Adherence to Viral Load Testing Guidelines, Barriers, and Associated Factors Among Persons Living with HIV on ART in Southwestern Uganda: a Mixed-Methods Study. by Lubega, Polly, Nalugya, Sylivia Juliet, Kimuli, Angella Namyalo, Twinokusiima, Majoreen, Khasalamwa, Mercy, Kyomugisa, Richard, Kabami, Jane, Owaraganise, Asiphas

“…Of the 395 patient charts reviewed, 317 had their VL testing (80.3%) per the guidelines (defined as up to one month post-due date). …”
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Assessing the Effects of Land Use Practices on the Environment in Rugarama North Ntungamo District. by Turyahabwe, Deus

“…Findings of the study indicates that there were effects of land use practices on environment as they include; Good quality yields indicated by 18%, Increased Quantity yield or yield per acre presented by 20%, improved soil fertility presented by 36% and other factors with 26%. …”
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Heart Rate in Hypertension: Review and Expert Opinion by Jamshed Dalal, Arup Dasbiswas, Immaneni Sathyamurthy, Srinivasa Rao Maddury, Prafulla Kerkar, Sandeep Bansal, Joy Thomas, Sankar Chandra Mandal, Soura Mookerjee, Sivakadaksham Natarajan, Viveka Kumar, Nishith Chandra, Aziz Khan, R. Vijayakumar, J. P. S. Sawhney

“…(iii) A reduced HR variability further adds to the propensity for the development of HTN, especially in men. (iv) Each 10 beats per minute increase in the resting HR can substantially increase the risk of adverse CV and mortality outcomes. …”
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Age, frequency, and strategy optimization for organized colorectal cancer screening: a decision analysis conducted in China for the years 2023–2038 by Zixing Wang, Wei Han, Ran Fei, Yaoda Hu, Fang Xue, Wentao Gu, Cuihong Yang, Yubing Shen, Luwen Zhang, Jingmei Jiang

“…Among these options, a risk-tailored scheme (standard colonoscopy every 5 years for high-risk and annual fecal immunochemical testing screening for moderate-to-low-risk) had a high probability (31.1%) of being optimal (with ≥ 40% uptake for a high-risk population, in particular), given China’s present per capita gross domestic product, and would yield the highest gain in quality-adjusted life years in 17 of 31 provinces. …”
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Incidence and risk factors for clinical omphalitis among neonates in Eastern Uganda using chlorhexidine gel for cord care: a community-cohort study by John Wogabaga, Kathy Burgoine, Abel Kakuru, Brendah Nambozo, Martin Chebet, Josephine Tumuhamye, Benon Wanume, Faith Oguttu, Milton W. Musaba, Agnes Napyo, Solomon Wani, Peter Olupot-Olupot, Andrew D. Weeks, Thorkild Tylleskär, David Mukunya

“…The incidence rate of omphalitis was 1.6 cases per 1000 person days (95% CI: 1.1, 2.3). Neonates born at home were twice as likely to develop omphalitis as those born in a health facility (adjusted hazards ratio (AHR) 1.99; 95% CI: 1.01, 3.9). …”
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Developing a clinical prediction model to modify empirical antibiotics for non-typhoidal Salmonella bloodstream infection in children under-five in the Democratic Republic of Congo by Bieke Tack, Daniel Vita, Jules Mbuyamba, Emmanuel Ntangu, Hornela Vuvu, Immaculée Kahindo, Japhet Ngina, Aimée Luyindula, Naomie Nama, Tito Mputu, Justin Im, Hyonjin Jeon, Florian Marks, Jaan Toelen, Octavie Lunguya, Jan Jacobs, Ben Van Calster

“…The net benefit for decisions thresholds < 30% ranged from 2.4 to 3.9 per 100 children. Conclusion The model predicts NTS bloodstream infection and can support the choice of empiric antibiotics to include coverage of drug-resistant NTS, in particular for decision thresholds < 30%. …”
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Efficacy and safety of surufatinib plus toripalimab in treatment-naive, PD-L1-positive, advanced or metastatic non-small-cell lung cancer and previously treated small-cell lung can... by Ying Cheng, Panpan Zhang, Ming Lu, Zhendong Chen, Lijie Song, Si Shi, Feng Ye, Xing Zhang, Baorui Liu, Dongmei Ji, Yanqiao Zhang, Weiguo Su, Michael Shi, Songhua Fan, Panfeng Tan, Chen Zhong

