Life stage hypothesis modeling determines insect vulnerability during developmental life stages to climate extremes by J. Simone Durney, Diane M. Debinski, Stephen F. Matter

“…We speculate that higher temperatures during the spring ephemeral host plant's flowering, and P. clodius' larval stage, may lead to earlier plant senescence and lower P. clodius growth. Because Parnassius butterflies are well studied from a global perspective, results may aid in understanding the potential indicator life stages of other insect species in montane environments to climatic changes. …”
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A Colorado Front Range grassland exhibits decreasing dominance of cheatgrass (Bromus tectorum) over time by Janet S. Prevéy, Timothy R. Seastedt

“…In grasslands of the Front Range of Colorado, a region experiencing a “spring/summer‐wet” precipitation pattern, cheatgrass can exploit early‐season soil moisture, but moderate rainfall continues into the growing season beyond the time of cheatgrass senescence. In this study, we measured how cheatgrass dominance changed over a 13‐year interval in a disturbed meadow along the Front Range of Colorado with a “spring/summer‐wet” precipitation pattern. …”
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Copolyamide-Based Modified Atmosphere Packaging Attenuates Phenolic Degradation and Maintains Postharvest Quality of <i>Rubus</i> Berries by Hafiz Muhammad Shoaib Shah, Zora Singh, Mahmood Ul Hasan, Eben Afrifa-Yamoah, Andrew Woodward

“…The highly perishable nature of <i>Rubus</i> berries, particularly their susceptibility to water loss and earlier senescence, significantly limits their shelf life. In this study, we investigated the mechanistic role of modified atmosphere packaging (MAP) on the physiochemical quality, phenolic metabolism, and antioxidant potential of blackberries and raspberries during cold storage (2 ± 1 °C) for 12 and 10 days, respectively. …”
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Synthesis of Arginase Inhibitors: An Overview by Maria Cristina Molaro, Chiara Battisegola, Marica Erminia Schiano, Mariacristina Failla, Maria Grazia Rimoli, Loretta Lazzarato, Konstantin Chegaev, Federica Sodano

“…It also mediates different cellular functions and processes such as proliferation, senescence, apoptosis, autophagy, and inflammatory responses in various cell types. …”
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BONE MARROW MICROENVIRONMENT INVOLVEMENT IN T-MN: FOCUS ON MESENCHYMAL STEM CELLS by Maria Teresa Voso, Giulia Falconi, Emiliano Fabiani

“…Over the last decade, it has been shown that BM-MSC isolated from patients with de novo and therapy-related MN exhibit decreased proliferative and clonogenic capacity, altered morphology, increased senescence, defective osteogenic differentiation potential, impaired immune-regulatory properties, and reduced ability to support HSC growth and differentiation, as compared to normal BM-MSC. …”
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Citrulline – The Powerhouse Nutrient for Cardiometabolic and Brain Health by Daria Pedrycz, Mateusz Drabczyk, Emilia Pedrycz, Karolina Karoń, Grzegorz Drapała, Wojciech Grabowski, Łukasz Karoń, Anna Zygmunt, Sławomir Karoń

“…Emerging evidence suggests its potential in delaying endothelial senescence and preventing ferroptosis, establishing its role in vascular and neuroprotective strategies. …”
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Nicotinamide adenine dinucleotide supplementation fails to enhance anesthetic recovery in rodents by Candida L. Goodnough, July Montoya, Erica B. Cartusciello, Erin L. Floranda, Eric R. Gross

“…Abstract Nicotinamide Adenine Dinucleotide (NAD+) is implicated in bioenergetics, DNA repair, and senescence. Depletion of NAD+ is associated with aging and neurodegenerative disease, prompting a growing interest in NAD+ supplementation. …”
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Metabolite-Sensing Receptors: Emerging Targets for Modulating Chronic Pain Pathways by Ciprian Pușcașu, Corina Andrei, Octavian Tudorel Olaru, Anca Zanfirescu

“…TGR5, activated by bile acids, regulates inflammation and cellular senescence through pathways like NF-κB and p38. These receptors are promising therapeutic targets in chronic pain, addressing the metabolic and inflammatory factors underlying nociceptive sensitization and tissue degeneration. …”
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Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation-Related Tumorigenesis via Modulating Macrophages by Yanxia Fu, Jun Li, Mengdi Li, Junfeng Xu, Zheng Rong, Fangli Ren, Yinyin Wang, Jianqiu Sheng, Zhijie Chang

“…We found that HUC-MSCs cultured within 20 generations had no significant changes in proliferation, cell cycle, cellular senescence, apoptosis, and expression of mesenchymal stem cell markers. …”
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Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change by Muhammad Abubakkar Azmat, Malaika Zaheer, Muhammad Shaban, Saman Arshad, Muhammad Hasan, Alyan Ashraf, Muhammad Naeem, Aftab Ahmad, Nayla Munawar

