Causal associations between circulating protein ratios and drug resistance in papillary thyroid cancer: a Mendelian randomization study by Jiaqin Deng, Ming Yu, Yihua Gu, Yeqian Lai, Lihong Qiu

“…Seven CPLRs, such as REG1A/TFF3 and LAT/SPARC, were associated with reduced PTC risk, potentially reflecting protective mechanisms. …”
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Radiation Belt Model Including Semi‐Annual Variation and Solar Driving (Sentinel) by C. Katsavrias, S. Aminalragia‐Giamini, C. Papadimitriou, I. A. Daglis, I. Sandberg, P. Jiggens

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Transport and profile broadening in the private flux region of ASDEX upgrade and role for power exhaust by D. Brida, G. Grenfell, O. Grover, D. Silvagni, M. Faitsch, U. Stroth, the ASDEX Upgrade Team, the EUROfusion Tokamak Exploitation Team

“…For the tokamaks ITER and SPARC the model predicts PFR widths below 0.3 mm.…”
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基于生物信息学途径探究载脂蛋白 H 在肝衰竭中的功能及作用机制 by 曹静, 龚娇, 李新华, 李丹阳, 于明雪, 崇雨田, 揭育胜

“…蛋白质相互作用网络分析发现10个枢纽基因分别为：KNG1、IGF1、SPARC、APOH、CLU、SERPING1、TGFB2、CDC37L1、PCYOX1L和APOOL。…”
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Boosting Parallel Applications Performance on Applying DIM Technique in a Multiprocessing Environment by Mateus B. Rutzig, Antonio C. S. Beck, Felipe Madruga, Marco A. Alves, Henrique C. Freitas, Nicolas Maillard, Philippe O. A. Navaux, Luigi Carro

“…We have successfully coupled a dynamic reconfigurable system to an SPARC-based multiprocessor and obtained performance gains of up to 40%, even for applications that show a great level of parallelism at thread level.…”
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Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascend... by Annette Janus, Daniël Dumas, Juliette Le Douce, Sébastien Marie, Giuseppe Pasculli, Pauline Bambury, Sighild Lemarchant, Philip Kremer, Yann Godfrin

“…In silico data modelling revealed salient pharmacokinetic-pharmacodynamic relationships, including reduction of claudin-5, neurofilament light chain, and SPARC-like protein 1 release, and degradation of homocysteine. …”
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Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis by Yuan Liu, Wacili Da, Ming-Jie Xu, Chao-Xin Xiao, Tao Deng, Sheng-Liang Zhou, Xiao-Ting Chen, Yao-Jia Zhou, Li Tang, Yong Nie, Yi Zeng, Hui-Qi Xie, Bin Shen

“…The number of H-type vessels was increased in the subchondral bone, recruiting osteoprogenitor cells and facilitating osteogenesis in KOA mice. Sparc + osteoblasts have negatively regulated bone mineralization and osteoblastic differentiation, aggravated the pathological remodeling of subchondral bone, and promoted the progression of KOA. …”
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Molecular Mechanism of Local Drug Delivery with Paclitaxel-Eluting Membranes in Biliary and Pancreatic Cancer: New Application for an Old Drug by Sookhee Bang, Sung Ill Jang, Su Yeon Lee, Yi-Yong Baek, Jieun Yun, Soo Jin Oh, Chang Woo Lee, Eun Ae Jo, Kun Na, Sugeun Yang, Don Haeng Lee, Dong Ki Lee

“…Moreover, implantation of the PEM inhibited tumor-stromal interaction-related expression of proteins such as CD44, SPARC, matrix metalloproteinase-2, and vimentin. …”
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The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome by Ali Kemal Oguz, Cagdas Sahap Oygur, Bala Gur Dedeoglu, Irem Dogan Turacli, Sibel Serin Kilicoglu, Ihsan Ergun

“…., <i>CLU</i>, <i>PF4</i>, <i>PPBP</i>, <i>SPARC</i>, and <i>THBS1</i>). Functional enrichment analysis documented significantly enriched terms related to platelets, including but not limited to “platelet reactivity”, “platelet degranulation”, “platelet aggregation”, and “platelet activation”. …”
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Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes by Jaroslaw Szczyrba, Volker Jung, Michaela Beitzinger, Elke Nolte, Sven Wach, Martin Hart, Sandra Sapich, Marc Wiesehöfer, Helge Taubert, Gunther Wennemuth, Norbert Eichner, Thomas Stempfl, Bernd Wullich, Gunter Meister, Friedrich A. Grässer

“…We demonstrate that the mRNAs of the death effector domain-containing protein (DEDD), the tumor necrosis factor receptor superfamily, member 10b protein (TNFRSF10B), the tumor protein p53 inducible nuclear protein 1 (TP53INP1), and the secreted protein, acidic, cysteine-rich (SPARC; osteonectin) are regulated by miRNAs miR-148a, miR-20a, miR-24, and miR-29a/b, respectively. …”
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Attention-Guided Shared Hybrid Network for Enhanced Land Cover Segmentation by Yinbing Jiang, Linfeng Shi, Xinyu Fan

“…Extensive experiments conducted on benchmark land cover datasets, including WHDLD, GID-15, and L8SPARCS, demonstrate that AGSHN significantly outperforms existing state-of-the-art methods in segmentation accuracy.…”
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Cloud and Cloud Shadow Detection for Multi-Modal Imagery With Gap-Filling Applications by Keunhoo Cho, Seongwook Park, Boram Seong, Seongwhan Lee, Jae-Pil Park

“…When applied to Landsat-8 SPARCS and Sentinel-2 CloudSEN12 test datasets, it also showed high performance, with mean F1 scores of 0.741 and 0.8, respectively, effectively indicating that multi-modal CCS detection can be successfully implemented. …”
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