Dedifferentiated Leiomyosarcoma of the Uterus with Heterologous Elements: A Potential Diagnostic Pitfall by Kojo R. Rawish, Oluwole Fadare

“…The tumor recurred six months after its resection as an undifferentiated sarcoma that was negative for smooth muscle markers, but which remained positive for ER and PR. …”
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Cellular Imaging of Inflammation in Atherosclerosis Using Magnetofluorescent Nanomaterials by Farouc A. Jaffer, Matthias Nahrendorf, David Sosnovik, Kimberly A. Kelly, Elena Aikawa, Ralph Weissleder

“…On fluorescence microscopy, MFNPs were found in cellular-rich areas of atheroma and colocalized with immunofluorescent macrophages over endothelial cells and smooth muscle cells ( p < .001). Conclusions: Here we show that (1) the in vitro and in vivo cellular distribution of atherosclerosis-targeted MFNPs can be quantified by using fluorescence imaging methods; (2) in atherosclerosis, dextranated MFNPs preferentially target macrophages; and (3) MFNP deposition in murine atheroma can be noninvasively detected by in vivo MRI. …”
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Prostatic Leiomyoma: A Case Report by Soufiane Mellas, Ahmed Amine Bouchikhi, Mohammed-Fadl Tazi, Abdelhak Khallouk, Jalal-Eddin Elammari, Mohammed-Jamal El Fassi, Moulay Hassan Farih

“…The histopathological examination revealed a benign smooth muscle tumor with absence of glandular hyperplasia; the result was confirmed by immunohistochemistry. …”
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Prostanoid Receptors in the Human Vascular Wall by Xavier Norel

“…The mechanisms involved in vascular homeostasis and disease are mostly dependent on the interactions between blood, vascular smooth muscle, and endothelial cells. There is an accumulation of evidence for the involvement of prostanoids, the arachidonic acid metabolites derived from the cyclooxygenase enzymatic pathway, in physiological and/or pathophysiological conditions. …”
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The role of tribbles homolog 2 in cell proliferation by Wenkang Zhang, Mingkang Li, Minhao Zhang, Gaoliang Yan, Chengchun Tang

“…TRIB2 is not only involved in the physiological proliferation of cells (granulosa cells, myoblasts, naive T cells, and thymocytes) during normal development but also in the pathological proliferation of vascular smooth muscle cells and a variety of cancer cells (lung cancer cells, liver cancer cells, leukemia cells, pancreatic cancer cells, gastric cancer cells, prostate cancer cells, thyroid cancer cells, cervical cancer cells, melanoma cells, colorectal cancer cells, ovarian cancer cells and osteosarcoma cells) under disease conditions. …”
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Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the Literature by Jacob Albersheim-Carter, Molly Klein, Paari Murugan, Christopher J. Weight

“…Renal angiomyolipomas are neoplasms of mesenchymal origin with varying proportions of vasculature, smooth muscle spindle cells, and adipocytes, making management of such neoplasms a challenging endeavor. …”
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Enteric Duplication Cyst Containing Squamous and Respiratory Epithelium: An Interesting Case of a Typically Pediatric Entity Presenting in an Adult Patient by Jessica Leigh Baumann, Charmi Patel

“…They are characterized by the presence of an outer layer of smooth muscle and an inner lining of mucosa that may resemble any portion of the digestive tract. …”
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Therapeutic Implications of PPARγ in Cardiovascular Diseases by Hiroshi Hasegawa, Hiroyuki Takano, Issei Komuro

“…In addition, activation of PPARγ is implicated in the regulation of endothelial function, proliferation and migration of vascular smooth muscle cells, and activation of macrophages. Many studies suggest that PPARγ ligands not only ameliorate insulin sensitivity, but also have pleiotropic effects on the pathophysiology of atherosclerosis, cardiac hypertrophy, ischemic heart, and myocarditis.…”
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Malignant Perivascular Epithelioid Cell Tumor of the Esophagus by Matteo Fassan, Mauro Cassaro, Massimo Vecchiato, Roberto Clemente, Gianmaria Pennelli, Stefano Merigliano, Giuseppe Altavilla

