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Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans
Published 2025-01-01Get full text
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Polytene chromosomes reflect functional organization of the Drosophila genome
Published 2019-03-01Get full text
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Negative heterosis for meiotic recombination rate in spermatocytes of the domestic chicken Gallus gallus
Published 2021-10-01Get full text
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Effect of lethal yellow (AY) mutation and photoperiod alterations on mouse behavior
Published 2019-02-01Get full text
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<i>In silico</i> search for and analysis of R gene variation in primitive cultivated potato species
Published 2024-04-01Get full text
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Advancing Alzheimer’s Diagnosis: The Role of AI - A Review
Published 2025-01-01“…However, theories of neurodegeneration related to the deposition of pathological proteins in the brain and the imbalance between individual neurotransmitters have allowed the development of effective diagnostic methods - laboratory determination of specific biomarkers (tau protein, β-amyloid) and their marking using PET (Amyloid PET, Tau PET). …”
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Features of the course of post-COVID-19 primary and recurrent herpetic keratitis
Published 2024-12-01Get full text
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Occurrence and assessment of chronic pain fatigue and sleep disturbance in axial spondyloarthritis patients
Published 2025-12-01“…Fatigue and sleep disturbance induced by inflammatory pain affect the health-related quality of life.Objectives To determine the occurrence of chronic pain, fatigue, sleep disturbance in axSpA, and their influence on the health-related quality of life.Patients Forty patients with axSpA were diagnosed according to Spondyloarthritis International Society (ASAS) classification criteria. Patients with rheumatoid arthritis, cancer, liver disease, and severe sleep or psychiatric disorders were excluded.Methods Complete blood count, erythrocyte sedimentation rate, C-reactive protein (CRP), human leucocyticantigen-B27, plain x-ray, and magnetic resonance imaging of the sacroiliac joints were performed. …”
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Autoinflammation with arthritis and dyskeratosis an inflammasomopathy: Case report and review of literature
Published 2022-01-01“…Inherited disorders of the inflammasome pathway causes dysregulated inflammasome activation, which presents with inflammation and other clinical features linked to the defective protein. Eight mutations have been previously described in the NLRP1 inflammasome protein, causing different inflammatory skin disorders. …”
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Investigating novel Streptomyces bacteriophage endolysins as potential antimicrobial agents
Published 2025-01-01Get full text
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Bioinformatics and Deep Learning Approach to Discover Food-Derived Active Ingredients for Alzheimer’s Disease Therapy
Published 2025-01-01“…Random forest regression models were utilized to predict the IC<sub>50</sub> (pIC<sub>50</sub>) values of ligands interacting with AD-related target proteins, including acetylcholinesterase (<i>AChE</i>), amyloid precursor protein (<i>APP</i>), beta-secretase 1 (<i>BACE1</i>), microtubule-associated protein tau (<i>MAPT</i>), presenilin-1 (<i>PSEN1</i>), tumor necrosis factor (<i>TNF</i>)<i>-α</i>, and valosin-containing protein (<i>VCP</i>). …”
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