Optimized gene transduction in human lung organoids: A high-efficiency method for advanced research applications by Jasmin Khateeb, Jady Liang, Yuchong Li, Thenuka Thanabalasingam, Julie Khang, Mirjana Jerkic, Giovanna Pellecchia, Bhooma Thiruv, Ya-Wen Chen, Ori Rotstein, Arthur S. Slutsky, Haibo Zhang

“…Abstract Human induced pluripotent stem cell (iPSC)-derived lung organoids, engineered to carry targeted genes, offer a robust platform for investigating mechanistic insights in lung research. …”
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Circ_0044516 Regulates miR-136/MAT2A Pathway to Facilitate Lung Cancer Development by Yue-Wei Chen, Qiu-Rong Du, Yu-Juan He, Wen-Shu Chen, Wen-Yang Jiang, Qi Gui, Cheng-Cheng Xu, Wei Wang, Hong-Yun Cheng

“…We also found that cancer stem cell properties were restrained by silencing circ_0044516 in A549 and SPC-A1 cells. …”
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In Vitro Evaluation of Bioactivity of Chemically Deposited Hydroxyapatite on Polyether Ether Ketone by D. Almasi, S. Izman, M. Sadeghi, N. Iqbal, F. Roozbahani, G. Krishnamurithy, T. Kamarul, M. R. Abdul Kadir

“…The mesenchymal stem cell proliferation result showed better cells proliferation on the treated layer in comparison with untreated PEEK. …”
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Effects of exercise intensity and diet on cardiac tissue structure and FGF21/β-Klotho signaling in type 2 diabetic mice: a comparative study of HFD and HFD + STZ induced type 2 dia... by Sevda Moharamzadeh, Majid Kashef, Mojtaba Salehpour, Meysam Torabi, Samira Vesali, Zakieh Samsonchi, Ensiyeh Hajizadeh-Saffar

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Vitamin A: A Key Inhibitor of Adipocyte Differentiation by Manal A. Malibary

“…Nevertheless, the functional role of RA in early tissue development and stem cell differentiation, including in adipose tissue, remains unclear. …”
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Hemorrhagic Spinal Schwannoma in Thoracolumbar Area with Total Paraplegia by Ahmad Jabir Rahyussalim, Rizky Priambodo Wisnubaroto, Tri Kurniawati, Alfariq Senja Belantara Latsarizul, Nuryati Chairani

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Cellular Plasticity in Prostate Cancer Bone Metastasis by Dima Y. Jadaan, Mutaz M. Jadaan, John P. McCabe

“…An electronic search was performed using PubMed for studies that have examined the differential expression of epithelial, mesenchymal, and stem cell markers in human PC bone metastasis tissues. …”
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Latest Approved Therapies for Metastatic Melanoma: What Comes Next? by Farid Menaa

“…Eventually, multidisciplinary approaches are still requested (e.g., genomics for personalized medicine, nanomedicine to overcome low free-drug bioavailability and targeting, systematic search of “melanoma stem cells” to enhance the prognosis and develop more valuable theranostics). …”
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Prenatal Brain Damage in Preeclamptic Animal Model Induced by Gestational Nitric Oxide Synthase Inhibition by Begoña Pellicer, Sonia Herraiz, Antonio Leal, Carlos Simón, Antonio Pellicer

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Role of Cold atmospheric plasma in cancer management by Shrikant B. Mali

“…Cold atmospheric plasma (CAP) has shown potential in treating skin diseases and chronic wounds, reducing tumor-cell viability and stimulating stem-cell proliferation. …”
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Immune infiltrate populations within distinct tumor immune microenvironments predictive of immune checkpoint treatment outcome by Brian Z Ring, Catherine T. Cronister, Huijun Z. Ring, Douglas T. Ross, Robert S. Seitz

“…We have previously validated signatures predictive of checkpoint inhibitor efficacy which distinguish immunomodulatory, mesenchymal stem-like, and mesenchymal phenotypes. Here we use twenty tumor types (7162 samples) to identify potentially conserved immune biology within these TIME spaces, genes co-expressed across distinct cell types involved these immune processes, and the association of these signatures with ICI response. …”
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Mitotic chromatin marking governs the segregation of DNA damage by Juliette Ferrand, Juliette Dabin, Odile Chevallier, Matteo Kane-Charvin, Ariana Kupai, Joel Hrit, Scott B. Rothbart, Sophie E. Polo

“…We propose that this mechanism may help preserve the integrity of stem cell compartments during asymmetric cell divisions.…”
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Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models by Wenhui Li, Xianyue Jiang, Wuke Wang, Liya Hou, Runze Cai, Yongqian Li, Qiuxi Gu, Qinchang Chen, Peixiang Ma, Jin Tang, Menghao Guo, Guohui Chuai, Xingxu Huang, Jun Zhang, Qi Liu

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Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon by Jaime Cofre, Eliana Abdelhay

“…On the other hand, “cancer disease” is the representation of an abnormal state of the cell that might happen in the stem cells of an adult person, in which the mechanism for joint gene regulating of differentiation, proliferation, cell invasion, and migration could be reactivated in an entirely inappropriate context.…”
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Histomorphometric Evaluation of Superovulation Effect on Follicular Development after Autologous Ovarian Transplantation in Mice by Amin Tamadon, Alireza Raayat Jahromi, Farhad Rahmanifar, Mohammad Ayaseh, Omid Koohi-Hosseinabadi, Reza Moghiminasr

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Brentuximab Vedotin Treatment for Primary Refractory Hodgkin Lymphoma by Hung-Bo Wu, Shyh-An Yeh, Huei-Yung Chen

“…With intensive salvage chemotherapy and autologous stem cell transplantation, the long-term remission rate for these patients was only 30%, but more selective treatments with higher therapeutic index are needed. …”
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Advancing cancer therapy with custom-built alternating electric field devices by Isobel Jobson, Nguyen T. N. Vo, Edward Kujawinski, Chris Denning, Snow Stolnik, Veeren M. Chauhan, Frankie Rawson

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MSC-EVs and UCB-EVs promote skin wound healing and spatial transcriptome analysis by Ruonan Li, Haotian Wang, Xiaolong Wang, Yanbin Yang, Kai Zhong, Xuemei Zhang, Heping Li

“…This study investigated the effect of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) isolated from umbilical cord blood and human umbilical cord plasma-derived extracellular vesicles (UCB-EVs) on wound healing and scar formation reduction. …”
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Using the Neurofibromatosis Tumor Predisposition Syndromes to Understand Normal Nervous System Development by Cynthia Garcia, David H. Gutmann

“…Development is a tightly regulated process that involves stem cell self-renewal, differentiation, cell-to-cell communication, apoptosis, and blood vessel formation. …”
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Performance of Lac Insect Kerria lacca Kerr on Bushy Host Flemingia semialata (Roxb.) by P. Bhagyapriya, S. R. Koteswara Rao, Sanyasidhurua, D. Ramesh

“…., sex ratio (% of male insects), density at crop maturity (Number per square cm) were recorded high at lower stem portion of the host plant F. semialata compared to upper and middle stem portions. …”
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