“…Primary endpoint was investigator-assessed objective response rate (ORR) per RECIST v1.1. Secondary endpoints included duration of response (DoR), disease control rate, progression-free survival (PFS), overall survival (OS), and safety. …”
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Efficacy and safety of guanabenz acetate treatment for non-alcoholic fatty liver disease: a study protocol for a randomised investigator-initiated phase IIa study by Atsushi Nakajima, Yasushi Honda, Kento Imajo, Masato Yoneda, Yuji Ogawa, Takaomi Kessoku, Takashi Kobayashi, Anna Ozaki, Asako Nogami, Satoru Saito, Michihiro Iwaki, Kosuke Tanaka, Atsushi Yamamoto, Kota Takahashi, Yuki Kasai, Noritoshi Kobayashi

“…Patients will be randomised to receive either 4 or 8 mg guanabenz acetate (n=14 per group). Blood tests and MRI will be performed 16 weeks after commencement of treatment. …”
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Prediction model study focusing on eHealth in the management of urinary incontinence: the Personalised Advantage Index as a decision-making aid by Huibert Burger, Henk van der Worp, Marco H Blanker, Marjolein Y Berger, Anne Martina Maria Loohuis, Nienke Wessels, Janny Dekker, Alec GGA Malmberg

“…Enrolment ended on July 2018.Participants Adult women were eligible if they had ≥2 episodes of UI per week, access to mobile apps and wanted treatment. …”
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Application of selection Index for enhancing resistance to Cryptocarya irritans and Vibrio alginolyticus in large yellow croaker by Jiaying Wang, Jiaying Wang, Ji Zhao, Ji Zhao, Bo Liu, Hongshu Chi, Pengxing Jiang, Pengxing Jiang, Junzu Xiao, Junzu Xiao, Zhou Jiang, Zhou Jiang, Lingwei Miao, Lingwei Miao, Qian He, Qian He, Junjia Zeng, Junjia Zeng, Qiaozhen Ke, Qiaozhen Ke, Tao Zhou, Tao Zhou, Peng Xu, Peng Xu

“…Despite the high cost of genotyping and the limited economic return per individual that restricts the use of genome selection technology in aquatic species breeding, integrating multiple traits in a selection index can reduce costs and present a promising direction for fish breeding. …”
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Effect of Du moxibustion in the treatment of Wind-phlegm disturbance vertigo (督灸疗法治疗眩晕风痰上扰证效果观察) by LUO Lihua (罗丽华), LI Silu (李思璐), LONG Yuqin (龙玉琴), YANG Yanni (杨燕妮), GENG Qingwen (耿庆文)

“…All patients received routine nursing during the treatment, and patients in the control group were given Du moxibustion therapy, 30 min per time, twice a week for 2 weeks. The degree of vertigo (posterior circulation ischemia) was measured before and after treatment. …”
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Application of a new highly multiplexed amplicon sequencing tool to evaluate Plasmodium falciparum antimalarial resistance and relatedness in individual and pooled samples from Dsc... by Jacob M. Sadler, Alfred Simkin, Valery P. K. Tchuenkam, Isabela Gerdes Gyuricza, Isabela Gerdes Gyuricza, Abebe A. Fola, Kevin Wamae, Ashenafi Assefa, Ashenafi Assefa, Karamoko Niaré, Kyaw Thwai, Samuel J. White, William J. Moss, Rhoel R. Dinglasan, Sandrine Eveline Nsango, Christopher B. Tume, Jonathan B. Parr, Jonathan B. Parr, Jonathan B. Parr, Innocent Mbulli Ali, Jeffrey A. Bailey, Jeffrey A. Bailey, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano

“…Control samples support that accurate genotyping as low as 1 parasite per microliter is routinely possible.…”
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How do leaf functional traits influence above-ground tree carbon in tropical hill forests of Bangladesh? by Ariful Khan, Md Rezaul Karim, Mohammed A.S. Arfin-Khan, Md. Shamim Reza Saimun, Fahmida Sultana, Sharif A. Mukul

“…The total carbon stock in RKWS was 1.98 % higher than in KNP per hectare, with species-specific carbon content varying across the landscape. …”
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Effects of functional diversity on ecosystem services in cocoa agroforestry systems in Costa Rica by Cassio Pinheiro Edelstein, Marney E. Isaac, Marney E. Isaac, Luis Orozco-Aguilar, Felipe Peguero, Felipe Peguero, Diego Delgado-Rodríguez, Rolando H. Cerda

