LIVER DISEASE & SICKLE CELL DISEASE: AUTOIMMUNE HEPATITIS MORE THAN A COINCIDENCE; A SYSTEMATIC LITERATURE REVIEW. by Kelvin Lynch, Andrea Mega, Andrea Piccin, Massimo Daves, Helen Fogarty

“…Autoimmune hepatitis (AIH) is a rare disease that appears to occur more commonly in the sickle cell disease (SCD) population than in the general population. …”
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Multimodal Imaging in Retinal Vascular Occlusions following Trauma – A Case of Sickle Cell Disease with Negative Sickling Test by Ekta Singh Sahu, Mani Sachdeva, Alok Sen, Samendra Karkhur

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Acute Soft Head Syndrome as the Initial Presentation of Sickle Cell Disease in an Adolescent in Rural Western Uganda: Case Report by Abukar Ali Ahmed, Dalton Kambale Munyambalu, Awil Abdulkadir Abdi, Elias Joseph Xwatsal, Hanan Asad Hassan, Ibrahim Ahmed Nur, Abdikani Ali Hassan, Venance Emmanuel Mswelo

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Associations between disease severity, depression, health-related quality of life, and physical activity in adults with sickle cell disease by Adekola B. Ademoyegun, Mutiu A. Adeyemo, Babatunde Y. Adewuyi, Adebukola G. Ibitoye, Olalekan I. Akerele, Taofeek O. Awotidebe, Chidozie E. Mbada

“…Abstract Background Individuals with sickle cell disease (SCD) are faced with a plethora of challenges that affect their quality of life, mood, and physical and social participation. …”
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Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells by Philip M. Keegan, Sindhuja Surapaneni, Manu O. Platt

“…Sickle cell disease is a genetic disease that increases systemic inflammation as well as the risk of pediatric strokes, but links between sickle-induced inflammation and arterial remodeling are not clear. …”
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A Child as a Donor for Hematopoietic Stem Cell Transplantation: Bioethical Justification—A Case Study on Sickle Cell Disease by Andrea Z. Pereira, Ricardo Hellman, Nelson Hamerschlak, Andrea Kondo, Polianna Mara Rodrigues de Souza, Wilson Leite Pedreira, Luiz Fernando Alves Lima Mantovani, Eduardo Juan Troster, Henrique Grunspun, Marco Aurélio Scarpinella Bueno

“…Hematopoietic stem cell transplantation (HSCT) is an important treatment option for children with severe and refractory sickle cell disease (SCD) with debilitating clinical complications. …”
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Effectiveness of implementation of sickle cell disease referral guidelines and other measures in paediatric department at a tertiary hospital in Saudi Arabia by Muhammad Matloob Alam, Abdulrhman Alathaibi, Hamdan Alghamdi, Jean Barrientos De Asis, Reynan Bautista, Mansour Aladwani, Mustafa Mohamed Selim

“…Background Sickle cell disease (SCD) is an autosomal recessive genetic blood disorder. …”
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Awareness, attitude, and acceptance of newborn screening for sickle cell disease among health workers and caregivers at primary healthcare centers in Gwagwalada Area Council, Federal Capital Territory, Abuja, Nigeria by Isa Hezekiah A, Chisomaga Ifeanyi Oparaugo, Grace Doyin Ajetomobi, Ayomide Esther Fasina, Reuben Ikechukwu Chianumba, Obiageli Eunice Nnodu, Obiageli Eunice Nnodu

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Association Between Vaso-Occlusive Crises and Opioid Prescriptions Among Patients with Sickle Cell Disease: A Retrospective Claims-Based Study by Hyeun Ah Kang, Jamie C. Barner, Kristin M. Richards, Menaka Bhor, Jincy Paulose, Abdullah Kutlar

“…**Background/Objectives:** Among sickle cell disease (SCD) patients, vaso-occlusive crises (VOCs) are recurrent and unpredictable attacks of acute pain. …”
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The added role of Doppler ultrasound evaluation of sickle cell disease vasculopathy as a state of arterial stiffness and decreased nitric oxide bioavailability by Marwa Mohammed Mohammed Onsy, Sonia Ali El-Saiedi, Douaa Mohammed Mohammed Elsheshtawy, Marwa Abd-Elhady Abd-Elsamad

