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2401
Three Cases of Organized Hematoma of the Maxillary Sinus: Clinical Features and Immunohistological Studies for Vascular Endothelial Growth Factor and Vascular Endothelial Growth Fa...
Published 2015-01-01“…Furthermore, vascular endothelial growth factor and its receptor were expressed in the lesion. Conclusions. The pathogenesis of OH is unclear and it presents various histological and imaging findings; however, it is not difficult to rule out malignant tumors. …”
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2402
Systemic Candida parapsilosis Infection Model in Immunosuppressed ICR Mice and Assessing the Antifungal Efficiency of Fluconazole
Published 2015-01-01“…Data demonstrates that the research team has established a systemic C. parapsilosis infection model in immunosuppressed ICR mice, affording opportunities for increasing our understanding of fungal pathogenesis and treatment.…”
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2403
Iron Overload Impairs Bone Marrow Mesenchymal Stromal Cells from Higher-Risk MDS Patients by Regulating the ROS-Related Wnt/β-Catenin Pathway
Published 2020-01-01“…The higher incidence of ASXL1 and TET2 gene mutations in our iron overload (IO) MDS patients suggests that IO may be involved in the pathogenesis of MDS. The effects of IO damaging bone marrow mesenchymal stromal cells (MSCs) from higher-risk MDS patients were investigated. …”
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2404
Gut microbiome in non-alcoholic fatty liver disease
Published 2025-01-01“…The gut microbiome contributes to the pathogenesis of NAFLD through various pathways. Gut microbiota is at constant interactions with the intestinal epithelial barrier and affects its integrity. …”
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2405
Highly Expressing SCARA5 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma
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2406
Notch1 Signaling Regulates the Th17/Treg Immune Imbalance in Patients with Psoriasis Vulgaris
Published 2018-01-01“…Notch1 signaling may contribute to the pathogenesis of PV by regulating Th17/Treg immune imbalance.…”
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2407
Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling
Published 2013-01-01“…Abnormal angiogenesis and vascular remodeling contribute to pathogenesis of a number of disorders such as tumor, arthritis, atherosclerosis, restenosis, hypertension, and neurodegeneration. …”
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2408
CRISPR-Cas9 in basic and translational aspects of cancer therapy
Published 2024-11-01“…Conclusion: CRISPR-Cas9 system revolutionized the therapeutic strategies in some solid malignant tumors and leukemia through targeting the key genes involved in the pathogenesis of these cancers.…”
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2409
MicroRNA-155 Participates in the Expression of LSD1 and Proinflammatory Cytokines in Rheumatoid Synovial Cells
Published 2020-01-01“…Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 are key proinflammatory cytokines implicated in the pathogenesis of RA. In our study, we investigated whether miRNA-155 participates in the expression of LSD1 and proinflammatory cytokines in rheumatoid synovial cells. …”
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2410
Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysis
Published 2022-06-01“…However, the efficacy of laparoscopic left hemicolectomy remains unclear due to the differences in pathogenesis and surgical details between left and right colon cancers. …”
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2411
TNF-α and Microalbuminuria in Patients with Type 2 Diabetes Mellitus
Published 2014-01-01“…Recent evidence suggests that chronic subclinical inflammation plays a key role in the pathogenesis and progression of diabetic nephropathy. …”
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2412
Molecular Detection, Phylogenetic Analysis, and Identification of Transcription Motifs in Feline Leukemia Virus from Naturally Infected Cats in Malaysia
Published 2014-01-01“…Additionally, different enhancer motifs likely associated with FeLV related pathogenesis have been identified.…”
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2413
Characterization of Autoantibodies against the E1𝜶 Subunit of Branched-Chain 2-Oxoacid Dehydrogenase in Patients with Primary Biliary Cirrhosis
Published 2012-01-01“…These findings suggest that the E1𝛼 subunit as part of the native BCOADC complex is an immunogen, and that determinant spreading is involved in the pathogenesis of AMA production.…”
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2414
Inhibition of STING-mediated type I IFN signaling by African swine fever virus DP71L
Published 2025-02-01“…Taken together, these results highlight the important role of DP71L with respect to inhibition of interferon responses and provide guidance for a better understanding of ASFV pathogenesis and the development of live attenuated ASFV vaccines.…”
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2415
Acquired hypothyroidism, iodine status and hearing impairment in adults: A pilot study.
Published 2025-01-01“…Despite this, knowledge of the pathogenesis, incidence and severity of hearing impairment remains greatly lacking. …”
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2416
Enhanced infectivity of bovine viral diarrhoea virus (BVDV) in arginase-producing bovine monocyte-derived macrophages
Published 2024-12-01“…Macrophages are important cells of the innate immunity that play a major role in Bovine Viral Diarrhoea Virus (BVDV) pathogenesis. Macrophages are not a homogenous population; they exist in different phenotypes, typically divided into two main categories: classically (pro-inflammatory) and alternatively activated (anti-inflammatory) or M1 and M2, respectively. …”
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2417
Application of ursodeoxycholic acid at non-alcoholic and alcohol-induced steatohepatitis
Published 2010-06-01“…Article presents pathogenic mechanisms of the most important lesions of the liver – alcoholic and non-alcoholic steatohepatitis in pathogenesis of which the leading part belongs to accumulation of fat in cells of the organ and enhancement of lipid peroxidation processes with development of necrosis of hepatic cells. …”
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2418
Midline Anterior Neck Inclusion Cyst in a Pediatric Patient: A Case Report and Literature Review with a Dermatologic Perspective
Published 2025-01-01“…Further research may clarify the pathogenesis and long-term outcomes of these rare lesions.…”
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2419
The Diagnostic Role of Serum Inflammatory and Soluble Proteins on Dementia Subtypes: Correlation with Cognitive and Functional Decline
Published 2007-01-01“…In the past years, the possible involvement of inflammation in the pathogenesis of dementia has been the subject of several investigations. …”
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2420
Cytokine Profile of Patients with Allergic Rhinitis Caused by Pollen, Mite, and Microbial Allergen Sensitization
Published 2017-01-01“…Thus, along with other clinical trials, the study performed would clarify some aspects of molecular pathogenesis of human allergic rhinitis.…”
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