Role of sirtuins in epigenetic regulation and aging control by E. M. Samoilova, S. E. Romanov, D.  A. Chudakova, P. P. Laktionov

“…As is expected, the activity of sirtuin proteins affects the manifestation of classic signs of aging in the body, such as cellular senescence, metabolic disorders, mitochondrial dysfunction, genomic instability, and the disruption of epigenetic regulation. …”
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The role of SASP in ischemic stroke: a deep dive into cellular mechanisms by Dong Xie, Yang Liu, Fang-Biao Xu, Jin-Sheng Zhang

“…Aging, a prominent risk factor, implicates the senescence-associated secretory phenotype (SASP) in IS pathogenesis. …”
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Impact of Using Near Real-Time Green Vegetation Fraction in Noah Land Surface Model of NOAA NCEP on Numerical Weather Predictions by Li Fang, Xiwu Zhan, Christopher R. Hain, Jicheng Liu

“…The RMSE in SM estimates from the off-line Noah model is reduced by around 1.0% (1.41%) during the green-up phase and by 1.48% (2.24%) over the senescence phase for the surface (root zone) SM simulations. …”
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Age-associated alterations in immune and inflammatory responses in captive olive baboons (Papio anubis) by Michele M. Mulholland, Bharti P. Nehete, Ashley DeLise, Angela M. Achorn, Lisa M. Pytka, Pramod N. Nehete, Pramod N. Nehete

“…These findings suggest that the olive baboon is a suitable model for biogerontology research, immune senescence, and development of vaccines. Though there are phenotypic and functional similarities between baboons and humans, specific differences exist in immune cell expression and immune function of lymphocytes that should be considered for better experimental outcomes in the development of therapeutics and restoring innate and adaptive immune function in aged individuals.…”
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Changes in the transcriptome of the prefrontal cortex of OXYS rats as the signs of Alzheimer’s disease development by N. A. Stefanova, E. E. Korbolina, N. I. Ershov, E. I. Rogaev, N. G. Kolosova

“…Recently, we showed that senescence-accelerated OXYS rats represent a promis­ing model of AD; in these rats, accelerated aging of the brain is accompanied by the typical signs of AD: degenerative alterations and death of neurons, a de­crease in synaptic density, mitochondrial dysfunction, hyperphosphorylation of the tau protein, an increased level of amyloid β (Aβ1–42), and the formation of amyloid plaques. …”
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Tomato Quality during Short-Term Storage Assessed by Colour and Electronic Nose by Valeria Messina, Pía Guadalupe Domínguez, Ana Maria Sancho, Noemi Walsöe de Reca, Fernando Carrari, Gabriela Grigioni

“…Olfactory system measurements were coupled with colour values. Odour profile and senescence parameters were carried out at 7-day intervals. …”
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Differential expression and localization of expansins in Arabidopsis shoots: implications for cell wall dynamics and drought tolerance by Darina Balkova, Katerina Mala, Jan Hejatko, Jan Hejatko, Klara Panzarova, Lamis Abdelhakim, Barbora Pleskacova, Marketa Samalova, Marketa Samalova

“…The induced EXPA1 line also displayed significant morphological changes in shoots, including smaller plant size, delayed senescence, and structural alterations in vascular tissues. …”
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Fieldwork on animals living in extreme conditions as a source of biomedical innovation by Yvon Le Maho, Aurélie Tasiemski, Fabrice Bertile, Philippe Bulet

“…We recommend focusing on the major threats to global human health today, which wild animals appear to resist particularly well, such as antibioresistance and diseases associated with lifestyle and senescence.…”
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Evaluation of fertilization strategies for the establishment and productivity of Xaraés grass by N. M. Lage Filho, A. R. Lopes, D. F. Araújo, V. H. M. Macedo, C. Faturi, T. C. Silva, A. C. Rêgo, W. L. Silva, F. N. Domingues

“…In experiment 1 the morphogenic characteristics of the plant were evaluated, in the second the structure and dry mass production of the aerial part and roots of Xaraés grass were evaluated Higher (P<0.05) rates of leaf elongation and appearance, stem elongation, and leaf senescence, in addition to higher (P<0.05) tiller densities and dry mass production, were obtained in strategy 2 than in the others. …”
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Extreme-phenotype genome-wide association study (XP-GWAS) of powdery mildew race 2 W tolerance in the USDA Citrullus germplasm collection by Sandra E. Branham, Venkata Rao Ganaparthi, W. Patrick Wechter, Younghoon Park, Todd Wehner, Angela Davis, Antonia Tetteh, Laura Massey, Sue Hammar, Rebecca Grumet, Shaker Kousik, Amnon Levi

“…Abstract Powdery mildew outbreaks, caused by Podosphaera xanthii, cause reduced watermelon yields as the plants produce fewer and smaller fruits due to premature leaf senescence. The reduced leaf canopy can decrease fruit quality due to sun scalding. …”
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Phytoalexin deficient 4 is associated with the lesion mimic trait in watermelon clalm mutant (Citrullus lanatus) by Jiale Shi, Congji Yang, Yuanyuan Qin, Qingqing Liu, Shengqi Hua, Defeng Wu, Wei Dong