“…Abstract Background Sickle cell disease is an inherited hemoglobinopathy resulting in chronic hemolysis and painful vaso-occlusive crises. …”
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Elevated Circulating Angiogenic Progenitors and White Blood Cells Are Associated with Hypoxia-Inducible Angiogenic Growth Factors in Children with Sickle Cell Disease by Solomon F. Ofori-Acquah, Iris D. Buchanan, Ifeyinwa Osunkwo, Jerry Manlove-Simmons, Feyisayo Lawal, Alexander Quarshie, Arshed A. Quyyumi, Gary H. Gibbons, Beatrice E. Gee

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Identifying strokes in Nigerian children with sickle cell disease as part of clinical trials: training curriculum for healthcare professionals in low-income settings by Djamila L. Ghafuri, Halima Bello-Manga, Fenella J. Kirkham, Mariana Ciobanu, Edwin Trevathan, Edwin Trevathan, Mark Rodeghier, Michael R. DeBaun, Michael R. DeBaun, Lori C. Jordan

“…In low-resource settings, training to recognize and prevent strokes in children with SCA is vital. A sustainable Sickle Cell Disease Stroke Prevention Teams program was established, as part of clinical trials, to address the need for stroke care in northern Nigeria. …”
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Automated red cell exchange in sickle cell disease patients: Retrospective analysis of series of cases in a tertiary care hospital in Eastern India by Girijanandini Kanungo, Priyanka Nagrath, Priyanka Samal, Santosh Mishra

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Effect of empowerment-based interventions on self-efficacy and self-care capacity among patients with sickle cell disease: A randomized controlled trial by Zohour Ibrahim Rashwan, Hasan Abdali Khalil, Leena Mohamed Khonji, Gayathripriya Narayanan, Marwan Kamal Altheeb, Roseben Pradeep, Rajeswari Krishnasamy, Magda Mohamed Bayoumi

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A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study by Lauren Kelenc, Brittany Wiles, Fareha Nishat, Chitra Lalloo, Anya Nair, Craig Eling, Melanie Kirby-Allen, Ewurabena Simpson, Roona Sinha, Richard Ward, William T. Zempsky, Sara Ahola Kohut, Jennifer N. Stinson

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Dissemination of Evidence-Based Recommendations for Sickle Cell Disease to Primary Care and Emergency Department Providers in North Carolina: A Cost Benefit Analysis by Paula Tanabe, Audrey L. Blewer, Emily Bonnabeau, Hayden B. Bosworth, Denise H. Clayton, Nancy Crego, Marian F. Earls, Kern Eason, Grayson Forlines, Gary Rains, Matthew Young, Nirmish Shah

“…**Background:** Sickle cell disease (SCD) is a genetic condition affecting primarily individuals of African descent, who happen to be disproportionately impacted by poverty and who lack access to health care. …”
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Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature Review by Michael Ebiyon Ugbeye, Kehinde Adesola Alatishe, Chukwuebuka Okezie

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Pentazocine Misuse among Sickle Cell Disease Patients and The Role of Lack of Enforcement of Opioid Dispensing Regulations by Community Pharmacies: A Descriptive Observational Study by Oluomachi Charity Nnachi, Chinedu Obasi Akpa, Favour Ogonna Nwani, Oghenevwogaga Obukohwo Edenya

“…Introduction. Sickle cell disease (SCD) is a chronic disease characterized by debilitating bone pains which commonly necessitate the use of analgesic drugs including opioids and psychotropic substances such as pentazocine which are controlled medicines in Nigeria. …”
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Red Blood Cell Alloimmunization and Autoimmunization in Blood Transfusion-Dependent Sickle Cell Disease and β-Thalassemia Patients in Al-Ahsa Region, Saudi Arabia by Fahd A. Kuriri, Abdulrahman Ahmed, Fehaid Alanazi, Fahad Alhumud, Mohammed Ageeli Hakami, Osama Atiatalla Babiker Ahmed

“…It is important to determine the rate of alloimmunization and autoimmunization in Al-Ahsa Region, Saudi Arabia, where sickle cell disease (SCD) and thalassemia incidence rates are the highest in Saudi Arabia. …”
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Comprehensive Neonatal Screening for Genetic Disorders in Tribal Populations of Central India by Rakesh K. Jha, Meghali Kaple, Ranjit S. Ambad, Archana Dhok, Ashsish Anjankar

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