Oncogenic RIT1 mutations confer ferroptosis vulnerability in lung adenocarcinoma by Ruilan Ma, Dian Yang, Peng Wang, Ziyi Zhang, Xuehong Zhang, Jialiang Song, Han Liu, Shuyan Liu, Yingqiu Zhang, Lijuan Zou

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Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes by Rebecca Craig-Schapiro, Ge Li, Kevin Chen, Jesus M. Gomez-Salinero, Ryan Nachman, Aleksandra Kopacz, Ryan Schreiner, Xiaojuan Chen, Qiao Zhou, Shahin Rafii, David Redmond

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Wnt/GSK‐3β mediates posttranslational modifications of FLYWCH1 to regulate intestinal epithelial function and tumorigenesis in the colon by Sheema Almozyan, Roya Babaei‐Jadidi, Abrar Aljohani, Sepideh Youssefi, William Dalleywater, Prerna Kadam, Bradley Spencer‐Dene, Emad Rakha, Mohammad Ilyas, Abdolrahman Shams Nateri

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DDX1 is required for non-spliceosomal splicing of tRNAs but not of XBP1 mRNA by Teruhiko Suzuki, Satoko Takagi, Junta Funada, Yuka Egawa, Mana Yamakawa, Takahiko Hara

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Correction: Engineering extracellular vesicles for ROS scavenging and tissue regeneration by Ahmed Abdal Dayem, Ellie Yan, Minjae Do, Yoojung Kim, Yeongseo Lee, Ssang-Goo Cho, Deok-Ho Kim

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Emerging targets of α-synuclein spreading in α-synucleinopathies: a review of mechanistic pathways and interventions by Grace Kuo, Ramhari Kumbhar, William Blair, Valina L. Dawson, Ted M. Dawson, Xiaobo Mao

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Engineering extracellular vesicles for ROS scavenging and tissue regeneration by Ahmed Abdal Dayem, Ellie Yan, Minjae Do, Yoojung Kim, Yeongseo Lee, Ssang-Goo Cho, Deok-Ho Kim

“…Abstract Stem cell therapy holds promise for tissue regeneration, yet significant challenges persist. …”
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Novel Circulating Tumour Cell-Related Risk Model Indicates Prognosis and Immune Infiltration in Lung Adenocarcinoma by Lu Liang, Yueying Liu, Shiyao Jiang, Jingjing Huang, Hua He, Li Shen, Li Cong, Yiqun Jiang

“…Circulating tumour cells (CTCs) are precursors of distant metastasis, which are considered to adopt the characteristics of cancer stem cells (CSCs). Therefore, analysing the risk factors of LUAD from the perspective of CTCs may provide novel insights into the metastatic mechanisms and may help to develop diagnostic and therapeutic strategies. …”
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Advancements and Challenges in Immune Protection Strategies for Islet Transplantation by Xue Wang, Ziyuan Zeng, Dayan Li, Kai Wang, Wei Zhang, Yang Yu, Xi Wang

“…To address these challenges, innovations such as encapsulation devices, universal stem cells, and immunomodulatory strategies are being developed to mitigate immune rejection and prolong the function of the transplant. …”
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H3K9 post-translational modifications regulate epiblast/primitive endoderm specification in rabbit blastocysts by Wilhelm Bouchereau, Hong-Thu Pham, Worawalan Samruan, Van-Hong Vu, Thierry Joly, Marielle Afanassieff, Pierre Savatier, Rangsun Parnpai, Nathalie Beaujean

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Improvement in XIa Selectivity of Snake Venom Peptide Analogue BF9-N17K Using P2′ Amino Acid Replacements by Li Ding, Zhiping Zhai, Tianxiang Qin, Yuexi Lin, Zhicheng Shuang, Fang Sun, Chenhu Qin, Hongyi Luo, Wen Zhu, Xiangdong Ye, Zongyun Chen, Xudong Luo

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Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism by Ling Xiao, Dario F. De Jesus, Cheng-Wei Ju, Jiang-Bo Wei, Jiang Hu, Ava DiStefano-Forti, Valeria Salerno Gonzales, Tadataka Tsuji, Siying Wei, Matthias Blüher, Yu-Hua Tseng, Chuan He, Rohit N. Kulkarni

