Enhancing in Vitro anti-metastatic efficacy and deep penetration into tumor spheroid of docetaxel-loaded liposomes via size optimization for prostate cancer treatment by Saksorn Klibaim, Nutthanit Thumrongsiri, Natsorn Watcharadulyarat, Walailuk Chonniyom, Prattana Tanyapanyachon, Paweena Dana, Nattika Saengkrit

Subjects: Get full text

Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

Subjects: Get full text

Signal Factors Secreted by 2D and Spheroid Mesenchymal Stem Cells and by Cocultures of Mesenchymal Stem Cells Derived Microvesicles and Retinal Photoreceptor Neurons by Lili Xie, Mao Mao, Liang Zhou, Lusi Zhang, Bing Jiang

“…We aim to identify levels of signal factors secreted by MSCs cultured in 2D monolayers (2D-MSCs), spheroids (spheroids MSCs), and cocultures of microvesicles (MVs) derived from 2D-MSCs or spheroid MSCs and retinal photoreceptor neurons. …”
Get full text

Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic target by Cèlia Dobaño-López, Juan García Valero, Ferran Araujo-Ayala, Ferran Nadeu, Fabien Gava, Carla Faria, Marine Norlund, Renaud Morin, Pascale Bernes-Lasserre, Fabian Arenas, Marta Grau, Cristina López, Irene López-Oreja, Neus Serrat, Ares Martínez-Farran, Lluís Hernández, Heribert Playa-Albinyana, Rubén Giménez, Silvia Beà, Elías Campo, Jean-Michel Lagarde, Armando López-Guillermo, Laura Magnano, Dolors Colomer, Christine Bezombes, Patricia Pérez-Galán

“…Here we present the first FL-Patient Derived Lymphoma Spheroid (FL-PDLS), including fundamental immune actors and features of TME in FL lymph nodes (LNs). …”
Get full text

Inhibition of Endothelial Cell Tube Formation by Anti-Vascular Endothelial Growth Factor/Anti-Angiopoietin-2 RNA Nanoparticles by Cheng Zhong, Zhanquan Shi, Chia-Yang Liu, Daniel W. Binzel, Kai Jin, Xin Li, Peixuan Guo, S. Kevin Li

Subjects: Get full text

Highly Stable Antitumor Silver-Lipid Nanoparticles Optimized for Targeted Therapy by Darwish A, Sándor N, Szenti I, Marosvölgyi T, Juhász K, Rónavári A, Kachal E, Kutus B, Kónya Z, Balogi Z

Subjects: Get full text

Method for determining of cytotoxicity based on the release of fluorescent proteins by Dmitry Lifanov, Dulamsuren Zorigt, Evgenya Shabalina, Abdullah Khalil, Konstantin Gorbunov, Elena Petersen

Subjects: Get full text

Development and characterization of a double-crested cormorant hepatic cell line, DCH22, for chemical screening by Tasnia Sharin, Doug Crump, Jason M. O’Brien

Subjects: Get full text

Mechanism of melanoma suppression by Prosopis juliflora derived alkaloids: Apoptosis induction and signaling pathway inhibition by Jasoda Choudhari, Snehal K. Nimal, Shridhar Chougule, Trupti Shinde, N.R. Dhatrak, Gopal C. Kundu, Rajesh N. Gacche

Subjects: Get full text

Protocol to develop A 3D tumor model for drug testing applications by Prasiddha Guragain, Sunil Singh, Hossein Tavana

Subjects: Get full text

Pharmacological Vitamin C-induced high H2O2 generation mediates apoptotic cell death by caspase 3/7 activation in breast cancer tumor spheroids by Ali Mussa, Mahasin Hamid, Khalid Hajissa, Ahmad Hafiz Murtadha, Mohammad A. I. Al-Hatamleh, Noor Fatmawati Mokhtar, Vuk Uskoković, Magdalena Plebanski, Rohimah Mohamud, Rosline Hassan

Subjects: Get full text

Loss of phosphatase and tensin homolog (PTEN) increases Lysyl oxidase-like 2 (LOXL2) expression enhancing the growth of fallopian tube epithelial cells as three-dimensional spheroids by Angela Russo, Junlone Moy, Manead Khin, Timothy R. Dorsey, Alfredo Lopez Carrero, Joanna E. Burdette

“…We monitored the changes in tumorigenic properties, such as migration, invasion, and growth of three-dimensional (3D) spheroids, to assess whether the loss of LOXL2 resulted in any changes. …”
Get full text

Elastodynamic singular points and their applications by A. D. Alawneh, R. P. Kanwal

Subjects: Get full text

Unveiling the Anti-Angiogenic Potential of Small-Molecule (Kinase) Inhibitors for Application in Rheumatoid Arthritis by Fatemeh Khodadust, Eva M. L. Philippon, Maarten M. Steinz, Jan Piet van Hamburg, Johan van Meerloo, Judy R. van Beijnum, Gerrit Jansen, Sander W. Tas, Conny J. van der Laken

Subjects: Get full text

MUC2 expression modulates immune infiltration in colorectal cancer by Christophe M. Raynaud, Ayesha Jabeen, Eiman I. Ahmed, Eiman I. Ahmed, Satanay Hubrack, Apryl Sanchez, Shimaa Sherif, Ahmad A. Al-Shaibi, Bernice Lo, Bernice Lo, Jessica Roelands, Davide Bedognetti, Davide Bedognetti, Wouter Hendrickx, Wouter Hendrickx

Subjects: Get full text

Modelling hepatocellular carcinoma microenvironment phenotype to evaluate drug efficacy by Sara Cherradi, Salomé Roux, Marie Dupuy, Séverine Tabone-Eglinger, Edouard Tuaillon, Marianne Ziol, Eric Assenat, Hong Tuan Duong

Subjects: “…Patient-centric spheroid model…”
Get full text

PSWF signal based continuous phase modulation and its spectrum performance analysis by Dawei YANG, Chuanhui LIU, Jiafang KANG

Subjects: “…prolate spheroidal wave functions…”
Get full text

Hot deformation physical mechanisms and a unified constitutive model of a solid solution Ti55511 alloy deformed in the two-phase region by Huijie Zhang, Y.C. Lin, Gang Su, Yongfu Xie, Wei Qiu, Ningfu Zeng, Song Zhang, Guicheng Wu

Subjects: Get full text

Tilia species (linden) exert anti-cancer effects on MIA PaCa-2 cells through the modulation of oxidative stress and inflammation by Gamze Yüksel, Yağmur Özhan, Dilara Güreşçi, Etil Güzelmeriç, Nisa Beril Şen, İpek Bedir, Onur Senol, Gizem Emre, Dilek Telci, Vilma Petrikaitė, Hande Sipahi

Subjects: Get full text

PEGDA-based HistoBrick for increasing throughput of cryosectioning and immunohistochemistry in organoid and small tissue studies by Emilie Vuille-dit-Bille, Larissa Utz, Fiona E. Müllner, Valeria J. Arteaga-Moreta, Yanyan Hou, Stefan E. Spirig, Diane Ledroit-Paic, Sarah Heub, Jonas Goldowsky, Gilles Weder, Magdalena Renner

Subjects: Get full text