Plasma Markers of Oxidative Stress in Patients with Gestational Diabetes Mellitus in the Second and Third Trimester by Hongwei Li, Qian Yin, Ning Li, Zhenbo Ouyang, Mei Zhong

“…Oxidation status increased in GDM, especially protein oxidation, which may contribute to the pathogenesis of GDM.…”
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Effect of Alkaloids from Nelumbinis Plumula against Insulin Resistance of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice by Yong Xie, Yi Zhang, Zebin Guo, Hongliang Zeng, Baodong Zheng

“…The present results supported the view that the pathogenesis of NAFLD was complex with inflammation, together with increasing serum glucose and IR. …”
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The predictive effects of adiponectin and irisin hormones on diagnosis and clinical involvement of Sarcoidosis by Huseyin Kaya, Hasim Boyaci, Serap Argun Baris, Ilknur Basyigit, Ozgur Doga Ozsoy, Hale Maral Kir

“…Adipokines and myokines secreted from adipose and muscle tissue play a role in the pathogenesis or protection against many inflammatory and autoimmune diseases in which inflammation and immunity form the basis. …”
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Bioinformatics analysis of mitochondrial metabolism-related genes demonstrates their importance in renal cell carcinoma by Mohsen Ahmadi, Maryam Motallebinezhad, Pegah Mousavi, Amir Hossein Miladipour, Shamim Fooladgar, Soudeh Ghafouri-Fard, Seyed Amirhossein Fazeli

“…Conclusion The current study further proved the importance of mitochondrial metabolic pathways in the pathogenesis of ccRCC and provided a list of possible diagnostic markers and therapeutic targets from these pathways that can be used in ccRCC.…”
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Triterpenoids from Chios Mastiha Resin Against MASLD—A Molecular Docking Survey by Nataša Milošević, Maja Milanović, Milica Medić Stojanoska, Varomyalin Tipmanee, Ilias Smyrnioudis, George V. Dedoussis, Nataša Milić

“…Based on the modified Delphi process, NAFLD was redefined as metabolic dysfunction-associated steatotic liver disease (MASLD) to highlight the metabolic aspect of liver pathogenesis. Chios mastiha (<i>Pistacia lentiscus</i> var. …”
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Atherosclerosis and Rheumatoid Arthritis: More Than a Simple Association by Lorenzo Cavagna, Nicola Boffini, Giovanni Cagnotto, Flora Inverardi, Vittorio Grosso, Roberto Caporali

“…The proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-6, involved in the pathogenesis of RA, are also independently predictive of subsequent cardiovascular disease (CVD). …”
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Pain in Parkinson's Disease Associated with COMT Gene Polymorphisms by Wanjun Li, Yongqian Chen, Bowen Yin, Limei Zhang

“…PD patients present high incidence of pain with unknown pathogenesis. Objective. We investigated the relation of COMT polymorphisms rs4633 and rs6267 with PD pain. …”
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Highly viable gastrointestinal Chlamydia trachomatis in women abstaining from receptive anal intercourse by Philip A. Karlsson, Mimmi Wänn, Helen Wang, Lars Falk, Björn Herrmann

“…Understanding CT dynamics in various infection sites can provide insights into the epidemiology and pathogenesis of CT.…”
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Effect of Baicalein on Cognitive Impairment in Diabetes Mellitus with Cerebral Small Vessel Disease by Li ZHOU, Zhengqi LU, Xiaoming YE, Wanxin YANG, Zhisheng WEI, Yi KONG, Xuming HUANG

“…Objective:To observe whether baicalein have therapeutic value on diabetes mellitus (DM) with cerebral small vessel disease (CSVD) so as to explore the pathogenesis and therapy of the cognitive ability and behavioral function disorder caused by chronic cerebral ischemia and hypoxia.Methods:A total of thirty male SD rats were randomly divided into normal control group, model group and treatment group, 10 rats in each group. …”
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Does the Gut Microbiota Influence Immunity and Inflammation in Multiple Sclerosis Pathophysiology? by Monika Adamczyk-Sowa, Aldona Medrek, Paulina Madej, Wirginia Michlicka, Pawel Dobrakowski

“…Gut microbiota may be of a great importance in the pathogenesis of MS, since recent findings suggest that substitutions of certain microbial population in the gut can lead to proinflammatory state, which can lead to MS in humans. …”
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The Association between Hypertension and Dementia in the Elderly by Michiya Igase, Katsuhiko Kohara, Tetsuro Miki

