Targeted Next-Generation Sequencing in Pneumonia: Applications in the Detection of Responsible Pathogens, Antimicrobial Resistance, and Virulence by Liu B, Bao Z, Chen W, Xi X, Ge X, Zhou J, Zheng X, Zhang P, Deng W, Ding R, Zhou M, Fang J

“…We aimed to explore the applicability of tNGS in the co-detection of the responsible pathogens, antimicrobial resistance (AMR) genes, and virulence genes in patients with pneumonia.Methods: A prospective study was conducted among patients with suspected pneumonia at Ruijin Hospital from March 1 to May 31, 2023. …”
Get full text

Effect of Different Doses of Intrathecal Nalbuphine as Adjuvant to Hyperbaric Bupivacaine on Characteristics of Subarachnoid Block in Pelvic and Lower Limb Orthopaedic Surgeries: A... by Anupama Kumari, Shraddha Jogani, Nilesh Shah, Sara Mary Thomas

“…Materials and Methods: This prospective, double-blinded and randomised clinical study was conducted in the Department of Anaesthesiology, Shrimati Bhikhiben Kanjibhai Shah Medical Institute and Research Centre (a tertiary care institute), Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara, Gujarat, India, from September 2023 to July 2024, with a sample size of 40 patients. …”
Get full text

Hepatocellular carcinoma risk scores for non-viral liver disease: A systematic review and meta-analysis by Laura Burke, Alexander Hinkson, Vincent Haghnejad, Rebecca Jones, Richard Parker, Ian A. Rowe

“…Method: The study was prospectively registered with PROSPERO (ID: CRD42022370078) and reported in accordance with PRISMA guidelines. …”
Get full text

Investigation of the effect of intravitreal bevacizumab treatment on left heart function using speckle tracking echocardiography by Mehmet Şahinbaş, İdris Buğra Çerik, Duygu Yalınbaş Yeter

“…In our study, we aimed to investigate the effects of anti-VEGF agents on left heart functions after intravitreal injection using speckle tracking echocardiography. Methods: In this prospectively designed study, 44 patients who were going to start intravitreal anti-VEGF treatment were included in the study. …”
Get full text

Improving the adoption of a school-based nutrition program: findings from a collaborative network of randomised trials by Courtney Barnes, Rachel Sutherland, Lisa Janssen, Jannah Jones, Katie Robertson, Justine Gowland-Ella, Nicola Kerr, Aimee Mitchell, Karen Gillham, Alison L. Brown, Luke Wolfenden

“…Trial registration The trials were prospectively registered with Australia New Zealand Clinical Trials Register: ANZCTR, ACTRN12622000257763, Registered 11/2/2022, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?…”
Get full text

BCL-2 overexpression exosomes promote the proliferation and migration of mesenchymal stem cells in hypoxic environment for skin injury in rats by Ying Wang, Guang Li, Guofeng Li, Yutao Pan, Zhongmin Liu

“…The wound treated with MSCs‐BCL-2 promotes the compose of new blood vessels and granulation tissue in the wound, the redifferentiation of epithelial cells and the remodeling of collagen, which has a high therapeutic prospect for chronic wounds and skin regeneration.…”
Get full text

Development and Validation of a Cost-Effective Machine Learning Model for Screening Potential Rheumatoid Arthritis in Primary Healthcare Clinics by Wu W, Hu X, Yan L, Li Z, Li B, Chen X, Lin Z, Zeng H, Li C, Mo Y, Wu Y, Wang Q

“…Our findings contribute positively and are poised to elevate prospective RA management, fostering improvements in healthcare sector responsiveness and resource efficiency.Keywords: rheumatoid arthritis, machine learning, primary health care…”
Get full text

Phenotypes of primary sclerosing cholangitis in children by M.B. Dyba, V.S. Berezenko

“…Materials and methods. Retrospective and prospective analysis of the clinical course of primary sclerosing cholangitis in children and adolescents who were treated and followed at the Department of Pediatric Hepatology from 2016 to 2024 was conducted. …”
Get full text

Prediksi Kelulusan Tepat Waktu Berdasarkan Riwayat Akademik Menggunakan Metode K-Nearest Neighbor by Imam Riadi, Rusydi Umar, Rio Anggara

