Immunocytochemical and Morphometric Studies of Gastrin-, Somatostatin- and Serotonin-Producing Cells in the Stomach and Duodenum of Patients with Acid Peptic Disorders by WR Yacoub, ABR Thomson, P Hooper, LD Jewell

“…These results suggest that a change in the number of G, D or EC cells does not play a primary role in the pathophysiology of acid peptic disorders in the majority of patients.…”
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Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia by Anna Picca, Francesca Fanelli, Riccardo Calvani, Giuseppina Mulè, Vito Pesce, Alex Sisto, Cecilia Pantanelli, Roberto Bernabei, Francesco Landi, Emanuele Marzetti

“…Although muscle aging has been increasingly recognized as a biomarker of aging, the pathophysiology of sarcopenia is to date only partially appreciated. …”
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Placental Growth Factor, Soluble fms-Like Tyrosine Kinase 1, Soluble Endoglin, IL-6, and IL-16 as Biomarkers in Preeclampsia by Carmen Rădulescu, Anca Bacârea, Adina Huțanu, Rozalia Gabor, Minodora Dobreanu

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Effect of high-intensity interval training and moderate-intensity continuous training with quercetin supplementation on the mitochondrial gene expression in the diabetic heart by Mojdeh Khajehlandi, Lotfali Bolboli

“…It may contribute to the pathophysiology of diabetic cardiomyopathy and atherosclerosis. …”
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Risk Factors and Symptoms of Meibomian Gland Loss in a Healthy Population by Anna Machalińska, Aleksandra Zakrzewska, Krzysztof Safranow, Barbara Wiszniewska, Bogusław Machaliński

“…Our findings extend current knowledge on the pathophysiology of MGL.…”
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Recent advances in near-infrared photobiomodulation for the intervention of acquired brain injury by Yujing Huang, Yujing Zhang, Chen Yang, Mengze Xu, Zhen Yuan

“…In this review, we first inspected the possible physical and biological mechanisms of NIR-PBM, and then reported the pathophysiology and physiology of ABI underlying NIR-PBM intervention. …”
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Treatment of tardive dyskinesia caused by long-term antipsychotic use: case reports and literature review by I. Pabarčiūtė, M. Karnickas

“…In order to provide reliable evidence-based recommendations for the treatment of tardive dyskinesia and to better understand its pathophysiology, genetic predisposition, and therapeutic agents, more studies with larger samples and more uniform conditions are needed. …”
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The Microenvironmental Effect in the Progression, Metastasis, and Dormancy of Breast Cancer: A Model System within Bone Marrow by Bobby Y. Reddy, Philip K. Lim, Kimberly Silverio, Shyam A. Patel, Brian Wong Won, Pranela Rameshwar

“…The uncovered significance of the microenvironment in the pathophysiology of breast cancer metastasis has served to challenge previously widespread theories and introduce new perspectives for the future research to eradicate breast cancer. …”
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Role of HO/CO in the Control of Peripheral Circulation in Humans by David Sacerdoti, Despina Mania, Paola Pesce, Silvia Gaiani, Angelo Gatta, Massimo Bolognesi

“…Experimental studies show that the heme oxygenase/carbon monoxide system (HO/CO) plays an important role in the homeostasis of circulation and in the pathophysiology of hypertension. No data are available on its role in the control of peripheral circulation in humans. …”
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Intrauterine Fetal Surgery Current Approaches by Ayla Eser, Nermin Köşüş, Aydın Köşüş, Müberra Namlı Kalem, Nilüfer Akgün, Ebru Yüce

“…It is mainly indicated in diseases that can result in intrauterine fetal death or whose effects could not be corrected postnatally (congenital aortic valve stenosis, hypoplastic left heart syndrome ect.). The proven pathophysiology and proper identification of the defect or disease is thus necessary before attempting such intervention. …”
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Protein Kinase Cα Modulates Estrogen-Receptor-Dependent Transcription and Proliferation in Endometrial Cancer Cells by Alicia M. Thorne, Twila A. Jackson, Van C. Willis, Andrew P. Bradford