“…The predicted target gene, ClCG04G001930, encodes a Phytoalexin deficient 4 (PAD4), a protein that plays an important regulatory role in leaf senescence in many plant species. According to quantitative real-time PCR analysis, the expression level of ClCG04G001930 was significantly higher in the clalm mutant than in normal watermelon. …”
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Non-thermal plasma as promising anti-cancer therapy against bladder cancer by inducing DNA damage and cell cycle arrest by Jojanneke Stoof, Zakaria Kalmoua, Ana Sobota, Ruud H. Brakenhoff, Marijke Stigter, Thang V. Pham, Sander R. Piersma, Alex Henneman, Tonny Lagerweij, Richard de Goeij-de Haas, R. Jeroen A. van Moorselaar, Connie R. Jimenez, Irene V. Bijnsdorp

“…PAS treatment exerts a potent cytotoxic effect through the production of intracellular reactive oxygen species, resulting in DNA damage and subsequent induction of G1 cell cycle arrest/senescence. This is induced via upregulation of cell cycle checkpoint signalling and DNA damage repair pathways using LC-M/MS-based phospho-proteomics. …”
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TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms by Nicholas L. Calistri, Tiera A. Liby, Zhi Hu, Hongmei Zhang, Mark A. Dane, Sean M. Gross, Laura M. Heiser

“…We found that escalating doses of paclitaxel resulted in multinucleation, promotion of senescence, and initiation of DNA damage induced apoptosis. …”
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Phenological Characteristics and Environmental Factor Associations in Open-Field Cultivation of Pepino on the Qinghai-Tibet Plateau by Zhichao Hou, Cheng Si, Qiwen Zhong, Haiwang Zhang, Ziran Guo, Guangnan Zhang, Dengkui Shao, Shipeng Yang

“…Our study delineated a comprehensive set of growth stages, covering nine primary stages from vegetative to reproductive, ending in complete senescence. Utilizing the BBCH growth stage scale, we documented and standardized the nutritional and reproductive growth stages of pepino at four distinct locations on the Qinghai-Tibet Plateau. …”
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Peptide hormones in plants by Zhenbiao Zhang, Huibin Han, Junxiang Zhao, Zhiwen Liu, Lei Deng, Liuji Wu, Junpeng Niu, Yongfeng Guo, Guodong Wang, Xiaoping Gou, Chao Li, Chuanyou Li, Chun-Ming Liu

“…The roles of peptide hormones are implicated in, but not limited to, processes such as self-incompatibility, pollination, fertilization, embryogenesis, endosperm development, stem cell regulation, plant architecture, tissue differentiation, organogenesis, dehiscence, senescence, plant-pathogen and plant-insect interactions, and stress responses. …”
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Compilation and functional classification of telomere length-associated genes in humans and other animal species by E. V. Ignatieva, N. S. Yudin, D. M. Larkin

“…Telomere shortening initiates cellular senescence, which can lead to degeneration and atrophy of tissues, so the process is associated with a reduction in life expectancy and predisposition to a number of diseases. …”
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Culture dependent and independent approaches reveal the role of specific bacteria in human skin aging by Jing‐jing Xia, Qian Zhong, Zhi‐ming Li, Qing‐zhen Wei, Liu‐yi‐qi Jiang, Cheng Duan, Hui‐jue Jia, Yi‐mei Tan, Lian‐yi Han, Jean Krutmann, Jiucun Wang, Xiao Liu

“…Moraxella osloensis isolated from healthy skin regulates collagen metabolism and extracellular matrix assembly, and promotes cell senescence in human keratinocytes and fibroblasts, making it potentially applicable in the development of antiaging interventions.…”
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1-Methylcyclopropene Delays Browning and Maintains Aroma in Fresh-Cut Nectarines by Rui Zhang, Ze Miao, Shuang Xie, Jiao Li, Sheng Tao, Yuqian Jiang, Lingling Pang, Lihua Duan, Xihong Li

“…The color and aroma of nectarines experience adverse effects from cutting, resulting in the fast senescence of fruit tissue. Therefore, 1-methylcyclopropene (1-MCP) was used to treat postharvest nectarines before cutting, and its effect on the surface browning and aroma alteration were investigated. …”
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The Efficacy of Functional and Traditional Exercise on the Body Composition and Determinants of Physical Fitness of Older Women: A Randomized Crossover Trial by Antônio Gomes de Resende-Neto, José Carlos Aragão-Santos, Bruna Caroline Oliveira-Andrade, Alan Bruno Silva Vasconcelos, Clodoaldo Antônio De Sá, Felipe José Aidar, Josimari Melo DeSantana, Eduardo Lusa Cadore, Marzo Edir Da Silva-Grigoletto

“…The programs used are equally effective in increasing physical fitness for daily activities in physically active older women, and therefore, they may be complementary to combat some of the deleterious effects of senescence.…”
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p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment by Darya Yanushko, Beatriz German Falcon, Rana El Bizri, Despoina Pervizou, Robin Dolgos, Céline Keime, Tao Ye, Christelle Thibault-Carpentier, Clementine Le Magnen, Sandrine Henri, Gilles Laverny, Daniel Metzger

“…Using genetically engineered mice, we show that Trp53 deficiency in Pten-null prostatic epithelial cells (PECs) does not impact early cell proliferation and neoplasia formation, nor growth arrest and senescence entry at a later time. However, Trp53-deficiency enhances invasive adenocarcinoma development and promotes metastatic cell dissemination. …”
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