Early embryonic developmental toxicity of TPhP and CDP: Roles of PPARγ by Jing HUANG, Yunuo ZHAI, Boyang LI, Jing JI, Chuanhai LI, Shixin LIU, Yiman LIU, Junhua YUAN, Qixiao JIANG

“…It is necessary to elucidate these developmental toxicological effects and underlying mechanisms to improve risk assessments and better protect sensitive populations. …”
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Thrombolytic therapy for patients with acute ischemic stroke: systematic review and network meta-analysis of randomized trials by Li-Chao-Yue Sun, Wen-Shu Li, Wei Chen, Zhao Ren, Chun-Xing Li, Ze Jiang, Le Wang, De-Li Wang, Qing Xie

“…Data on study characteristics, patient demographics, interventions, and outcomes were extracted, and bias risk assessed. A multivariate random-effects model was used for network meta-analysis to derive odds ratios (OR) and 95% confidence intervals (CI).ResultTwelve RCTs were included (10 with tenecteplase, 2 with reteplase) involving 6,633 patients, all compared against 0.9 mg/kg alteplase. …”
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The burden of acute respiratory infection attributable to fine particulate matter brought by dust storms among children under 5 years of age in low- and middle-income countries by Hong Lu, Mingkun Tong, Ruohan Wang, Ning Kang, Xueqiu Ni, Jianyu Deng, Jiajianghui Li, Pengfei Li, Tianjia Guan, Tong Zhu, Tao Xue

“…However, the relationship used to evaluate the disease burden is mainly based on the total PM2.5 concentration, neglecting the specific effect of dust PM2.5 distinct from other PM2.5.This study aimed to develop a dust-specific exposure–response function (ERF) of ARI in children <5 years of age (U5-ARI) for future risk assessments. Method: We combined population data derived from the Demographic and Health Survey covering 53 LMICs, with environmental data, including the gridded concentration of dust PM2.5. …”
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Systematic review and meta-analysis to examine intrapartum interventions, and maternal and neonatal outcomes following immersion in water during labour and waterbirth by Priscilla J Hall, Claire Feeley, Ethel Burns, Jennifer Vanderlaan

“…Begg’s test and Egger’s regression risk assessed risk of bias across studies. Trim-and-fill analysis was used to estimate the magnitude of effect of the bias. …”
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