The different response of PM2.5 stimulated nasal epithelial spheroids in control, asthma and COPD groups by Paulina Misiukiewicz-Stępień, Elwira Zajusz-Zubek, Katarzyna Górska, Rafał Krenke, Magdalena Paplińska-Goryca

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Optimizing Imaging of Three-Dimensional Multicellular Tumor Spheroids with Fluorescent Reporter Proteins Using Confocal Microscopy by Lucia le Roux, Andrei Volgin, David Maxwell, Katashi Ishihara, Juri Gelovani, Dawid Schellingerhout

“…Tumor spheroids more faithfully mimic tumor biology than monolayer cultures and require three-dimensional microscopy. …”
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Effects of linsitinib on M22 and IGF:1-treated 3D spheroids of human orbital fibroblasts by Fumihito Hikage, Megumi Suzuki, Tatsuya Sato, Araya Umetsu, Toshifumi Ogawa, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro, Megumi Watanabe

“…As for physical properties of 3D GHOFs spheroids, stiffness but not size was significantly increased by IGF1 and/or M22. …”
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Synergistic Approach of High-Precision 3D Printing and Low Cell Adhesion for Enhanced Self-Assembled Spheroid Formation by Chunxiang Lu, Aoxiang Jin, Chuang Gao, Hao Qiao, Huazhen Liu, Yi Zhang, Wenbin Sun, Shih-Mo Yang, Yuanyuan Liu

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A multi-stage weakly supervised design for spheroid segmentation to explore mesenchymal stem cell differentiation dynamics by Arash Shahbazpoor Shahbazi, Farzin Irandoost, Reza Mahdavian, Seyedehsamaneh Shojaeilangari, Abdollah Allahvardi, Hossein Naderi-Manesh

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Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis by Takenori Suga, Michihiko Usui, Satoru Onizuka, Kotaro Sano, Tsuyoshi Sato, Kohji Nakazawa, Wataru Ariyoshi, Tatsuji Nishihara, Keisuke Nakashima

“…A spheroid is known as a three-dimensional culture model, which better simulates the physiological conditions of stem cells. …”
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A Probe-Compensated Helicoidal NF-FF Transformation for Aperture Antennas Using a Prolate Spheroidal Expansion by Amedeo Capozzoli, Claudio Curcio, Giuseppe D'Elia, Flaminio Ferrara, Claudio Gennarelli, Rocco Guerriero, Angelo Liseno

“…Such a technique takes the advantage of the NF data acquisition made according to a very efficient sampling strategy along a helix and exploits a proper aperture field expansion based on the use of the prolate spheroidal wave functions (PSWFs), accounting for the a priori information on shape and size of the antenna under test. …”
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A Chemically Defined Serum-Free Culture System for Spontaneous Human Mesenchymal Stem Cell Spheroid Formation by Yajun Zhao, E. Xiao, Wanqi Lv, Xian Dong, Linhai He, Yixiang Wang, Yi Zhang

“…Previous studies demonstrated that spheroid formation of MSCs exhibited improved stemness maintenance and therapeutic potential compared with monolayer culture. …”
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Imaging Herpes Simplex Virus Type 1 Amplicon Vector–Mediated Gene Expression in Human Glioma Spheroids by Christine Kaestle, Alexandra Winkeler, Raphaela Richter, Heinrich Sauer, Jürgen Hescheler, Cornel Fraefel, Maria Wartenberg, Andreas H. Jacobs

“…After infection or microscopy-guided vector injection of glioma spheroids at various spheroid sizes, injection pressures and injection times, the extent of HSV-1 vector–mediated gene expression was investigated via laser scanning microscopy. …”
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High-quality nodule analysis in spheroidal graphite cast iron using X-ray micro-computed tomography by Juan Toledo, Felipe Diaz, Matías Peralta, Diego Fernandino

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The development of production technology of wire rod from chromium-nickel-molibdenum steel grades with subsequent annealing spheroidization by S. V. Аudzeyey

