Iron Chelation Therapy in Myelodysplastic Syndromes by Emanuela Messa, Daniela Cilloni, Giuseppe Saglio

“…Myelodysplastic syndromes (MDS) are a heterogeneous disorder of the hematopoietic stem cells, frequently characterized by anemia and transfusion dependency. …”
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Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon by Jaime Cofre, Eliana Abdelhay

“…On the other hand, “cancer disease” is the representation of an abnormal state of the cell that might happen in the stem cells of an adult person, in which the mechanism for joint gene regulating of differentiation, proliferation, cell invasion, and migration could be reactivated in an entirely inappropriate context.…”
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zIncubascope: Long-term quantitative imaging of multi-cellular assemblies inside an incubator. by Anirban Jana, Naveen Mekhileri, Adeline Boyreau, Aymerick Bazin, Nadège Pujol, Kevin Alessandri, Gaëlle Recher, Pierre Nassoy, Amaury Badon

“…We exemplify the capabilities of our system by investigating human induced pluripotent stem cells (hiPSCs) enclosed in spherical capsules, hiPSCs in tubular capsules and yeast cells in spherical capsules. …”
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FoxA1 knockdown promotes BMSC osteogenesis in part by activating the ERK1/2 signaling pathway and preventing ovariectomy-induced bone loss by Lijun Li, Renjin Lin, Yang Xu, Lingdi Li, Zhijun Pan, Jian Huang

“…Using a mouse model in which the ovaries were surgically removed, researchers reported that suppressing the FOXA1 gene in bone marrow stem cells (BMSCs) prevented the loss of bone density caused by ovariectomy. …”
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Corrigendum: Lack of Helios during neural development induces adult schizophrenia-like behaviors associated with aberrant levels of the TRIF-recruiter protein WDFY1 by Anna Sancho-Balsells, Anna Sancho-Balsells, Anna Sancho-Balsells, Anna Sancho-Balsells, Veronica Brito, Veronica Brito, Veronica Brito, Veronica Brito, Belissa Fernández, Belissa Fernández, Belissa Fernández, Belissa Fernández, Mónica Pardo, Mónica Pardo, Mónica Pardo, Mónica Pardo, Marco Straccia, Marco Straccia, Marco Straccia, Marco Straccia, Marco Straccia, Silvia Ginés, Silvia Ginés, Silvia Ginés, Silvia Ginés, Jordi Alberch, Jordi Alberch, Jordi Alberch, Jordi Alberch, Jordi Alberch, Isabel Hernández, Belén Arranz, Josep M. Canals, Josep M. Canals, Josep M. Canals, Josep M. Canals, Josep M. Canals, Albert Giralt, Albert Giralt, Albert Giralt, Albert Giralt, Albert Giralt

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Effects of Electroacupuncture at Zusanli and Quchi on Neurological Function Recovery in Rats with Cerebral Infarction by Jiangcong HONG, Yingzheng WANG, Guangwen WU, Yulong ZOU

“…Therefore, the electroacupuncture treatment can also promote the proliferation and migration of neural stem cells but not induce a great change in the differentiation.…”
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Corps embryoïdes : biologie moléculaire et cellules vivantes by Noémie Merleau-Ponty

“…The human embryo must first be inserted into a kinship—then detached from that kinship: one begins humanising it, then halts the humanising process to metamorphose it in a lineage of human embryonic stem cells. Embryoid bodies are constructed laboratory materials that are also steeped in emotions and profit margins, pasts and futures, in the recesses of which beats the organic pulse of the living.…”
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Comparative analysis of pediatric SHH medulloblastoma DAOY spheres and adherent monolayers: implications for medulloblastoma research by Jana Klementová, Šárka Jarošová, Irina Danilová, Markéta Farníková, Josef Novotný, Marie Davídková, Martina Zíková

“…Our findings demonstrate that DAOY spheres express markers for both neural stem cells, such as CD133 (PROM1), and differentiated neurons, exemplified by MAP2. …”
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Development of the inner ear and regeneration of hair cells after hearing impairment by Xin Bing, Chengcheng Liu, Xue Cao, Chengzhilin Li, Xiaochen Gao, Fangyuan Zhu, Xinhao Wu, Na Guo, Houyang Hu, Ming Xia, Miaoqing Zhao

“…In recent years, the protection of drug-related ototoxicity, inner ear stem cells, gene therapy, new materials, and signal regulation have become important ways to develop regeneration strategies of HCs. …”
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Non-Drug and Non-Invasive Therapeutic Options in Alzheimer’s Disease by Alina Simona Șovrea, Adina Bianca Boșca, Eleonora Dronca, Anne-Marie Constantin, Andreea Crintea, Rada Suflețel, Roxana Adelina Ștefan, Paul Andrei Ștefan, Mădălin Mihai Onofrei, Christoph Tschall, Carmen-Bianca Crivii

