Reviewing the current treatment approaches for bullous pemphigoid – analysis of literature by Julia Nowak, Agnieszka Najdek, Daria Oleksy, Dawid Komada, Urszula Kaczmarska, Aleksandra Woźniak, Michał Jakub Cioch, Marcin Mycyk, Kamil Hermanowicz, Katarzyna Doman

“…BP significantly impacts patients’ quality of life due to painful, pruritic skin lesions and is associated with a higher prevalence of psychiatric comorbidities, such as schizophrenia. BP increases the risk of complications, including pulmonary embolism and pneumonia, and is linked to high mortality. …”
Get full text

Neuroprotection and Functional Recovery Associated with Decreased Microglial Activation Following Selective Activation of mGluR2/3 Receptors in a Rodent Model of Parkinson's Diseas... by Hugh Chan, Helen Paur, Anthony C. Vernon, Virginia Zabarsky, Krishna P. Datla, Martin J. Croucher, David T. Dexter

“…Clinical trials have demonstrated positive proof of efficacy of dual metabotropic glutamate receptor 2/3 (mGluR2/3) agonists in both anxiety and schizophrenia. Importantly, evidence suggests that these drugs may also be neuroprotective against glutamate excitotoxicity, implicated in the pathogenesis of Parkinson's disease (PD). …”
Get full text

Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes by Yukiko Kikuchi, Mohammed Uddin, Joris A. Veltman, Sara Wells, Christopher Morris, Marc Woodbury-Smith

“…Constraint was also observed across genes associated with intellectual disability (p = 1.1 × 10− 46), epilepsy (p = 2.1 × 10− 33) and schizophrenia (p = 4.2 × 10− 45), and for an overlapping neurodevelopmental gene set (p = 4.0 × 10− 10). …”
Get full text

Employing the concept of stacking ensemble learning to generate deep dream images using multiple CNN variants by Lafta Alkhazraji, Ayad R. Abbas, Abeer S. Jamil, Zahraa Saddi Kadhim, Wissam Alkhazraji, Sabah Abdulazeez Jebur, Bassam Noori Shaker, Mohammed Abdallazez Mohammed, Mohanad A. Mohammed, Basim Mohammed Al-Araji, Abdulkareem Z. Mohmmed, Wasiq Khan, Bilal Khan, Abir Jaafar Hussain

“…Addiction and adverse effects resulting from schizophrenia are rapidly becoming a global issue, necessitating the development of advanced approaches that can provide support to psychiatrists and psychologists to understand and replicate the hallucinations and imagery experienced by patients. …”
Get full text

Timing of risk factors, prodromal features, and comorbidities of dementia from a large health claims case–control study by Stefan Teipel, Manas Akmatov, Bernhard Michalowsky, Steffi Riedel-Heller, Jens Bohlken, Jakob Holstiege

“…The greatest risk, with odds ratios greater than 2.5, was conferred by delirium, memory impairment, mental retardation, personality and behavioral disorders, sensory disorders, schizophrenia, and psychosis. Cancer was associated with a reduced risk of dementia. …”
Get full text

Breast cancer patients with a pre-existing mental illness are less likely to receive guideline-recommended cancer treatment: A systematic review and meta-analysis by Katie Elliott, Emily Haworth, Iakov Bolnykh, R. Hamish McAllister-Williams, Alastair Greystoke, Adam Todd, Linda Sharp

“…The included studies were predominantly from high-income countries, and compared breast cancer treatment in patients with and without pre-existing mental illnesses including anxiety, mood disorders, schizophrenia and psychotic disorders, and neurodevelopmental disorders. …”
Get full text

Role of apoptosis genes in aggression revealed using combined analysis of ANDSystem gene networks, expression and genomic data in grey rats with aggressive behavior by A. O. Bragin, O. V. Saik, I. V. Chadaeva, P. S. Demenkov, A. L. Markel, Yu. L. Orlov, E. I.  Rogaev, I. N. Lavrik, V. A. Ivanisenko

“…Increased aggression is observed in a number of diseases ( schizophrenia, bipolar disorder, brain degenerative disorders). …”
Get full text

Investigating resting-state functional connectivity changes within procedural memory network across neuropsychiatric disorders using fMRI by Mahdi Mohammadkhanloo, Mohammad Pooyan, Hamid Sharini, Mitra Yousefpour