“…However, molecular mechanisms and signaling pathways underlying their etiology and pathophysiology remain poorly understood. We have shown that protein kinase Cα (PKCα) is aberrantly expressed in endometrioid tumors and is an important mediator of endometrial cancer cell survival, proliferation, and invasion. …”
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Toll-Like Receptor-4 Mediated Inflammation Is Involved in the Cardiometabolic Alterations Induced by Intermittent Hypoxia by Laureline Poulain, Vincent Richard, Patrick Lévy, Maurice Dematteis, Claire Arnaud

“…Intermittent hypoxia (IH) is a major component of sleep apnea syndrome as its cardiometabolic complications have been mainly attributed to IH. The pathophysiology is still poorly understood but there are some similarities with the obesity-associated cardiometabolic complications. …”
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Role of Mitogen-Activated Protein Kinase Pathways in Multifactorial Adverse Cardiac Remodeling Associated with Metabolic Syndrome by Mohamed Asrih, François Mach, Alessio Nencioni, Franco Dallegri, Alessandra Quercioli, Fabrizio Montecucco

“…This pathological remodeling has been described to result from the cardiac adaptive response to clinical mechanical conditions (such as hypertension, dyslipidemia, and hyperglycemia), soluble inflammatory molecules (such as cytokines and chemokines), as well as hormones (such as insulin), characterizing the pathophysiology of metabolic syndrome. Moreover, these cardiac processes (resulting in cardiac hypertrophy and fibrosis) are also associated with the modulation of intracellular signalling pathways within cardiomyocytes. …”
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Lymphocytic Esophagitis: Navigating an Uncharted Territory by Ahmad Jradi MD, Kaline Maya Khoury MD, Karam Karam MD, Dr. Ihab I. El Hajj MD, Elias Fiani MD

“…Studies are still limited in understanding the pathophysiology behind this disease warranting further research. …”
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Oxidative and Antioxidative Stress Status in Children with Inflammatory Bowel Disease as a Result of a Chronic Inflammatory Process by Urszula Grzybowska-Chlebowczyk, Paulina Wysocka-Wojakiewicz, Martyna Jasielska, Bożena Cukrowska, Sabina Więcek, Maria Kniażewska, Jerzy Chudek

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Frequent Sips of the Water for the Management of Gastroesophageal Reflux Induced Refractory Cough: A Case Report and Review of the Literature by Hassan Tariq, Jasbir Makker, Rafeeq Ahmed, Trupti Vakde, Harish Patel

“…Unresponsiveness warrants a thorough pulmonary evaluation. The pathophysiology of refractory cough in these patients is poorly understood, and hence management is often challenging. …”
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Quality of Life in Wilson’s Disease: A Systematic Literature Review by Chakrapani Balijepalli, Kevin Yan, Lakshmi Gullapalli, Stephane Barakat, Helene Chevrou-Severac, Eric Druyts

“…**Discussion:** Although our understanding of the underlying pathophysiology of WD has advanced, and novel therapeutics are on the horizon, our understanding of how WD affects overall QOL remains limited. …”
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The role of the corticotropin-releasing hormone and its receptors in the regulation of stress response by E. V. Sukhareva

“…In this review, attention will be paid to the role of CRH in the regulation of response to stress, as well as to the involvement of extrahypothalamic CRH in pathophysiology and the correction of mental disorders.…”
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Migraine and restless legs syndrome – is there an association? by D. Bučaitė, J. Normantas, G. Žemgulytė

“…Although the association between restless legs syndrome and migraine is being investigated, the predominant pathophysiological link has not yet been established. Separate treatment of these diseases has been known for a long time. …”
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Metagenomics Analysis of Microbial Species and Antibiotic Resistance Genes (ARGs) in Untreated Wastewater from Different Types of Hospitals in Hangzhou by Song Chen, Yi Zhou, Lu Song, Yanli Yang, Fuming He, Qianming Chen, Xi Cheng

“…A comprehensive understanding of the microbiological structure and the distribution of ARGs in hospital wastewater can facilitate appropriate treatment of such wastewater and can improve our understanding of the pathophysiology of several epidemic illnesses. In this work, metagenomics techniques were used to compare the microbial species and ARGs in a control group with those in untreated wastewater from three types of hospitals (a general hospital, a hospital of traditional Chinese medicine, and an oral specialty hospital). …”
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