“…Abstract Graduating on time is a plenary achievement to be achieved by all students or prospective students. Graduation has 2 classifications such as graduating not on time and graduating on time. …”
Get full text

Usefulness of a personalized algorithm‐based discharge checklist in patients hospitalized for acute heart failure by Florent Allain, Virginie Loizeau, Laure Chaufourier, Maya Hallouche, Laurence Herrou, Amir Hodzic, Katrien Blanchart, Annette Belin, Alain Manrique, Paul Milliez, Rémi Sabatier, Damien Legallois

“…Methods and results We designed an algorithm to generate PCL, based on 2016 HF European Society of Cardiology Guidelines and the screening of common comorbidities in elderly HF patients. We prospectively included 139 patients hospitalized for HF from May 2018 to October 2018. …”
Get full text

Diagnosis of Columnar Metaplasia of the Esophageal Mucosa in Patients with Complicated Gastroesophageal Reflux Disease by E. D. Fedorov, A. V. Shidii-Zakrua, L. M. Mikhaleva, K. S. Maslenkina, A. A. Lindenberg, D. E. Seleznev, V. O. Kaybysheva, T. A. Partenadze

“…Overall, 131 patients aged 18 to 84 years (mean age — 55.8 ± 16.7 years) with confirmed diagnosis of GERD complicated by development of metaplasia of mucosa of distal esophagus were included in retroand prospective study. At the prehospital stage the patients' complaints were estimated, anamnesis was taken. …”
Get full text

Effectiveness of late and very late antivenom administration on recovery from snakebite-induced coagulopathy in French Guiana: a population-based studyResearch in context by Jean Marc Pujo, Stephanie Houcke, Guy Roger Lontsi Ngoulla, Vivian Laurent, Boubacar Signaté, Rémi Mutricy, Alexis Frémery, Flaubert Nkontcho, Ibtissem Ben Amara, José María Gutiérrez, Dabor Resiere, Hatem Kallel

“…The secondary endpoint was to investigate the time needed from AV administration to recovery from SB-induced coagulopathy in patients receiving AV (late or very late administration). Methods: This prospective observational study was conducted in the Intensive Care Unit (ICU) of Cayenne General Hospital between January 2016 and September 2023. …”
Get full text

Comparison of Hyperbaric 0.5% Levobupivacaine and Hyperbaric 0.75% Ropivacaine for Intrathecal Use in Infraumbilical Surgeries: A Randomised Clinical Study by Tejash H Sharma, Jagrati Jain, Priya Kishnani, Richa Tailor, Sara Mary Thomas

“…Materials and Methods: This prospective, double-blinded and randomised clinical study was conducted in the Department of Anaesthesiology, Shrimati Bhikhiben Kanjibhai Shah Medical Institute and Research Centre (a tertiary care institute), Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara, Gujarat, India, from September 2023 to July 2024, with a sample size of 40 patients. …”
Get full text

Clinical features and predictors of atrial fibrillation in patients with light‐chain or transthyretin cardiac amyloidosis by Maria Papathanasiou, Aiste‐Monika Jakstaite, Sara Oubari, Johannes Siebermair, Reza Wakili, Julia Hoffmann, Alexander Carpinteiro, Tim Hagenacker, Andreas Thimm, Christoph Rischpler, Lukas Kessler, Tienush Rassaf, Peter Luedike

“…ATTR type of amyloidosis is the strongest predictor of AF. Prospective screening for occult AF may be considered in ATTR‐CA.…”
Get full text

National monitoring of antibiotic resistance of pathogens causing community-acquired urinary tract infections in Russia: results of the multicenter epidemiological study «DARMIS -2... by Kozlov R.S., Palagin I.S., Ivanchik N.V., Trushin I.V., Dekhnich A.V., Edelstein M.V., Perepanova T.S., Belashova M.A., Nastausheva T.L., Ivanova I.A., Valiullina I.R., Momotova A.A., Shirokova T.M., Kotov S.V., Pul'bere S.A., Petrova L.V., Eremeeva A.V., Popov S.V., Zhukov V.A., Suhorukova M.V., Plugin P.S., Nikitina I.V., Vityazeva V.P., Zlobnaya K.A., Ibishev H.S., Naboka Yu.L., Kuz'min I.V., Petrov S.B., Slesarevskaya M.N., Savicheva A.M., Husnutdinova T.A., Moskvitina E.N., Andronova T.I., Dolzhenko E.V., Sholomova L.A., Burasova E.G., Lupyreva E.G., Malyavin A.I., Sidorova R.K., Mihajlichenko A.O., Kataeva E.I., Shamaeva S.H., Ahremenko Ya.A., Portnyagina U.S., Ershova M.G.