“…., pathogen infection, nutrient deficiency, plant senescence, heat stress, drought, osmotic stress, and hypoxia induce autophagy in plants. …”
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Parity-Dependent Hemosiderin and Lipofuscin Accumulation in the Reproductively Aged Mouse Ovary by Ulises Urzua, Carlos Chacon, Renato Espinoza, Sebastián Martínez, Nicole Hernandez

“…Since lipofuscin is a widely accepted senescence marker and given the recently postulated role of lipofuscin-associated iron as a source of reactive oxygen species (ROS) in senescent cells, these findings suggest a possible pathogenic mechanism by which nulliparity contributes to an increased OC risk in the postmenopausal ovary.…”
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The Effect of the Application of Edible Coatings on or before Ultraviolet Treatment on Postharvested Longan Fruits by Mee Gie Lin, Ola Lasekan, Nazamid Saari, Siti Khairunniza-Bejo

“…Therefore, application of UV treatment followed by chitosan coating was found to be the best treatment combination for controlling enzymatic activities and reducing senescence rate of longan fruits.…”
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Farmers and Agricultural Extension Officers Perception of Striga gesnerioides (Willd.) Vatke Parasitism on Cowpea in the Upper East Region of Ghana by Peter Haruna, Aaron T. Asare, Elvis Asare-Bediako, Francis Kusi

“…Its effects on the host plants (cowpea) included stunted growth, leaf senescence, chlorosis, death of the crop, and reduced yield. …”
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Mechanistic relationship between obesity-induced inflammation triggering endothelial dysfunction and the initiation of atherosclerosis development by Richard L. Jayaraj, Elhadi H Aburawi

“…The aim of this review is to summarize the effects of obesity-related inflammation on ED and its progression to atherosclerosis, focusing on cellular senescence, vascular aging, epigenetic modifications, reactive oxygen species, vascular calcification, and gut microbiota. …”
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The relationship between mitochondrial health, telomerase activity and longitudinal telomere attrition, considering the role of chronic stress by Mauricio Guillen-Parra, Jue Lin, Aric A. Prather, Owen M. Wolkowitz, Martin Picard, Elissa S. Epel

“…Abstract Telomere attrition is a hallmark of biological aging, contributing to cellular replicative senescence. However, few studies have examined the determinants of telomere attrition in vivo in humans. …”
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The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy by M. L. Perepechaeva, A. Yu. Grishanova, E. A. Rudnitskaya, N. G. Kolosova

“…It has been shown that SkQ1 reduces clinical signs of retinopathy in senescence-accelerated OXYS rats, which are a known animal model of human age-related macular degeneration (AMD). …”
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Comparison of in vivo and in vitro preimplantation embryo development in OXYS and WAG rats by V. V. Kozhevnikova, T. N. Igonina, E. Yu.  Brusentsev, V. I. Mokrousova, E. A.  Kizilova, I. N. Rozhkova, V. A. Naprimerov, S. Ya. Amstislavsky

“…OXYS rats are the model of precocious senescence. Numerous studies addressed physiology and behavior in rats of this strain during a postnatal period of their life, however, preimplantation development in OXYS rats has not yet been investigated. …”
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Effect of three defoliation frequency treatments and drought on perennial ryegrass herbage and root growth and water‐soluble carbohydrate reserves by Katherine N. Tozer, Rose M. Greenfield, Catherine A. Cameron, Martin P. Upsdell, David E. Hume

“…Defoliation treatments comprised “VEGETATIVE”—regular defoliation based on leaf stage and trimmed to 4 cm; “FLOWERING”—no defoliation spring to anthesis; and “SENESCENT”—no defoliation spring to reproductive tiller senescence. …”
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PRMT7: A Pivotal Arginine Methyltransferase in Stem Cells and Development by Bingyuan Wang, Mingrui Zhang, Zhiguo Liu, Yulian Mu, Kui Li

“…Furthermore, we also discuss the roles of PRMT7 in cancer, adipogenesis, male reproduction, cellular stress, and cellular senescence, as well as the future perspectives of PRMT7-related studies. …”
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Mechanisms of RCD-1 pore formation and membrane bending by Keli Ren, James Daniel Farrell, Yueyue Li, Xinrui Guo, Ruipei Xie, Xin Liu, Qiaozhen Kang, Qihui Fan, Fangfu Ye, Jingjin Ding, Fang Jiao

“…Abstract Regulator of cell death-1 (RCD-1) governs the heteroallelic expression of RCD-1-1 and RCD-1-2, a pair of fungal gasdermin (GSDM)-like proteins, which prevent cytoplasmic mixing during allorecognition and safeguard against mycoparasitism, genome exploitation, and deleterious cytoplasmic elements (e.g., senescence plasmids) by effecting a form of cytolytic cell death. …”
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