“…In connection to this, some studies have suggested that HT in old age correlates with the pathogenesis of dementia. Since HT is potentially reversible, a number of randomized trials have examined whether antihypertensive treatment may help in preventing dementia occurrence. …”
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Neuroinflammation and Oxidative Stress in Diabetic Neuropathy: Futuristic Strategies Based on These Targets by Reddemma Sandireddy, Veera Ganesh Yerra, Aparna Areti, Prashanth Komirishetty, Ashutosh Kumar

“…Several theories of etiologies surfaced down the lane, amongst which the oxidative stress mediated damage in neurons and surrounding glial cell has gained attention as one of the vital mechanisms in the pathogenesis of neuropathy. Mitochondria induced ROS and other oxidants are responsible for altering the balance between oxidants and innate antioxidant defence of the body. …”
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Suppressed Programmed Death 1 Expression on CD4+ and CD8+ T Cells in Psoriatic Patients by Joanna Bartosińska, Ewelina Zakrzewska, Dorota Raczkiewicz, Joanna Purkot, Anna Michalak-Stoma, Małgorzata Kowal, Dorota Krasowska, Grażyna Chodorowska, Krzysztof Giannopoulos

“…Decreased PD-1 expression on the T cells may be responsible for impaired negative regulation of immune response in psoriasis pathogenesis.…”
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Regulator of Calcineurin 1 in Periodontal Disease by Ulrike Peters, Eleni Solominidou, Yüksel Korkmaz, Stefan Rüttermann, Astrid Klocke, Thomas Frank Flemmig, Thomas Beikler

“…Nuclear factor of activated T-cells (NFAT) and NF-kB pathway associated processes are involved in the pathogenesis of various inflammatory disorders, for example, periodontal disease. …”
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Recent Advances in Vaginal Atresia: A Literature Review by Xijuan Lin, Jia Kang, Lan Zhu

“…In this context, this article systematically reviews the epidemiological characteristics of vaginal atresia and explores its etiology from multiple perspectives, including developmental processes, genetic factors, and environmental factors, emphasizing the importance of genetic susceptibility and environmental interactions in the pathogenesis of the condition. Building upon a summary of the clinical presentations, classification, and diagnostic methods of vaginal atresia, this article provides an overview of current treatment strategies for both partial vaginal atresia and complete vaginal atresia, discusses the psychological status of affected patients, and examines fertility outcomes and sexual function. …”
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Specific Activity of Lactate Dehydrogenase in Muscle and Liver Tissues of Rats Exposed to Intermittent Hypobaric Hypoxia by Syarifah Dewi, Adiba Nur Ashri Ramadhani, Khoiriyyah Amalia Az-zahra, Wardaya Wardaya

“…This finding could be implemented in individuals who experience intermittent hypoxia exposures or in various diseases with hypoxic conditions as their pathogenesis.…”
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Study on the mechanism of plant metabolites to intervene oxidative stress in diabetic retinopathy by Tianyao Gong, Dongmei Wang, Dongmei Wang, Jinyan Wang, Qun Huang, Haiyan Zhang, Chunmeng Liu, Xinglin Liu, Hejiang Ye

“…Oxidative stress is an important pathogenesis of diabetic retinopathy. Plant metabolites can be divided into two types: primary metabolites and secondary metabolites, secondary metabolites are the main active components and important sources for developing new drugs. …”
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Induced Pluripotent Stem Cells: Generation Strategy and Epigenetic Mystery behind Reprogramming by Pengfei Ji, Sasicha Manupipatpong, Nina Xie, Yujing Li

“…More importantly, the applications of iPSC in the development of disease models such as neurodegenerative disorders greatly enhance our understanding of the pathogenesis of such diseases and also facilitate the development of clinical therapeutic strategies using iPSC generated from patient somatic cells to avoid an immune rejection. …”
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A potential VEGF-driven hypothesis of calvarial centripetal proliferation in cerebral proliferative angiopathy by Shigeta Miyake, Timo Krings, Tze Phei Kee, Thierry A. G. M. Huisman

“…Herein, we investigated the presence of calvarial thickening in patients with CPA, and discuss its potential pathogenesis. This retrospective multicenter cohort study enrolled 16 CPA patients from our institutions. …”
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Combined Treatment with Zinc Aspartate and Intravenous Immunoglobulins (IVIGs) Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) by Diana Straubel, Anja Thielitz, Annegret Reinhold, Kurt Grüngreiff, Dirk Reinhold

“…., multiple sclerosis (MS), an inflammatory autoimmune disorder with a clear T cell-mediated immune pathogenesis. The trace element zinc is shown to play a regulatory role in the maintenance of immune functions. …”
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