“…Through the multiple regression analysis, we found that AFS dominated by species with greater maximum potential height, greater leaf nitrogen concentration, lower leaf dry matter content, lower leaf mass per area, and lower leaf nitrogen-phosphorus ratio were associated with higher carbon storage (R2 = 0.84), soil fertility (R2 = 0.7 for soil nitrogen), and multiple ecosystem services (R2 = 0.78). …”
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Daily feeding frequency impacts muscle characteristics and fat deposition in finishing pigs associated with alterations in microbiota composition and bile acid profile by Luga Hu, Huayu Tang, Zhaoxi Xie, Hongyu Yi, Lunjie Feng, Pan Zhou, Yong Zhang, Jingbo Liu, Xiang Ao, Jianchuan Zhou, Honglin Yan

“…Therefore, this study aimed to explore the effects of feeding frequency on muscle growth, fat deposition, cecal microbiota composition, and bile acid composition in finishing pigs.MethodsSixteen Sichuan-Tibetan black pigs, with an initial weight of 121.50 ± 1.60 kg, were divided into two groups and fed either two meals (M2) or four meals (M4) per day. The trial lasted 30 days. The muscle fiber characteristics, lipid metabolism in adipose tissue, and cecal microbiota and bile acid composition were determined.ResultsThe present study revealed that pigs fed four meals exhibited a lower feed-to-gain ratio, abdominal fat weight, and average backfat thickness (p &lt; 0.05), as well as a higher loin eye area (p = 0.09) and myofiber diameter in the longissimus muscle than their counterparts. …”
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Medication-related hospitalisations in patients with SLE by Arielle Mendel, Évelyne Vinet, Sasha Bernatsky, Christian A Pineau, Fares Kalache, Louis-Pierre Grenier, Emily G McDonald, Michèle Stanciu, Joo-Young Esther Lee, Gregory Clark

“…Age at SLE diagnosis&lt;18 years (OR 5.9, 95% CI 1.3 to 26.6) was associated with hospitalisation for a flare related to non-adherence.Conclusion Forty per cent of SLE hospitalisations were medication-related, while half were potentially preventable/ameliorable. …”
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Computational and in vitro evaluation of sumac-derived ©Rutan compounds towards Sars-CoV-2 Mpro inhibition by Muzaffar Kayumov, Parthiban Marimuthu, Parthiban Marimuthu, Jamoliddin Razzokov, Jamoliddin Razzokov, Jamoliddin Razzokov, Nurkhodja Mukhamedov, Nurkhodja Mukhamedov, Akmal Asrorov, Nodir S. Berdiev, Jamolitdin F. Ziyavitdinov, Ansor Yashinov, Ansor Yashinov, Yuliya Oshchepkova, Shavkat Salikhov, Sharafitdin Mirzaakhmedov

“…In silico results of R5 and R8 correspond with their in vitro outcomes. Furthermore, the per-residue decomposition analysis showed C145, E166, and Q189 residues as the hotspot residues for components contributing to maximum BFE energies. …”
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Efficacy of contralateral acupuncture in women with migraine without aura: protocol for a randomised controlled trial by Ling Zhao, Qifu Li, Yanan Wang, Jialei Feng, Xinghe Zhang, Siwen Zhao, Chonghui Xing, Yongli Song, Xuanxiang Zeng, Meng Kong, Yunqiu Zheng, Taipin Guo

“…Each group will be given 30-minute treatment sessions, once every other day, approximately three times per week, for a total of 24 treatments and follow-up visits two times. …”
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Automated method of bronchus and artery dimension measurement in an adult bronchiectasis population by Angelina L.P. Pieters, Qianting Lv, Jennifer J. Meerburg, Tjeerd van der Veer, Eleni-Rosalina Andrinopoulou, Pierluigi Ciet, James D. Chalmers, Michael R. Loebinger, Charles S. Haworth, J. Stuart Elborn, Harm A.W.M. Tiddens

“…The median (range) percentage of BA pairs defined as widened was 69 (55–84)% per CT using a cut-off value of 1.5 for Bout/A, and 53 (42–65)% of bronchial wall were thickened using a cut-off value of 0.14 for Bwt/A. …”
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<i>Sambucus nigra</i>-Lyophilized Fruit Extract Attenuated Acute Redox–Homeostatic Imbalance via Mutagenic and Oxidative Stress Modulation in Mice Model on Gentamicin-Induced Nephr... by Kamelia Petkova-Parlapanska, Ivaylo Stefanov, Julian Ananiev, Tsvetelin Georgiev, Petya Hadzhibozheva, Veselina Petrova-Tacheva, Nikolay Kaloyanov, Ekaterina Georgieva, Galina Nikolova, Yanka Karamalakova

“…Balb/c mice were divided into four (n = 6) groups: controls; <i>S. nigra</i> extract per os (120 mg kg⁻¹ day⁻¹ bw); GM (200 mg kg⁻¹ day⁻¹ bw) (4); and GM + <i>S. nigra</i> therapy. …”
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