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  1. 2481

    KYNU as a Biomarker of Tumor-Associated Macrophages and Correlates with Immunosuppressive Microenvironment and Poor Prognosis in Gastric Cancer by Kaiyu Shen, Binyu Chen, Liu Yang, Wencang Gao

    Published 2023-01-01
    “…Clinical features and survival analysis indicated that high KYNU expression was associated with poor clinical phenotypes and prognosis, whereas Cox analysis showed that KYNU was an independent risk factor for patients with GC. Notably, high expression of KYNU induced a poor immune microenvironment and contributed to the upregulation of immune checkpoints. …”
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  2. 2482

    The Relationship Between Cervicovaginal Infection, Human Papillomavirus Infection and Cervical Intraepithelial Neoplasia in Romanian Women by Anca Daniela Brăila, Cristian-Viorel Poalelungi, Cristina-Crenguţa Albu, Constantin Marian Damian, Laurențiu Mihai Dȋră, Andreea-Mariana Bănățeanu, Claudia Florina Bogdan-Andreescu

    Published 2025-01-01
    “…Cervical intraepithelial neoplasia (CIN) is a premalignant cervical condition closely linked to persistent high-risk HPV infection, a major risk factor for cervical cancer. This study aims to investigate the relationship between cervicovaginal infections, HPV infection, and CIN development in 94 Romanian women with cervical lesions. …”
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  3. 2483

    Hyperuricemia-induced complications: dysfunctional macrophages serve as a potential bridge by Wenyi Gu, Wenyi Gu, Jiajing Zhao, Yu Xu, Yu Xu, Yu Xu

    Published 2025-01-01
    “…Characterized by elevated levels of UA, HUA has become an independent risk factor for gout, chronic kidney disease, insulin resistance, cardiovascular disease, nonalcoholic fatty liver disease, etc. …”
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  4. 2484

    Anticoagulation Status and Outcome in Cerebral Venous Thrombosis: A Single-Center Retrospective Study from South India by Deepak Menon, Manisha Gupta, Sangeeth Thuppanattumadam Ananthasubramanian, Karthik Kulanthaivelu, Pritam Raja, Subasree Ramakrishnan, Sangeetha Seshagiri Karnam, Jitender Saini, PR Srijithesh, Girish B Kulkarni

    Published 2024-12-01
    “…Conclusions: Maintenance of an intensive level of anticoagulation may not be required in patients with CVT and may be particularly true when a transient and treatable risk factor is the provoking etiology.…”
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  5. 2485

    Vulnerability of Parkinson’s Patients to COVID-19 and Its Consequences and Effects on Them: A Systematic Review by Sorayya Rezayi, Meysam Rahmani Katigari, Leila Shahmoradi, Mehrbakhsh Nilashi

    Published 2023-01-01
    “…Despite worsening PD symptoms in the targeted population (persons with COVID-19 and Parkinson’s disease), some studies found PD to be a risk factor for more severe COVID-19 disease. There are many adverse effects during the pandemic period in PD patients such as abnormalities of motor, nonmotor functioning, clinical outcomes, activities of daily living, and other outcomes. …”
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  6. 2486

    Immunological Impacts of Diabetes on the Susceptibility of Mycobacterium tuberculosis by Birhanu Ayelign, Markos Negash, Meaza Genetu, Tadelo Wondmagegn, Tewodros Shibabaw

    Published 2019-01-01
    “…Diabetes mellitus is a major risk factor for the development of active and latent tuberculosis. …”
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  7. 2487

    The Emerging Role of Mesenchymal Stem Cells in Vascular Calcification by Changming Xie, Liu Ouyang, Jie Chen, Huanji Zhang, Pei Luo, Jingfeng Wang, Hui Huang

    Published 2019-01-01
    “…Vascular calcification (VC), characterized by hydroxyapatite crystal depositing in the vessel wall, is a common pathological condition shared by many chronic diseases and an independent risk factor for cardiovascular events. Recently, VC is regarded as an active, dynamic cell-mediated process, during which calcifying cell transition is critical. …”
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  8. 2488

    Otomycosis risk after non-suppurative middle ear surgery by Fatih Gul, Ozgenur Kocak, Ali Ozturk, Mehmet Ali Babademez

    Published 2025-03-01
    “…Objectives: The aim of this study was to investigate the risk factors that may cause postoperative otomycosis in patients undergoing Chronic Nonsuppurative Otitis Media (CNSOM) surgery. …”
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  9. 2489

    Levels of Urinary Trypsin Inhibitor and Structure of Its Chondroitin Sulphate Moiety in Type 1 and Type 2 Diabetes by Antonio Junior Lepedda, Gabriele Nieddu, Silvia Rocchiccioli, Nadia Ucciferri, Michela Idini, Pierina De Muro, Marilena Formato

    Published 2018-01-01
    “…Diabetes mellitus is a global health problem representing the fifth leading cause of mortality and a major risk factor for cardiovascular diseases. In the last years, we reported an association among urinary trypsin inhibitor (UTI), a small proteoglycan that plays pleiotropic roles in many inflammatory processes, and both type 1 and 2 diabetes and developed a method for its direct quantitation and structural characterization. …”
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  10. 2490