“…Isolates were collected in 29 centers in 21 cities of Russia in 2023 as part of a multicenter prospective epidemiological study of the dynamics of antibiotic resistance of pathogens causing community-acquired UTIs in different subsets of patients ("DARMIS-2023"). …”
Get full text

Effects of 24 Weeks of Growth Hormone Treatment on Bone Microstructure and Volumetric Bone Density in Patients with Childhood-Onset Adult GH Deficiency by Hongbo Yang, Kemin Yan, Yuping Xu, Linjie Wang, Qi Zhang, Fengying Gong, Huijuan Zhu, Weibo Xia, Hui Pan

“…In this single-center prospective study, nine CO AGHD patients received rhGH treatment for 24 weeks. …”
Get full text

The HFA‐PEFF score identifies ‘early‐HFpEF’ phenogroups associated with distinct biomarker profiles by Michiel T.H.M. Henkens, Anne‐Mar vanOmmen, Sharon Remmelzwaal, Gideon B. Valstar, Ping Wang, Job A.J. Verdonschot, Mark R. Hazebroek, Leonard Hofstra, Vanessa P.M. vanEmpel, Joline W.J. Beulens, Hester M. denRuijter, Stephane R.B. Heymans

“…Methods and results Subjects referred to the Cardiology Centers of the Netherlands, location Utrecht, with non‐acute possibly cardiac‐related symptoms (such as dyspnoea or fatigue) were prospectively enrolled in the HELPFul cohort (N = 507) and were included in the current analysis. …”
Get full text

Ultra-fast [18F]florbetapir PET imaging using the uMI Panorama PET/CT system by Xueqian Yang, Meiqi Wu, Menglin Liang, Haiqiong Zhang, Bo Li, Chenhui Mao, Liling Dong, Yuan Wang, Haiqun Xing, Chao Ren, Zhenghai Huang, Qingxiang Wen, Qi Ge, Zhengqing Yu, Feng Feng, Jing Gao, Li Huo

“…Methods Thirty-eight participants (29 Aβ positive and 9 Aβ negative) from a prospective dementia cohort at Peking Union Medical University Hospital underwent routine [18F]florbetapir PET scans using the uMI Panorama PET/CT scanner and a T1-weighted brain MRI scan. …”
Get full text

Circulating Soluble ST2 Predicts All-Cause Mortality in Severe Heart Failure Patients with an Implantable Cardioverter Defibrillator by Zhi-wei Hou, Hai-bo Yu, Yan-chun Liang, Yang Gao, Guo-qing Xu, Min Wu, Zhu Mei, Zu-lu Wang, Zhi-guo Li, Yu-ying Li, Hai-xu Song, Jia-yin Li, Ya-ling Han

“…Between January 2017 and August 2018, we prospectively recruited consecutive patients implanted with an ICD for heart failure, with LVEF ≤35% as recommended, and analyzed the basic characteristics, baseline serum sST2, and NT-proBNP levels, with at least 1-year follow-up. …”
Get full text

Late gadolinium enhancement cardiovascular magnetic resonance with generative artificial intelligence by Omer Burak Demirel, Fahime Ghanbari, Christopher W. Hoeger, Connie W. Tsao, Adele Carty, Long H. Ngo, Patrick Pierce, Scott Johnson, Kathryn Arcand, Jordan Street, Jennifer Rodriguez, Tess E. Wallace, Kelvin Chow, Warren J. Manning, Reza Nezafat

“…The model was implemented inline, allowing the reconstruction of images on the scanner console. We prospectively enrolled 100 patients (55 ± 14 years, 72 males) referred for clinical CMR at 3T. …”
Get full text