Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study by Narcisse Elenga, Aurélie Adeline, John Balcaen, Tania Vaz, Mélanie Calvez, Anne Terraz, Laetitia Accrombessi, Gabriel Carles

“…Sickle cell disease is a serious genetic disorder affecting 1/235 births in French Guiana. …”
Get full text

Bacteraemia Among Patients with Sickle Cell Disease in Nigeria: Association with Spleen Size and Function by adama isah ladu, Mairo Usman Kadaura, Mohammed Dauda, Abubakar Sadiq Baba, Caroline Jeffery, Abubakar Farate, Adekunle Adekile, Imelda Bates, Russell Dacombe

Subjects: Get full text

Bacteroides fragilis Acute Hematogenous Osteomyelitis in a Young Female with Sickle Cell Disease by Nada Bassam Hamieh, Hiba Abdul Hamid Abou Layla, Rola Ali Ali, Zeina Bayram, Abdul Rahman Bizri

“…Patients with sickle cell disease are at increased risk for multiple infections including osteomyelitis. …”
Get full text

Challenges Faced by Nurses in Transitioning Pediatric Sickle Cell Disease Patients to Adult Care by Gifty Enyonam Amoaku, Delali Adwoa Wuaku, Vivian Efua Senoo-Dogbey

“…Background Sickle-cell disease is a common genetic red blood cell disorder with global concern. …”
Get full text

The Neonatal Screening for Sickle Cell Disease, Thalassemia, and G6PD Deficiency in Central India by Rakesh K. Jha, Meghali Kaple, Ranjit S. Ambad, Archana Dhok, Ashsish Anjankar

Subjects: Get full text

Patent Foramen Ovale in Patients with Sickle Cell Disease and Stroke: Case Presentations and Review of the Literature by Sheila Razdan, John J. Strouse, Rakhi Naik, Sophie Lanzkron, Victor Urrutia, Jon R. Resar, Linda M. S. Resar

“…Although individuals with sickle cell disease (SCD) are at increased risk for stroke, the underlying pathophysiology is incompletely understood. …”
Get full text

Daily Changes in Pain, Mood and Physical Function in Youth Hospitalized for Sickle Cell Disease Pain by William T Zempsky, Tonya M Palermo, John M Corsi, Amy S Lewandowski, Chuan Zhou, James F Casella

“…BACKGROUND: Youth with sickle cell disease (SCD) are commonly hospitalized for treatment of painful vaso-occlusive episodes (VOE). …”
Get full text

Epidemiological profile trends and cost of pediatric sickle cell disease in Brazil from 2008 to 2022 by Luiza Telles, Paulo Henrique Moreira Melo, Luana Baptistele Dornelas, Gabriele Eckerdt Lech, Natália Zaneti Sampaio, Ayla Gerk, Madeleine Carroll, Cristina Pires Camargo

“…Objective: This study aimed to investigate the epidemiological trends of Pediatric Sickle Cell Disease (SCD) in Brazil over the period 2008–2022, with a focus on understanding the incidence, mortality rates, and associated healthcare costs. …”
Get full text

Cerebral hemodynamics and oxygen metabolism in patients with milder and severe forms of sickle cell disease and thalassemia by Liza Afzali‐Hashemi, Koen P. A. Baas, Anouk Schrantee, Erfan Nur, Chau Vu, Soyoung Choi, Silvie Suriany, John C. Wood, Aart J. Nederveen, Bart J. Biemond

“…Abstract Silent cerebral infarcts (SCIs) are present in patients with sickle cell disease (SCD) and thalassemia, but the pathophysiology of SCIs is not fully understood. …”
Get full text

Mycobacterium avium Complex Infection in a Patient with Sickle Cell Disease and Severe Iron Overload by Kamal Shemisa, Nasima Jafferjee, David Thomas, Gretta Jacobs, Howard J. Meyerson

“…An appreciable number of mycobacterial infection cases have been reported in sickle cell disease patients without immune dysfunction. …”
Get full text

Crizanlizumab and comparators for adults with sickle cell disease: a systematic review and network meta-analysis by George Joseph, Howard Thom, Jeroen Jansen, Hung-Yuan Cheng, Jason Shafrin, Lauren Zhao, Subhajit Gupta, Nirmish Shah

“…Objectives Treatment options for preventing vaso-occlusive crises (VOC) among patients with sickle cell disease (SCD) are limited, especially if hydroxyurea treatment has failed or is contraindicated. …”
Get full text