    Determinants of mortality after massive transfusion - A prospective study by Divya Venugopal, Susheela Jacob Innah, Aboobacker Mohamed Rafi, Ramesh Bhaskaran

    Published 2024-12-01
    “…Emergency admission was an independent risk factor for mortality. Hypotension before the initiation of MT was detrimental for survival. …”
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  11. 2491

    Improvement of Hypertension after Parathyroidectomy of Patients Suffering from Primary Hyperparathyroidism by P. D. Broulik, A. Brouliková, S. Adámek, P. Libanský, J. Tvrdoň, K. Broulikova, J. Kubinyi

    Published 2011-01-01
    “…PHPT is accompanied by a variety of metabolic complications, which are a risk factor for hypertension, and parathyroidectomy can improve these metabolic complications.…”
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  12. 2492

    Higher Levels of High-Sensitivity C-Reactive Protein Is Positively Associated with the Incidence of Hyperuricemia in Chinese Population: A Report from the China Health and Retireme... by Hui-Xu Dai, Zhi-Ying Zhao, Yang Xia, Qi-Jun Wu, Yu-Hong Zhao

    Published 2020-01-01
    “…The findings of this prospective cohort study suggest that higher level of high-sensitivity CRP is an independent risk factor for hyperuricemia in Chinese, especially in women.…”
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  13. 2493

    Familial Aggregation for Ischemic Heart Disease by José Leandro Pérez Guerrero, William Arias Salazar

    Published 2022-09-01
    “…Hyperlipidemia was the most frequent risk factor with 36.7 % in the case group and 37.1 % in the control group. …”
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  14. 2494

    The Interaction of lncRNA-HEIH and lncRNA-HULC with HBXIP in Hepatitis B Patients by Lingjuan Ruan, Lifei Huang, Lilai Zhao, Qiang Wang, Xiaocheng Pan, Anmin Zhang, Qiuping Bai, Zongjun Lv

    Published 2018-01-01
    “…Hepatitis B virus (HBV) infection is a major risk factor for the development of hepatic cirrhosis (HC) and hepatocellular carcinoma (HCC), which are associated with very high morbidity and mortality rates worldwide. …”
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  15. 2495

    Environmental noise exposure and autoimmune diseases: Evidence from a national cohort study by Seunghyun Lee, Yongho Lee, Wanhyung Lee, Xiaoxue Ma

    Published 2025-01-01
    “…This study provides evidence of a significant association between high environmental noise exposure and increased risk of autoimmune diseases, indicating noise as a modifiable risk factor.…”
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  16. 2496

    Text mining of hypertension researches in the west Asia region: a 12-year trend analysis by Mohammad Rezapour, Mohsen Yazdinejad, Faezeh Rajabi Kouchi, Masoomeh Habibi Baghi, Zahra Khorrami, Morteza Khavanin Zadeh, Elmira Pourbaghi, Hassan Rezapour

    Published 2024-12-01
    “…More than half of the world population lives in Asia and hypertension (HTN) is the most prevalent risk factor found in Asia. There are numerous articles published about HTN in Eastern Mediterranean Region (EMRO) and artificial intelligence (AI) methods can analyze articles and extract top trends in each country. …”
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  17. 2497

    Statins and the incidence of post-stroke depression: a systematic review and meta-analysis by Chaohua Cui, Jue Li, Weicong Chen

    Published 2025-01-01
    “…Brain inflammation is a risk factor for PSD. Statins might be beneficial due to their anti-inflammatory properties. …”
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  18. 2498

    Impact of coronavirus (COVID-19) pandemic on physical activity levels in different sub-populations of Iranians: a national survey by Hamid Arazi, Behzad Taati

    Published 2025-01-01
    “…A sedentary lifestyle is widely recognized as a significant risk factor for various diseases, necessitating extensive big data analysis to uncover the diverse aspects linked to the COVID-19 pandemic. …”
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  19. 2499

    Functional Role of miR-499a-5p in the Development of Gastric Cancer by Cuiling Lu, Chengwang Guo, Cuihua Wu, Liping Zhang, Xiaoling Liu, Shoucun Guo

    Published 2025-01-01
    “…Furthermore, miR499a-5p is also related to GC and 5-year survival, and is a risk factor for GC death. Conclusion: The levels of miR-499a-5p were markedly downregulated in GC and related to GC pathological features. …”
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  20. 2500

    Characterization of Chronic Mechanical Irritation in Oral Cancer by Jerónimo P. Lazos, Eduardo D. Piemonte, Hector Eduardo Lanfranchi, Mabel N. Brunotto

    Published 2017-01-01
    “…Oral mucosa could host many lesions originated by chronic mechanical irritation (CMI) from teeth or dentures, and it has been proposed as risk factor for oral cancer. Nevertheless, the features of CMI factors in oral cancer and other lesions are not assessed. …”
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