“…Malignant perivascular epithelioid cell tumor (PEComa) is a rare tumor composed of hybrid tumor cells characterized by immunoreactivity for both melanocytic and smooth muscle markers. This paper describes the uncommon esophageal location of an 8 cm PEComa in a 75-year-old Caucasian man who was presented with ingravescent dysphagia. …”
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Promotion of nitric oxide production: mechanisms, strategies, and possibilities by Marcos Gonzalez, Sarah Clayton, Eric Wauson, Daniel Christian, Quang-Kim Tran

“…Endothelium-derived NO activates soluble guanylate cyclase (sGC) in vascular smooth muscle cells (VSMCs), elevating cyclic GMP (cGMP), causing vasodilation. …”
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New Aspects in the Differential Diagnosis and Therapy of Bladder Pain Syndrome/Interstitial Cystitis by Jochen Neuhaus, Thilo Schwalenberg, Lars-Christian Horn, Henry Alexander, Jens-Uwe Stolzenburg

“…Analysis of molecular alterations of receptor expression in detrusor smooth muscle cells and urothelial integrity is necessary to develop patient-tailored therapeutical concepts. …”
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Airway Remodelling in Asthma: From Benchside to Clinical Practice by Céline Bergeron, Meri K Tulic, Qutayba Hamid

“…In asthma, airway structural changes include subepithelial fibrosis, increased smooth muscle mass, gland enlargement, neovascularization and epithelial alterations. …”
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A Spontaneous Isolated Superior Mesenteric Artery Dissection Associated with Cocaine Abuse: A Pathomechanistic Association by Rayan S. El-Zein, Jeffrey Sobecki, Roy Greenberg, Michael Keleher, Robert A. Palma

“…Cocaine and SISMAD share similar pathophysiologic mechanisms pertaining to vascular smooth muscle cell apoptosis and increased shear stress at fixed vascular positions. …”
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Exploring the Mechanism of Microarteriogenesis in Porous Silk Fibroin Film by Lun Bai, Guangqian Wang, Xiaoyan Tan, Jianmei Xu

“…After the porous silk fibroin materials are implanted into the back hypodermal tissue of SD rats, the arteriole development and the morphogenesis of smooth muscle cell are histologically monitored and the micro-arteriogenesis is quantitatively analyzed. …”
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Glomus Tumor in the Left Submandibular Region: A Rare Case Report and Literature Review by Huan Liu, Chengyao Zhu

“…Immunohistochemical (IHC) staining further confirmed the tumor's smooth muscle and mesenchymal origins, with positive for Vimentin, SMA, Syn, Actin, Desmin, and CD34. …”
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Identification of disulfidptosis-related subtypes in gastric cancer and GAMT is a key gene during disulfidptosis by Wenxue Wu, Guoqiang Tao, Zhiqing Chen, Qi Zhou

“…Mesenchymal cells, especially myCAF, endothelial cells, and smooth muscle cells, have strong disulfidptosis scores. …”
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Study of Histomorphological Patterns of Uterine Leiomyomas: An Observational Study by Archana Tiwari, Pratima Sapkota

“… Introduction: Uterine leiomyoma, also known as a fibroid, is a benign mesenchymal tumor derived from the smooth muscle of the uterus. It is the most common tumor in women with an estimated incidence of 20%-40% in women during their reproductive years. …”
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Clinicopathological analysis of sclerosing angiomatoid nodular transformation in the spleen by Shufei Wei, Yongliang Han, Yingyong Hou, Liangliang Wang

“…The hemangiomatous nodules were positive for CD31 and CD34, while the vascular wall smooth muscle cells and fibrocytes around the nodules were positive for SMA. …”
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Primary sclerosing cholangitis by Marina G Silveira, Keith D Lindor

“…A cholestatic picture of liver biochemistries with elevations in serum alkaline phosphatase, nonspecific autoantibodies such as perinuclear antineutrophilic antibody, antinuclear antibodies and smooth muscle antibodies, and diffuse multifocal biliary strictures, resulting in a ‘beaded’ appearance on radiographic studies, are the hallmarks of the disease. …”
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Roles of Cells from the Arterial Vessel Wall in Atherosclerosis by Di Wang, Zhiyan Wang, Lili Zhang, Yi Wang

“…The migration and proliferation of smooth muscle cells also play a pivotal role in the progression of atherosclerosis. …”
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