Showing 1 - 20 results of 62 for search '"Pharmacogenetics"', query time: 0.05s Refine Results
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    Pharmacogenetics of Oral Antidiabetic Drugs by Matthijs L. Becker, Ewan R. Pearson, Ivan Tkáč

    Published 2013-01-01
    “…Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register studies, but only a handful of associations detected in these studies were replicated. …”
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    Pharmacogenetics of Risperidone and Cardiovascular Risk in Children and Adolescents by Amilton Dos Santos-Júnior, Taciane Barbosa Henriques, Maricilda Palandi de Mello, Osmar Henrique Della Torre, Lúcia Arisaka Paes, Adriana Perez Ferreira-Neto, Letícia Esposito Sewaybricker, Thiago Salum Fontana, Eloisa Helena Rubello Valler Celeri, Gil Guerra-Júnior, Paulo Dalgalarrondo

    Published 2016-01-01
    “…Although not higher than in the general pediatric population, a high frequency of patients was overweight/obese, with abnormalities in metabolic parameters and some pharmacogenetic associations.…”
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    Pharmacokinetic, Pharmacogenetic, and Other Factors Influencing CNS Penetration of Antiretrovirals by Jacinta Nwamaka Nwogu, Qing Ma, Chinedum Peace Babalola, Waheed Adeola Adedeji, Gene D. Morse, Babafemi Taiwo

    Published 2016-01-01
    “…Other factors are related to pharmacokinetics and pharmacogenetics of the specific ARV agent or mediated by drug interactions, local inflammation, and blood flow. …”
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    The Personalization of Clopidogrel Antiplatelet Therapy: The Role of Integrative Pharmacogenetics and Pharmacometabolomics by Arwa M. Amin, Lim Sheau Chin, Dzul Azri Mohamed Noor, Muhamad Ali SK Abdul Kader, Yuen Kah Hay, Baharudin Ibrahim

    Published 2017-01-01
    “…The advantage of pharmacometabolomics is that it does not only predict the response but also provide extensive information on the metabolic pathways implicated with the response. Integrating pharmacogenetics with pharmacometabolomics can give insight on unknown genetic and nongenetic factors associated with the response. …”
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    Optimizing Antipsychotic Therapy in Acute Alcoholic Hallucinosis through Pharmacogenetic Testing by Valentin Skryabin, Anton Masyakin, Sergei Pozdniakov, Igor Shatokhin, Svetlana Sokolova, Valentina Ivanchenko

    Published 2024-12-01
    “…The main group (n = 25) received treatment adjusted based on pharmacogenetic testing, while the control group (n = 25) received standard therapy with- out genetic data. …”
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    To be or not to be, when synthetic data meet clinical pharmacology: A focused study on pharmacogenetics by Jean‐Baptiste Woillard, Clément Benoist, Alexandre Destere, Marc Labriffe, Giulia Marchello, Julie Josse, Pierre Marquet

    Published 2025-01-01
    “…In this study, we implemented and compared three synthetic data generation methods, CT‐GAN, TVAE, and a simplified implementation of Avatar, for a previously published pharmacogenetic dataset of 253 patients with one measurement per patient (non‐longitudinal). …”
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    Assessing the Roles of Molecular Markers of Antimalarial Drug Resistance and the Host Pharmacogenetics in Drug-Resistant Malaria by Peter Hodoameda, Nancy Odurowah Duah-Quashie, Neils Ben Quashie

    Published 2022-01-01
    “…The parasite genetic factors involve undergoing mutation in the drug target sites or increasing the drug target gene copy number to prevent the intended action of the antimalarial drugs. The host pharmacogenetic factors which determine how a particular antimalarial drug is metabolized could result in variations of drug plasma concentration and consequently contribute to variable treatment outcomes and the emergence or propagation of resistant parasites. …”
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