Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis by Udari Eshani Perera, Louise Organ, Simon G. Royce, Chrishan S. Samuel, Habtamu B. Derseh, Sasika N. V. Dewage, Emmanuel Koumoundouros, Andrew Stent, Kenneth J. Snibson

“…The role of inflammation in the pathogenesis of IPF is not well understood. This study evaluated the histopathological and inflammatory components of bleomycin-induced pulmonary fibrosis in mouse and sheep models, in terms of their ability to translate to the human IPF. …”
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Prevalence and Possible Role of Candida Species in Patients with Psoriasis: A Systematic Review and Meta-Analysis by Aldona Pietrzak, Ewelina Grywalska, Mateusz Socha, Jacek Roliński, Kinga Franciszkiewicz-Pietrzak, Lidia Rudnicka, Marcin Rudzki, Dorota Krasowska

“…Although fungal colonization is implicated in the pathogenesis of psoriasis, its prevalence remains unclear. …”
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Optical Coherence Tomography Biomarkers of the Outer Blood—Retina Barrier in Patients with Diabetic Macular Oedema by Ioana Damian, Simona Delia Nicoara

“…Lately, the focus of research shifted towards the external retinal barrier with potential involvement in the pathogenesis of DMO. Objective. We aim to identify the OCT changes of the external blood-retinal barrier in patients with DMO and to define them as biomarkers with predictive value. …”
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GDF15-mediated enhancement of the Warburg effect sustains multiple myeloma growth via TGFβ signaling pathway by Wenjing Xue, Ying Li, Yanna Ma, Feng Zhang

“…Overall, our study provides insights into the molecular mechanisms underlying MM pathogenesis and highlights the potential of targeting GDF15-TGFβ signaling -glycolysis axis as a therapeutic approach for future therapeutic interventions in MM.…”
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Principles of carbon catabolite repression in the rice blast fungus: Tps1, Nmr1-3, and a MATE-family pump regulate glucose metabolism during infection. by Jessie Fernandez, Janet D Wright, David Hartline, Cristian F Quispe, Nandakumar Madayiputhiya, Richard A Wilson

“…Perturbing CCR in Δtps1 and MDT1 disruption strains thus results in physiological defects that impact pathogenesis, possibly through the early expression of cell wall-degrading enzymes. …”
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Endothelial Progenitors as Tools to Study Vascular Disease by Reinhold J. Medina, Christina L. O'Neill, T. Michelle O'Doherty, Sarah E. J. Wilson, Alan W. Stitt

“…The use of OECs for modelling vascular disease will contribute greatly to improving our understanding of endothelial pathogenesis, which will potentially lead to the discovery of novel therapeutic strategies for vascular diseases.…”
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Regulation of calcium homeostasis in endoplasmic reticulum–mitochondria crosstalk: implications for skeletal muscle atrophy by Xuexin Li, Xin Zhao, Zhengshan Qin, Jie Li, Bowen Sun, Li Liu

“…This review explores the complex relationship between the ER and mitochondria and how these organelles regulate calcium levels in skeletal muscle, aiming to provide valuable perspectives for future research on the pathogenesis of muscle diseases and the development of prevention strategies.…”
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Hyperparathyroidism in Patients with End-Stage Chronic Liver Disease (Clinical Observations) by A. A. Lavreniuk, A. N. Gorbacheva, E. E. Bibik, A. K. Eremkina, I. N. Tikhonov, N. G. Mokrysheva

“…Bone diseases such as osteoporosis and osteomalacia are quite common in chronic liver disease, especially in cirrhosis and cholestatic diseases; however, the pathogenesis of these disorders and their relationship with mineral metabolism remain poorly understood. …”
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Association between oxidative balance score and gallstone disease: a population-based study from NHANES by Mengmeng Zhang, Aiming Yang

“…BackgroundOxidative stress has been reported to participant in the pathogenesis of gallstones. Oxidative balance score (OBS) represents pro-oxidant and antioxidant exposures to diet and lifestyle, closely associated with multiple metabolic disorders. …”
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Aortoenteric Fistula as a Complication of Open Reconstruction and Endovascular Repair of Abdominal Aorta by Marek Tagowski, Hendryk Vieweg, Christian Wissgott, Reimer Andresen