“…Singly or as an applied technique to change the permeability of the blood–brain–barrier (BBB), FUS and TPS have demonstrated the benefits of use in treating AD in animal and human studies. Adipose-derived stem Cells (ADSCs), gene therapy, and many other alternative methods (diet, sleep pattern, physical exercise, nanoparticle delivery) are also new potential treatments since multimodal approaches represent the modern trend in this disorder research therapies.…”
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Morphological and functional convergence of visual projection neurons from diverse neurogenic origins in Drosophila by Rana Naja El-Danaf, Katarina Kapuralin, Raghuvanshi Rajesh, Félix Simon, Nizar Drou, Filipe Pinto-Teixeira, Mehmet Neset Özel, Claude Desplan

“…We show that LCNs originate from stem cells in four distinct brain regions exhibiting different modes of neurogenesis, including the ventral and dorsal tips of the outer proliferation center, the ventral superficial inner proliferation center and the central brain. …”
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Cholangiocyte organoids for disease, cancer, and regenerative medicine by Munemasa Nagao, Akihisa Fukuda, Hirotaka Kashima, Sho Matsuyama, Kei Iimori, Shinnosuke Nakayama, Kenta Mizukoshi, Munenori Kawai, Go Yamakawa, Mayuki Omatsu, Mio Namikawa, Tomonori Masuda, Yukiko Hiramatsu, Yu Muta, Takahisa Maruno, Yuki Nakanishi, Tatsuaki Tsuruyama, Hiroshi Seno

“…With advancements in 3D culture technology, cholangiocyte organoids (COs) derived from primary tissues or induced pluripotent stem cells (iPSCs) can accurately replicate the structural and functional properties of biliary tissues. …”
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MTFAP: a comprehensive platform for predicting and analyzing master transcription factors by Jianyuan Zhou, Haojie Yu, Chunhui Lou, Min Yang, Yanshang Li, Qian Yang, Shuhan Li, Chunwang Ji, Song Li, Shuang Wang, Haotian Cao, Xuecang Li, Lian Liu

“…Abstract Master transcription factors (MTFs) activate gene expression in pluripotent embryonic stem cells (ESCs) by binding to enhancers and super-enhancers, which precisely control ESC fate. …”
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Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds by Chaoxin Wang, Shuyuan Min, Jinge Liu, Bingchuan Liu, Bo Peng, Caimei Wang, Xiaolin Ma, Peng Wen, Yufeng Zheng, Yun Tian

“…Additionally, the magnesium alloy porous structures influenced the magnesium scaffold material degradation rate and the surrounding environment, impacting the osteogenic differentiation of bone mesenchymal stem cells and bone tissue regeneration. This work offers conceptual support for optimizing pore geometry to alter the mechanical and degradable characteristics of additively manufactured porous magnesium to meet therapeutic demands.…”
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Rapid Heterotrophic Ossification with Cryopreserved Poly(ethylene glycol-) Microencapsulated BMP2-Expressing MSCs by Jennifer Mumaw, Erin T. Jordan, Corinne Sonnet, Ronke M. Olabisi, Elizabeth A. Olmsted-Davis, Alan R. Davis, John F. Peroni, Jennifer L. West, Franklin West, Yangqing Lu, Steven L. Stice

“…In this study we used mesenchymal stem cells (MSCs) due to their ease of harvest, replication potential, and immunomodulatory capabilities. …”
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Fractional-Order PI Control of First Order Plants with Guaranteed Time Specifications by F. J. Castillo-Garcia, A. San Millan-Rodriguez, V. Feliu-Batlle, L. Sanchez-Rodriguez

“…Whether or not CDCs are superior to purified populations, for example, c-kit+ cardiac stem cells, or to gene therapy approaches for cardiac regeneration remains to be evaluated.…”
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Recent Advances in Application of Male Germ Cell Transplantation in Farm Animals by Ali Honaramooz, Yanfei Yang

“…Therefore, this system represents a major development in the study of spermatogenesis and a unique functional assay to determine the developmental potential and relative abundance of spermatogonial stem cells in a given population of testis cells. The application of this method in farm animals has been the subject of an increasing number of studies, mostly because of its potential as an alternative strategy in producing transgenic livestock with higher efficiency and less time and capital requirement than the current methods. …”
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Advancing cancer therapy with custom-built alternating electric field devices by Isobel Jobson, Nguyen T. N. Vo, Edward Kujawinski, Chris Denning, Snow Stolnik, Veeren M. Chauhan, Frankie Rawson

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Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer by Lukas Klein, Mengyu Tu, Niklas Krebs, Laura Urbach, Daniela Grimm, Muhammad Umair Latif, Frederike Penz, Anna Blandau, Xueyan Wu, Rebecca Diya Samuel, Stefan Küffer, Florian Wegwitz, Nathan Chan, Kazeera Aliar, Foram Vyas, Uday Kishore, Elisabeth Hessmann, Andreas Trumpp, Elisa Espinet, Argyris Papantonis, Rama Khokha, Volker Ellenrieder, Barbara T. Grünwald, Shiv K. Singh

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Emerging Applications for Optically Enabled Intravital Microscopic Imaging in Radiobiology by Azusa Maeda, Iris Kulbatski, Ralph S. DaCosta

“…Studies have demonstrated that various components of tumors and their microenvironments, including vasculature, immune and stem cells, and stromal cells, can influence the response of solid tumors to radiation. …”
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