Corticolimbic circuitry as a druggable target in schizophrenia spectrum disorders: a narrative review by Abigail Gee, Paola Dazzan, Anthony A. Grace, Gemma Modinos

“…Abstract Schizophrenia spectrum disorders (SSD) involve disturbances in the integration of perception, emotion and cognition. …”
Get full text

The emotional facial recognition performance of Chinese patients with schizophrenia: An event-related potentials study by Yangjun Zhang, Ding Zhao, Jianfan Wu, Lixin Lin, Jiawu Ji

Subjects: Get full text

The Association of Serum Lactoferrin Level with Psychological Symptoms, Cognition, and Executive Function in Schizophrenia Patients by Niloufar Mahdavi Hezaveh, Soheila Kianpour Rad, Yousef Semnani, Maryam Mousavi Bazaz, Abdolreza Javadi

Subjects: Get full text

Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite study by Aishwarya Raje, Abhijit R. Rozatkar, Urvakhsh Meherwan Mehta, Ritu Shrivastava, Ameya Bondre, Manaal Amir Ahmad, Anshika Malviya, Yogendra Sen, Deepak Tugnawat, Anant Bhan, Tamonud Modak, Nabagata Das, Srilakshmi Nagendra, Erlend Lane, Juan Castillo, John A. Naslund, John Torous, Soumya Choudhary

Subjects: “…Schizophrenia…”
Get full text

MO-GCN: A multi-omics graph convolutional network for discriminative analysis of schizophrenia by Haiyuan Wang, Runlin Peng, Yuanyuan Huang, Liqin Liang, Wei Wang, Baoyuan Zhu, Chenyang Gao, Minxin Guo, Jing Zhou, Hehua Li, Xiaobo Li, Yuping Ning, Fengchun Wu, Kai Wu

Subjects: “…Schizophrenia…”
Get full text

A comparative machine learning study of schizophrenia biomarkers derived from functional connectivity by Victoria Shevchenko, R. Austin Benn, Robert Scholz, Wei Wei, Carla Pallavicini, Ulysse Klatzmann, Francesco Alberti, Theodore D. Satterthwaite, Demian Wassermann, Pierre-Louis Bazin, Daniel S. Margulies

“…Abstract Functional connectivity holds promise as a biomarker of schizophrenia. Yet, the high dimensionality of predictive models trained on functional connectomes, combined with small sample sizes in clinical research, increases the risk of overfitting. …”
Get full text

Celecoxib Adjunctive Treatment to Antipsychotics in Schizophrenia: A Review of Randomized Clinical Add-On Trials by Stefano Marini, Domenico De Berardis, Federica Vellante, Rita Santacroce, Laura Orsolini, Alessandro Valchera, Gabriella Girinelli, Alessandro Carano, Michele Fornaro, Francesco Gambi, Giovanni Martinotti, Massimo Di Giannantonio

“…Schizophrenia is a severe, chronic and debilitating mental disorder. …”
Get full text

Disability and quality of life in patients with treatment-resistant schizophrenia on long- term clozapine therapy by Dhandapani Nandakumar, Ragul Ganesh, Koushik S. Deb, Raka Jain, Mamta Sood

Subjects: “…treatment-resistant schizophrenia…”
Get full text

Prevalence of obsessive-compulsive symptoms in patients with schizophrenia treated with clozapine: a scoping review by Evelyn Moreno Tarazona, Mauricio Orozco Gonzalez, Andrea La Rosa Giron, Paulo Ruiz-Grosso, Maria Lazo-Porras

Subjects: Get full text

IUPHAR Review: Alpha6-containing GABAA receptors – Novel targets for the treatment of schizophrenia by Lih-Chu Chiou, Werner Sieghart

Subjects: Get full text

Allele-specific methylation of SSTR4 associated with aging and cognitive functions in patients with schizophrenia. by Rongrong Zhao, Huihui Shi, Yanqiu Wang, Tao Jiang, Yahui Xu