Challenges of Engaging Primary Care Providers in Specialized Telementoring Education About Sickle Cell Disease for Sickle Cell Specialists: Results from the Sickle Cell Disease Training and Mentoring Program for Primary Care Providers (STAMP) Project ECHO by Lisa M. Shook, DHPE, MA, MCHES, Bailey House, MPH, Christina Bennett Farrell, MPH, Rosalyn Stewart, MD, Sophie Lanzkron, MD, MHS, Allison A. King, MD, MPH, PhD, Taniya Varughese, MSOT, J.J. Strouse, MD, PhD, Marsha Treadwell, PhD, Julie Kanter, MD

Subjects: “…Sickle cell disease…”
Get full text

Perceptions and Practice of Early Diagnosis of Sickle Cell Disease by Parents and Physicians in a Southwestern State of Nigeria by Oladele Simeon Olatunya, Adefunke Olarinre Babatola, Ezra Olatunde Ogundare, Babatunde Ajayi Olofinbiyi, Olubunmi Adeola Lawal, Jacob Olumuyiwa Awoleke, Olusola Peter Aduloju, Alaba Olanrewaju Daramola, Eyitayo Ebenezer Emmanuel, Oyebanji Anthony Olajuyin, Akinwumi Kolawole Komolafe, Abiola Olukayode Olaleye

“…Background. Early sickle cell disease (SCD) diagnosis has shown promise in combating SCD in many countries. …”
Get full text

Benchmarking Pain Outcomes for Children with Sickle Cell Disease Hospitalized in a Tertiary Referral Pediatric Hospital by Abi Vijenthira, Jennifer Stinson, Jeremy Friedman, Lori Palozzi, Anna Taddio, Dennis Scolnik, Charles Victor, Melanie Kirby-Allen, Fiona Campbell

“…BACKGROUND: Painful vaso-occlusive crisis (VOC) is the most common reason for hospitalization in children with sickle cell disease.…”
Get full text

Attitudes toward Management of Sickle Cell Disease and Its Complications: A National Survey of Academic Family Physicians by Arch G. Mainous, Rebecca J. Tanner, Christopher A. Harle, Richard Baker, Navkiran K. Shokar, Mary M. Hulihan

“…Objective. Sickle cell disease (SCD) is a disease that requires a significant degree of medical intervention, and family physicians are one potential provider of care for patients who do not have access to specialists. …”
Get full text

Profiles of systemic lupus erythematosus patients with co-existing sickle cell disease: a coincidence or true association? by Hakeem Babatunde Olaosebikan, Etseoghena Igebu, Adebukola Khairat Orolu, Gbenga Joshua Odunlami, Ilo Azizat Bamisebi, Akin Dada, Ebele Uche, Olufemi Adelowo

Subjects: Get full text

High Healthcare Utilization in Adolescents with Sickle Cell Disease Prior to Transition to Adult Care: A Retrospective Study by Julie Kanter, Menaka Bhor, Xin Li, Frank Li, Jincy Paulose

“…**Background:** The transition from pediatric to adult care in the US is often difficult for individuals with sickle cell disease (SCD). Young adults (18 to 25 years of age) have higher acute care utilization and an increased risk of poor outcomes. …”
Get full text

Assessment of healthcare workers’ knowledge and availability of resources for sickle cell disease management in Bukavu, Democratic Republic of the Congo by Nash Mwanza Nangunia, Olivier Mukuku, Viviane Bianga Feza, Yves Mulindilwa Kyembwa, Théophile Barhwamire Kabesha, André Kabamba Mutombo, Stanislas Okitostho Wembonyama

Subjects: “…Sickle Cell Disease…”
Get full text

Base editing HbS to HbG-Makassar improves hemoglobin function supporting its use in sickle cell disease by Zachary Kostamo, Manuel A. Ortega, Chavonna Xu, Patricia R. Feliciano, Elizabeth Budak, Daisy Lam, Valerie Winton, Rebecca Jenkins, Archita Venugopal, Margaret Zhang, John Jamieson, Brent Coisman, Kennedy Goldsborough, Britney Hernandez, Celeste K. Kanne, Erica N. Evans, Jordan Zgodny, Yankai Zhang, Jawa Darazim, Ashwin Patel, Michael A. Pendergast, John Manis, Adam J. Hartigan, Giuseppe Ciaramella, Seung-Joo Lee, S. Haihua Chu, Vivien A. Sheehan

Get full text

Evaluation of Vaso-occlusive Crises in United States Sickle Cell Disease Patients: A Retrospective Claims-based Study by Nirmish Shah, Menaka Bhor, Lin Xie, Steve Arcona, Rashid Halloway, Jincy Paulose, Huseyin Yuce

“…Sickle cell disease (SCD) is a life-threatening vascular disease that burdens affected persons physically. …”
Get full text