“…Mechanical injury, infection, and adherence of a bowel segment to the aorta or aortic graft are major etiologic factors of AEF after open aortic repair. The pathogenesis of AEF formation after endovascular abdominal aortic repair is related to mechanical failure of the stent-graft, to stent graft infection, and to persistent pressurization of the aneurysmal sac. …”
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Vegetative status in patients with transient ischemic attack and stroke by N. V. Halinouskaya, S. V. Samsonau

“…The key difference between TIA and TS is a difference in the relationship between the humoral regulation of the activities of the ANS and the parasympathetic part activity at the 1st day, which determines specific features of pathogenesis of the transient ischemia. …”
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Bayesian analysis of the rate of spontaneous malignant mesothelioma among BAP1 mutant mice in the absence of asbestos exposure by Dahlia M. Nielsen, Mei Hsu, Michael Zapata, Giovanni Ciavarra, Leonel van Zyl

“…However, since the molecular pathogenesis of MM in mice accurately recapitulates that of human disease, this disconnect between functional and epidemiological studies can be overcome by using inbred mouse strains that harbor mutation(s) in genes involved in the disease. …”
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Anti-ribosomal P2: could it be a useful new criterion for patients with systemic lupus erythematosus? by Menna N. Hemdan, Tayseer Khedr, Samar H. Goma, Fatma Mohammed Helbawi Mohammed, Maha S. I. Abdelrahman

“…It is closely linked to the pathogenesis of neuropsychiatric lupus. Further studies are required to assess anti-ribosomal antibody subunits’ diagnostic and clinical value.…”
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Current perspectives for metabolomics and lipidomics in dyslipidemia of acne vulgaris: a mini review by Liang Wu, Sheng-Cai Zhu, Yang He, Yun-Xia Zhu, Xiao-Liang Ou-Yang, Deng Zhang, Chun-Ming Li

“…Using metabolomics and lipidomics approach, a broad range of structurally diverse lipid species were detected and important lipid biomarkers were identified that are vital to the pathogenesis of AV. In this review, we will describe the recent progress in dyslipidemia of AV using metabolomics and lipidomics advances. …”
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Discovery of Novel Leaf Rust Responsive microRNAs in Wheat and Prediction of Their Target Genes by Dhananjay Kumar, Dharmendra Singh, Pulkit Kanodia, Kumble Vinod Prabhu, Manish Kumar, Kunal Mukhopadhyay

“…The present study provides insight into potential miRNAs with probable roles in leaf rust pathogenesis and their target genes in wheat which establish a foundation for future studies.…”
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Airway basal stem cell therapy for lung diseases: an emerging regenerative medicine strategy by Xingren Liu, Xin Wang, Xue Wu, Shuhua Zhan, Yan Yang, Caiyu Jiang

“…Abstract Chronic pulmonary diseases pose a prominent health threat globally owing to their intricate pathogenesis and lack of effective reversal therapies. …”
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Lymphocyte levels in Crohn’s disease patients in clinical remission are significantly lower than those in healthy people by Asi He, Tulan Hu, Linzhen Li

“…Lymphocytes migration is involved in the pathogenesis of IBD. The purpose of this study was to evaluate whether there were differences in blood lymphocytes levels between IBD patients in clinical remission and healthy people. …”
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Identification of biomarkers associated with ferroptosis in macrophages infected with Mycobacterium abscessus using bioinformatic tools. by Jiahua Qian, Chenghua Lu, Kai Meng, Zhihong Xu, Honghao Xue, Weijie Yang

“…Recent studies indicate that ferroptosis may play a critical role in the pathogenesis of M. abscessus pulmonary disease. We obtained gene expression microarray data from the Gene Expression Omnibus database, focusing on THP-1-derived macrophages infected with M. abscessus and uninfected controls. …”
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Outer Membrane Vesicles Derived from Adherent-Invasive Escherichia coli Induce Inflammatory Response and Alter the Gene Expression of Junction-Associated Proteins in Human Intestin... by Bahareh Nadalian, Banafsheh Nadalian, Mohammad Reza Zali, Abbas Yadegar

“…However, further investigations are needed to elucidate the putative role of OMVs in the pathogenesis of AIEC and IBD.…”
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The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease by Zhenzhen Lu, Yifei Zhong, Wangyi Liu, Ling Xiang, Yueyi Deng

“…Although some achievements have been made in the exploration of the pathogenesis of DKD, the currently available clinical treatment methods are still not completely effective in preventing the progress of DKD to ESRD. …”
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