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DRG2 as a Biomarker to Enhance the Predictive Efficacy of PD-L1 Immunohistochemistry Assays
Published 2024-12-01“…Although DRG2-depleted cells express high levels of PD-L1 and are PD-L1 IHC-positive, the PD-L1 sequestered in early endosomes does not respond to ICIs. …”
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62
REV7: a small but mighty regulator of genome maintenance and cancer development
Published 2025-01-01“…REV7 also ensures accurate cell cycle progression and prevents premature mitotic progression by sequestering an anaphase-promoting complex/cyclosome activator. …”
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63
PIN2-mediated self-organizing transient auxin flow contributes to auxin maxima at the tip of Arabidopsis cotyledons
Published 2025-02-01“…Once IAA levels at the cotyledon tip reaches a maximum, it activates pavement cell interdigitation as well as the accumulation of the IBA transporter TOB1 in MCs, which sequesters IBA to the vacuole and reduces IBA availability and IAA levels. …”
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64
Improvement in Carbonation Resistance of Portland Cement Mortar Incorporating γ-Dicalcium Silicate
Published 2019-01-01“…In this study, γ-dicalcium silicate (γ-C2S) was incorporated into ordinary Portland cement (OPC) to sequester CO2 to enhance the carbonation resistance of cement-based composite materials. γ-C2S can react with CO2 rapidly to form vaterite and high dense SiO2 gel which could block the pores off and then inhibit further diffusion of CO2 into the system. …”
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65
Lead Speciation and Bioavailability in Apatite-Amended Sediments
Published 2011-01-01“…The study indicates limited effectiveness of apatite in sequestering Pb if present as PbS under reducing conditions, but sequestration of porewater Pb and stabilization of near-surface sediment may be a feasible and alternative approach to decreasing potential toxicity of Pb.…”
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66
Susy at the FPF
Published 2025-02-01“…We show that using next generation LHC experiments currently envisioned for the Forward Physics Facility (FPF) we could search for signals of neutrino-modulino oscillations to probe models with string scale in the grand unification region and SUSY breaking driven by sequestered gravity in gauge mediation. This is possible because of the unprecedented flux of neutrinos to be produced as secondary products in LHC collisions during the high-luminosity era and the capability of FPF experiments to detect and identify their flavors.…”
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67
MAP1B Interaction with the FW Domain of the Autophagic Receptor Nbr1 Facilitates Its Association to the Microtubule Network
Published 2012-01-01“…Selective autophagy is a process whereby specific targeted cargo proteins, aggregates, or organelles are sequestered into double-membrane-bound phagophores before fusion with the lysosome for protein degradation. …”
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68
Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO
Published 2014-01-01“…The difference in sensitivity to LMP appears to be in cholesterol recycling since increasing cholesterol in AM by treatment with U18666A decreased silica-induced NLRP3 inflammasome activation, and cells lacking MARCO were less able to sequester cholesterol following silica treatment. Taken together, these results demonstrate that MARCO contributes to normal cholesterol uptake in macrophages; therefore, in the absence of MARCO, macrophages are more susceptible to a greater inflammatory response by particulates known to cause NLRP3 inflammasome activation and the effect is due to increased LMP.…”
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69
Immune Responses to Tissue-Restricted Nonmajor Histocompatibility Complex Antigens in Allograft Rejection
Published 2017-01-01“…Chronic diseases that result in end-stage organ damage cause inflammation, which can reveal sequestered self-antigens (SAgs) in that organ and trigger autoimmunity. …”
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70
Influence of Solvent on the Component Composition and Antioxidant Properties of Apricot Cake (Prunus armeniaca L.) Extracts
Published 2020-01-01“…In the obtained extracts, identification of the sequestered chemically active compounds was carried out by means of chromatography, mass spectrometry, and IR and UV spectrometry, and the extracts were evaluated on antioxidant properties. …”
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71
Functions of BCL-XL at the Interface between Cell Death and Metabolism
Published 2013-01-01“…In addition, BCL-XL has been suggested to exert cytoprotective functions by sequestering a cytosolic pool of the pro-apoptotic transcription factor p53 and by binding to the voltage-dependent anion channel 1 (VDAC1), thereby inhibiting the so-called mitochondrial permeability transition (MPT). …”
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72
The Amazonian mangrove systems accumulate and release dissolved neodymium and hafnium to the oceans
Published 2025-01-01“…Abstract Mangroves are essential tropical ecosystems nurturing a wide range of marine biodiversity and counteracting global warming by sequestering atmospheric carbon dioxide. Hence, the export mechanisms and fluxes of particulate and dissolved organic carbon and trace elements from mangroves directly influence coastal productivity, the global carbon cycle and thus global climate, which are, however, not well constrained. …”
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73
Unveiling the CO2 adsorption capabilities of carbon nanostructures from biomass waste: An extensive review
Published 2025-03-01“…Though there are many advanced technologies for sequestering CO2 from the atmospheric air. The most favourable route is using activated carbon derived from biomass. …”
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74
The Effects of Rape Residue Mulching on Net Global Warming Potential and Greenhouse Gas Intensity from No-Tillage Paddy Fields
Published 2014-01-01“…During a rice-growing season, residue mulching treatments sequestered significantly more organic C from 687 kg C ha−1 season−1 to 1654 kg C ha−1 season−1 than no residue treatment. …”
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75
The N-Terminal Domain of Y-Box Binding Protein-1 Induces Cell Cycle Arrest in G2/M Phase by Binding to Cyclin D1
Published 2009-01-01“…We further demonstrated that this N-terminal 77 amino acid domain of YB-1 sequesters cyclin D1 in the cytoplasm of cells at G2/M phase of cell cycle. …”
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76
Particle-size fractions-dependent extracellular enzyme activity in sediments and implications for resource allocation in a subtropical mangrove ecosystem
Published 2015-01-01“…Thus, these results provided a means to assess the availability of different nutrients (C, N, and P) during decomposition of sediment organic matter (SOM), and thus helping to better manage the subtropical mangrove ecosystems to sequester C into SOM.…”
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77
Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice
Published 2016-01-01“…The atypical chemokine receptor ACKR2 is a chemokine scavenger receptor which binds and sequesters many inflammatory CC chemokines but does not transduce typical G-protein mediated signaling events. …”
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78
Glucocorticoid receptor: translocation from the cytoplasm to the nuclei, chromatin and intranuclear chaperone cycles
Published 2015-07-01“…In the absence of any ligand, GR resides in the cytoplasm where it is sequestered in a multimeric chaperone complex consisting of hsp90, hsp70, p23, Hop, FKBP51, FKBP52, etc. …”
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79
Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis.
Published 2024-12-01“…Aggregated, phosphorylated TDP-43 may contribute to disease phenotypes; alternatively, TDP-43 aggregation may be a protective cellular response sequestering toxic protein away from the rest of the cell. …”
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80
An analysis of the current and potential market opportunities for hempseed and fibre: the case of Scotland?
Published 2025-01-01“…Results The results of this study show that the opportunities from hemp seed and fibre are vast: hemp can sequester more carbon dioxide than traditional crops can, improve soil biodiversity, extract toxins from soil through phytoremediation, be used as an eco-friendly insecticide and pesticide, and provide an excellent source of protein, fibre and micronutrient vitamins and minerals, as well as a range of bioactive phytochemicals. …”
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