plant‐derived compounds are screened for in vitro activity upon ovarian organoids derived from feeder‐free female germline stem cells. Tetrahydroxy stilbene glucoside (TSG) is found to promote the development of ovarian organoids. …”
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3216
Gain-of-Function Mutations in STAT1: A Recently Defined Cause for Chronic Mucocutaneous Candidiasis Disease Mimicking Combined Immunodeficiencies
Published 2017-01-01“…Genetic analysis revealed a predefined heterozygous gain-of-function mutation (GOF) (c.1154 C>T, p.Thr385Met) in the gene coding STAT1 molecule. Hematopoietic stem cell transplantation (HSCT) was planned because of severe recurring infections. …”
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3217
Discoidin domain receptor 2 is an important modulator of BMP signaling during heterotopic bone formation
Published 2025-01-01“…In addition, Ddr2 deficiency attenuates HO in mice expressing the ACVR1 mutation associated with human fibrodysplasia ossificans progressiva. In cells migrating into BMP2 implants, DDR2 is co-expressed with GLI1, a skeletal stem cell marker, and DDR2/GLI1-positive cells participate in BMP2-induced bone formation where they contribute to chondrogenic and osteogenic lineages. …”
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3218
Nanodrug‐Engineered Exosomes Achieve a Jointly Dual‐Pathway Inhibition on Cuproptosis
Published 2025-01-01“…A Cu‐chelator (Clioquinol, CQ) polydopamine (PDA)‐modified stem cell exosome loaded with siRNA‐FDX1, named EXOsiFDX1‐PDA@CQ, is designed to efficiently inhibit the two cuproptosis pathways. …”
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3219
Radioprotective Effects of Vitis vinifera L. Seed against Radiation-Induced Short-Term Memory Loss in Young Adult Wistar Rats
Published 2024-10-01“…This issue primarily arises from ionizing radiation generating reactive oxygen species, contributing to chronic oxidative stress that can damage brain cells. While dose fractionation, intensity-modulated radiotherapy, and neural stem cell transplantation have demonstrated limited effectiveness, natural plant antioxidants offer a promising alternative. …”
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3220
Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization
Published 2025-01-01“…Islet transplantation and more recently stem cell-derived islets were shown to successfully re-establish glycemic control in people with type 1 diabetes under immunosuppression. …”
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