“…The co-occurrence of alcohol use disorder (AUD) and schizophrenia is prevalent, with a rate of 33.7%. Previous research has suggested a genetic and epigenetic overlap between these two disorders. …”
Get full text

Long-Acting Injectable Antipsychotic Use in Patients with Schizophrenia and Criminal Justice System Encounters by Madhav P. Bhatta, Saroj Bista, Antoine C. El Khoury, Eric G. Hutzell, Neeta Tandon, Douglas Smith

“…**Background:** Nonadherence to medication is prevalent in persons diagnosed with schizophrenia, thus increasing the likelihood of relapse, poor health outcomes, hospitalization, high treatment costs, and high rates of both violent and non-violent offenses. …”
Get full text

Somatic symptoms in schizophrenia: Association with socio-demographic and clinical characteristics, disability and quality of life by Mamta Sood, Ragul Ganesh, Ananya Mahapatra, Rohit Verma, Rakesh K. Chadda

Subjects: Get full text

Maintenance Electroconvulsive Therapy in a Patient with Treatment-Resistant Paranoid Schizophrenia and Comorbid Epilepsy by Beppe Micallef-Trigona, Joseph Spiteri

“…The treatment of choice for acute schizophrenia is antipsychotic drug treatment and electroconvulsive therapy (ECT) and should only be considered as an option for treatment-resistant schizophrenia, where treatment with clozapine has already proven ineffective or intolerable. …”
Get full text

Dysexecutive Syndrome in Schizophrenia: A Cross-Cultural Comparison between Japanese and British Patients by H. Ihara, G. E. Berrios, P. J. McKenna

“…This study tested the hypothesis that the dysexecutive syndrome of schizophrenia is impervious to cultural differences. 18 Japanese and 22 British patients and 14 Japanese and 19 British control subjects were compared on the BADS (Behavioural Assessment of Dysexecutive Syndrome), a comprehensive neuropsychological assessment battery, designed for ‘ecological validity’, and other measures of frontal executive functions (EFs). …”
Get full text

Expression study of Wnt/β-catenin signaling pathway associated lncRNAs in schizophrenia by Fatemeh Manafzadeh, Behzad Baradaran, Seyed Gholamreza Noor Azar, Kamran Javidi Aghdam, Reza Dabbaghipour, Asghar Shayannia, Soudeh Ghafouri-Fard

Subjects: “…Schizophrenia…”
Get full text

Acupuncture in the Treatment of a Female Patient Suffering from Chronic Schizophrenia and Sleep Disorders by Peggy Bosch, Sabina Lim, Sujung Yeo, Sook-Hyun Lee, Heike Staudte, Maurits van den Noort

“…The use of acupuncture in the treatment of sleep disorders in patients with chronic schizophrenia is investigated. Case Presentation. We report the case of a 44-year-old female outpatient of German origin who had been suffering from long-term schizophrenia and sleep disorders. …”
Get full text

Projecting the Potential Budget Impact Analysis of Paliperidone Palmitate in Egyptian Adult Patients with Schizophrenia by Gihan Elsisi, Mohamed Ezzat, Mohamed Ramadan

“…**Background:** Schizophrenia is a serious mental disorder that has greater negative consequences on role functioning than many other severe chronic diseases. …”
Get full text

Management of Psychosis and Schizophrenia by Primary Care GPs: A Cross-Sectional Study in Spain by Jesús Sepúlveda-Muñoz, Casta Quemada González, María M. Hurtado Lara, Ángel Manuel Gutiérrez García, Celia Martí-García, José María García-Herrera Pérez-Bryan, José Miguel Morales-Asencio

“…Aim: To investigate the detection and initial management of first psychotic episodes, as well as established schizophrenia, within the primary care of the Andalusian Health System. …”
Get full text

Heart rate variability in schizophrenia: A comparative analysis before and after electroconvulsive therapy by Noriko Yoshida, Miho Miyajima, Yoko Suzuki, Eisuke Matsushima, Takafumi Watanabe, Rie Omoya, Mayo Fujiwara, Mitsuru Nakamura, Hidehiko Takahashi, Takashi Takeuchi

Subjects: Get full text