“…Abstract Background Cognitive networks impairments are common in neuropsychiatric disorders like Attention Deficit Hyperactivity Disorder (ADHD), bipolar disorder (BD), and schizophrenia (SZ). While previous research has focused on specific brain regions, the role of the procedural memory as a type of long-term memory to examine cognitive networks impairments in these disorders remains unclear. …”
Get full text

THE PLANNING AND ORGANIZATION OF ECT TREATMENTS IN FINLAND – RESULTS FROM A NATIONAL SURVEY by SAANA KARTTUNEN, LAURI VIRTANEN, ANU HOLM, NIKO SEPPÄLÄ, PETRI SUMIA, ERIKA JÄÄSKELÄINEN, KAIJA JÄRVENTAUSTA

“…The length of the acute ECT varied from 3 to 16 treatments, with a somewhat different number of treatments for schizophrenia and depression. ECT maintenance treatments were given in all 22 units, with varying protocols. …”
Get full text

A Review on Current Aspects of Curcumin-Based Effects in Relation to Neurodegenerative, Neuroinflammatory and Cerebrovascular Diseases by Claudia-Andreea Moldoveanu, Maria Tomoaia-Cotisel, Alexandra Sevastre-Berghian, Gheorghe Tomoaia, Aurora Mocanu, Csaba Pal-Racz, Vlad-Alexandru Toma, Ioana Roman, Madalina-Anca Ujica, Lucian-Cristian Pop

“…This review explores cellular and molecular current aspects, of curcumin-based effects with an emphasis on curcumin’s metabolism and its impact on pathological conditions, such as neurodegenerative diseases, schizophrenia, and cerebral angiopathy. It also highlights the limitations posed by curcumin’s poor bioavailability and discusses ongoing efforts to surpass these impediments to harness the full therapeutic potential of curcumin in neurological disorders.…”
Get full text

Utility of Consumer-Grade Wearable Devices for Inferring Physical and Mental Health Outcomes in Severe Mental Illness: Systematic Review by Lamiece Hassan, Alyssa Milton, Chelsea Sawyer, Alexander J Casson, John Torous, Alan Davies, Bernalyn Ruiz-Yu, Joseph Firth

“…ObjectiveThis study aims to examine the utility of data from consumer-grade, digital, wearable devices (including smartphones or wrist-worn devices) for remotely monitoring or predicting changes in mental or physical health among adults with schizophrenia or bipolar disorder. Studies were included that passively collected physiological data (including sleep duration, heart rate, sleep and wake patterns, or physical activity) for at least 3 days. …”
Get full text

Modifiable factors for irritable bowel syndrome: evidence from Mendelian randomisation approach by Jinling Tang, Zhirong Yang, Shanshan Wu, Feng Sha, Tengfei Lin, Di Liu, Meiling Cao, Yiwen Jiang, Weijie Cao, Fuxiao Li

“…Additionally, smoking, alcohol frequency, college or university degree, intelligence, childhood maltreatment, frailty index, diverticular disease of the intestine and schizophrenia were suggestively associated with IBS. …”
Get full text

Neuroinflammation mediates the progression of neonate hypoxia-ischemia brain damage to Alzheimer’s disease: a bioinformatics and experimental study by Shengjie Zhang, Ruqiu Zhang, Zhaoqin Chen, Zihan Shao, An Li, Fan Li, Fang Huang

“…Gene-disease association analysis shows Mammary Neoplasms, Neoplasm Metastasis, Schizophrenia, and Brain Ischemia diseases are the most relevant to the hub proteins we identified. …”
Get full text

Approaches for difficult-to-induce-seizures electroconvulsive therapy cases (DEC): a Japanese expert consensus by Yoshiteru Takekita, Taro Suwa, Kazuyuki Yasuda, Hirotsugu Kawashima, Wataru Omori, Naoki Kurimoto, Takashi Tsuboi, Takamasa Noda, Nobuatsu Aoki, Ken Wada, Ken Inada, Minoru Takebayash, Expert Consensus Development Working Group, Electroconvulsive Therapy Committee, Japanese Society of General Hospital Psychiatry

“…The results of rating approaches for patients with mood disorders and schizophrenia were similar, with differences observed among the approaches for patients with catatonia, high risk of cognitive impairment, and cardiovascular events. …”
Get full text