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Immunomodulatory effects of mononuclear 5,6-epoxy-5,6-dihydro-1,10-phenanthroline platinum(II) complex by Stanisavljević Isidora, Živković Marija, Rajković Snežana, Obradović Milica, Jurišević Milena, Pavlović Slađana, Simović-Marković Bojana, Gajović Nevena, Ćorović Irfan, Jocić Miodrag, Kostić Andrija, Jovanović Ivan

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Advancing ex vivo functional whole-organ prostate gland model for regeneration and drug screening by Karthikeyan Subbiahanadar Chelladurai, Jackson Durairaj Selvan Christyraj, Kamarajan Rajagopalan, Johnson Retnaraj Samuel Selvan Christyraj

“…However, significant overexpression of H3 and H2AX on the 10th and 50th days suggests stem cell proliferation and differentiation. Alkaline phosphatase expression analysis confirmed that the stem cell niche is localized to the anterior region. …”
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Angiogenesis and Its Therapeutic Opportunities by So Young Yoo, Sang Mo Kwon

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miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma by Enrico Pozzo, Laura Yedigaryan, Nefele Giarratana, Chao-chi Wang, Gabriel Miró Garrido, Ewoud Degreef, Vittoria Marini, Gianmarco Rinaldi, Bernard K. van der Veer, Gabriele Sassi, Guy Eelen, Mélanie Planque, Alessandro Fanzani, Kian Peng Koh, Peter Carmeliet, Jason T. Yustein, Sarah-Maria Fendt, Anne Uyttebroeck, Maurilio Sampaolesi

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Integrated microfluidics-based construction of anti-BTN2A2 gel droplet cell preparations for non-invasive tumor-infiltrating lymphocyte therapy by Yishen Tian, Jingxuan Li, Na Yang, Yang Zhao, Jiancao Zuo, Hang Xiong, Yiwen Pan, Li Xiao, Min Su, Feng Han, Zhixu He, Rong Hu

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Endothelial-secreted Endocan activates PDGFRA and regulates vascularity and spatial phenotype in glioblastoma by Soniya Bastola, Marat S. Pavlyukov, Neel Sharma, Yasmin Ghochani, Mayu A. Nakano, Sree Deepthi Muthukrishnan, Sang Yul Yu, Min Soo Kim, Alireza Sohrabi, Natalia P. Biscola, Daisuke Yamashita, Ksenia S. Anufrieva, Tatyana F. Kovalenko, Grace Jung, Tomas Ganz, Beatrice O’Brien, Riki Kawaguchi, Yue Qin, Stephanie K. Seidlits, Alma L. Burlingame, Juan A. Oses-Prieto, Leif A. Havton, Steven A. Goldman, Anita B. Hjelmeland, Ichiro Nakano, Harley I. Kornblum

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An EED/PRC2‐H19 Loop Regulates Cerebellar Development by Pei‐Pei Liu, Xiao Han, Xiao Li, Shang‐Kun Dai, Ya‐Jie Xu, Lin‐Fei Jiao, Hong‐Zhen Du, Li‐Hua Zhao, Rong‐Feng Li, Zhao‐Qian Teng, Yun‐Gui Yang, Chang‐Mei Liu

“…Here, we show that EED deletion from neural stem cells (NSCs) or cerebellar granule cell progenitors (GCPs) leads to reduced GCPs proliferation, cell death, cerebellar hypoplasia, and motor deficits in mice. …”
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Effects of different microfracture drilling parameters on bone quality: a finite element analysis by Jiayi Luo, Jiayi Luo, Zihao Zou, Qiang Zou, Qiang Zou, Siwei Luo, Jialin He, Chuan Ye, Chuan Ye

“…BackgroundMicrofracture drilling is a surgical technique that involves creating multiple perforations in areas of cartilage defects to recruit stem cells from the bone marrow, thereby promoting cartilage regeneration in the knee joint. …”
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