“…The peculiarity of the rod of chromium-nickel-molybdenum steel grades, used in the production of fasteners and automotive components by cold forming, are the high requirements for the quality of the surface, microstructure and physical and mechanical properties.In the process of development of production technology were developed and implemented measures to minimize the identified design features of heat treatment furnaces, and developed methods for obtaining the most optimal primary hot-rolled metal microstructure for further spheroidizing annealingIn industrial conditions OJSC «BSW – Management Company of Holding «BMC» was mastered the most optimal regimes of heat treatment of wire rod from chromium-nickel-molybdenum steel grades, which required the consumer a full range of physical and mechanical properties of wire rod from steel grades 38ХНГМ, 40XH2MA and 41Х1 used further in the manufacture of fasteners and automotive components by cold forging.…”
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Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids by Julie Bejoy, Xuegang Yuan, Liqing Song, Thien Hua, Richard Jeske, Sébastien Sart, Qing-Xiang Amy Sang, Yan Li

“…Brain spheroids or organoids derived from human pluripotent stem cells (hiPSCs) are still not capable of completely recapitulating in vivo human brain tissue, and one of the limitations is lack of microglia. …”
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High-quality nodule analysis in spheroidal graphite cast iron using X-ray micro-computed tomography by J. C. Toledo, F. V. D�az, M.E. Peralta, D. O. Fernandino

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Multicellular Tumor Spheroids as an in Vivo–Like Tumor Model for Three-Dimensional Imaging of Chemotherapeutic and Nano Material Cellular Penetration by Hui-li Ma, Qiao Jiang, Siyuan Han, Yan Wu, Jin Cui Tomshine, Dongliang Wang, Yaling Gan, Guozhang Zou, Xing-Jie Liang

“…We generated HeLa cell–derived spheroids using the liquid overlay method. To properly characterize HeLa spheroids, scanning electron microscopy, transmission electron microscopy, and multiphoton microscopy were used to obtain high-resolution 3D images of HeLa spheroids. …”
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Preliminary study of utilizing a patient derived tumor spheroid model to augment precision therapy in metastatic brain tumors by Chun-Jen Chang, Kai-Wen Kan, Yu-Yin Shih, Yu-Han Nan, Yu-Chung Juan, Chih-Hsiu Tu, Chen-Ting Yang, Wei-Lin Hsu, Der-Yang Cho, Ming-You Shie, Yi-Wen Chen, Chun-Chung Chen

Subjects: “…Patient-derived tumor spheroids…”
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Diffusion Smart-seq3 of breast cancer spheroids to explore spatial tumor biology and test evolutionary principles of tumor heterogeneity by Antony Cougnoux, Loay Mahmoud, Per A. Johnsson, Alper Eroglu, Louise Gsell, Jakob Rosenbauer, Rickard Sandberg, Jean Hausser

“…Abstract Combining 3D cultures such as tumor spheroids and organoids with spatial omics holds great potential for tissue biology and cancer research. …”
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Renewable Human Cell Model for Type 1 Diabetes Research: EndoC-βH5/HUVEC Coculture Spheroids by James M. Porter, Michael Yitayew, Maryam Tabrizian

“…This pilot study indicated that stimulated insulin release from 0 to 20 mM glucose increased from ~8-fold for monoculture and 1 : 1 coculture spheroids to over 20-fold for 1 : 3 EndoC-βH5/HUVEC spheroids. …”
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APPLICATION OF SPHEROIDIZING «CHIPS»-MASTER ALLOY ON COPPER BASE CONTAINING NANOSCALE PARTICLES OF YTTRIUM OXIDE FOR HIGH-STRENGTH CAST IRON by A. S. Kalinichenko, A. G. Slutsky, V. A. Sheinert, S. A. Lenkevich, A. N. Bely

Subjects: “…inoculants based on copper and magnesium, nanosized powder of yttrium oxide, high-speed shock impact, chemical and phase composition of «chips»-inoculants, ductile iron, melting, spheroidizing treatment, microstructure, mechanical and technological properties…”
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Deep Learning for Predicting Spheroid Viability: Novel Convolutional Neural Network Model for Automating Quality Control for Three-Dimensional Bioprinting by Zyva A. Sheikh, Oliver Clarke, Amatullah Mir, Narutoshi Hibino

Subjects: “…spheroid…”
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Effects of Insulin-like Growth Factor 1 on the Maintenance of Cell Viability and Osteogenic Differentiation of Gingiva-Derived Mesenchymal Stem Cell Spheroids by Somyeong Hwa, Hyun-Jin Lee, Youngkyung Ko, Jun-Beom Park

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