In silico analysis of hub genes and regulatory networks implicates the putamen in non-motor Parkinson’s disease disorders by Stephen Tunmise Akanbi, Joshua Ayodele Yusuf, Thompson Oluwaferanmi Ayandele, Dayo Samson Oladipupo, Darasimi Racheal Olorunlowu, Blessing Dorcas Olawuyi, Joshua Oluwafisayo Adepoju, Dolapo Emmanuel Opasina, Elizabeth Kehinde Opoola, Uchenna Victor Ugwuanyi, Olufunto Omodele Adeleye

“…Conclusions Our findings revealed close associations between the hub genes of PD putamen and non-motor symptoms of PD such as major depressive disorder, mood disorders and schizophrenia. These findings may provide a new direction for developing therapy for non-motor symptoms of PD and wet lab research is encouraged.…”
Get full text

Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study by Li R, Li J, Ji SS, Li D, Chu L, Zhang J, Sun X, Luo X, Zhang Y

“…Ru Li,1,* Jiaxin Li,1,* Shiyi Suzy Ji,2 Dazhi Li,1 Lijun Chu,1 Jian Zhang,1 Xia Sun,1 Xingguang Luo,3 Yong Zhang1 1Unit of Bipolar Disorder, Tianjin Anding Hospital, Tianjin, People’s Republic of China; 2Department of Counseling and Clinical Psychology, Teachers College, Columbia University, NY, New York, USA; 3Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA*These authors contributed equally to this workCorrespondence: Yong Zhang, Unit of Bipolar Disorder, Tianjin Anding Hospital, 13 Liulin Road, Hexi District, Tianjin, 300222, People’s Republic of China, Tel/Fax +86 22 8818 8258, Email zhangyong@tjmhc.comPurpose: We aimed to verify the impact of functional remediation (FR) on serum brain-derived neurotrophic factor (BDNF) and tyrosine kinase receptor B (TrkB) levels, to explore the biomechanism of FR intervention in patients with euthymic bipolar disorder (BD).Patients and Methods: This is a randomized controlled, 12-week intervention study with participants randomized into the FR group (n=39) and the treatment as usual group (TAU, n=42) at the 1∶1 ratio. 17-Hamilton Depression Rating Scale-17 (HDRS-17), Young Mania Rating Scale (YMRS), and Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB) were used to assess affective symptoms and cognitive functioning both at baseline and week 12, respectively. …”
Get full text

The interaction network and potential clinical effectiveness of dimensional psychopathology phenotyping based on EMR: a Bayesian network approach by Jianqing Qiu, Ting Zhu, Ke Qin, Wei Zhang

“…Therefore, we employed unsupervised learning to translate five domains of eRDoC scores derived from electronic medical records (EMR) of patients diagnosed with Major Depressive Disorder (MDD), Schizophrenia (SCZ), and Bipolar Disorder (BD) at West China Hospital between 2008 and 2021. …”
Get full text

Brain Age Prediction Using a Lightweight Convolutional Neural Network by Fatma Eltashani, Mario Parreno-Centeno, James H. Cole, Joao Paulo Papa, Fumie Costen

“…Studies based on brain magnetic resonance images showed a strong relationship between the brain ageing process and accelerated brain atrophy, suggesting using brain age prediction models for early diagnosis of neurodegenerative disorders, such as Parkinson’s, Schizophrenia, and Alzheimer’s disease. However, data availability, acquisition protocols diversity and models’ computational complexity remain limiting factors for clinical adoption. …”
Get full text

Beyond metabolic messengers: Bile acids and TGR5 as pharmacotherapeutic intervention for psychiatric disorders by Arief Gunawan Darmanto, Ting-Lin Yen, Jing-Shiun Jan, Tran Thanh Duy Linh, Rajeev Taliyan, Chih-Hao Yang, Joen-Rong Sheu

“…We detail the synthesis and systemic functions of bile acids, their transformation by gut microbiota, and their impact across various neuropsychiatric disorders, including major depressive disorder, general anxiety disorder, schizophrenia, autism spectrum disorder, and bipolar disorder. …”
Get full text

Omega-3 Fatty Acids: Key Players in Cognitive Function and Brain Health by Wiktoria Wesołowska, Emilia Bachoń, Michalina Doligalska, Aleksandra Stremel, Agnieszka Leszyńska, Julia Linke, Zuzanna Bałoniak, Dominika Kozłowska, Julia Bałoniak, Weronika Tuszyńska

“…In mental health, omega-3s can help reduce symptoms of depression and schizophrenia, although effectiveness depends on dosage and the EPA to DHA ratio. …”
Get full text