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2081
Clinical Practice Guidelines of Mongolian Medicine in Rehabilitation for Cerebral Infarction
Published 2021-08-01“…The cerebral infarction is divided into five types in Mongolian medicine, such as Heyi, Xila, Badagan, Qisu and Xieriwusu type, and analyzes its pathogenesis, treatment, internal treatment and external treatment in detail. …”
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2082
Causal associations between circulating protein ratios and drug resistance in papillary thyroid cancer: a Mendelian randomization study
Published 2025-01-01“…Conclusion These findings highlight the relevance of CPLRs in the pathogenesis and drug resistance of PTC, providing insights into potential biomarkers and therapeutic targets. …”
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2083
Prevalence of the oral pathogen Filifactor alocis and its FtxA toxin related to clinical parameters and presence of Aggregatibacter actinomycetemcomitans
Published 2025-01-01“…This emphasizes that F. alocis and its ftxA are involved in the pathogenesis of periodontitis and may have ecological roles, with diagnostic and prognostic implications for the disease.…”
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2084
Exploring potential biomarkers for acute myocardial infarction by combining circadian rhythm gene expression and immune cell infiltration
Published 2025-02-01“…Recent studies have implicated circadian rhythm and immune infiltration in the pathogenesis of AMI. This study hypothesizes that analyzing the interplay between circadian rhythm-related gene expression and immune infiltration identify highly specific diagnostic biomarkers for AMI. …”
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2085
Response Gene to Complement 32 is associated with poor patient survival and an inflamed tumor-immune microenvironment in clear cell renal cell carcinoma
Published 2025-02-01“…It has been well established that tumor-infiltrating lymphocytes (TILs) play a critical role in the pathogenesis and progression of clear cell renal cell carcinoma (ccRCC). …”
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2086
Intrathecal Resiniferatoxin Modulates TRPV1 in DRG Neurons and Reduces TNF-Induced Pain-Related Behavior
Published 2017-01-01“…TRPV1 is known to play an important role in the pathogenesis of inflammatory and neuropathic pain states. …”
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2087
ABO blood grouping in Egyptian children with rotavirus gastroenteritis
Published 2017-09-01“…This could highlight an important risk factor, which could play a significant role for the pathogenesis of rotavirus gastroenteritis and severity as well. …”
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2088
Unmet needs in atopic dermatitis management: an expert consensus
Published 2022-07-01“…Although considerable advances have been made in understanding the pathogenesis and its treatment, there is still limited transfer of this knowledge into daily management. …”
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2089
Evaluation of Serum D-dimer Levels and the Disease Severity in Patients of Chronic Urticaria
Published 2025-01-01“…Besides autoimmunity, the coagulation pathway is also involved in the pathogenesis of chronic urticaria (CU). Previous studies showed that plasma D-dimer levels paralleled the severity of the disease. …”
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2090
Endothelial Progenitor Cells in Diabetic Microvascular Complications: Friends or Foes?
Published 2016-01-01“…However, antivascular endothelial growth factor (anti-VEGF) treatment is the main therapy for diabetic retinopathy and nephropathy, indicating the uncertain role of EPCs in the pathogenesis of diabetic microvascular disease. In this review, we first illustrate how hyperglycemia induces metabolic and epigenetic changes in EPCs, which exerts deleterious impact on their number and function. …”
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2091
Endoplasmic Reticulum Stress in Systemic Lupus Erythematosus and Lupus Nephritis: Potential Therapeutic Target
Published 2023-01-01“…Approximately one-third to two-thirds of the patients with SLE progress to lupus nephritis (LN). The pathogenesis of SLE and LN has not yet been fully elucidated, and effective treatment for both conditions is lacking. …”
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2092
BONE MARROW MICROENVIRONMENT INVOLVEMENT IN T-MN: FOCUS ON MESENCHYMAL STEM CELLS
Published 2023-08-01“…One of the known drivers involved in this field is the bone marrow microenvironment (BMM) and in particular bone marrow mesenchymal stem cells (BM-MSC) whose role in t-MN pathogenesis is the topic of this mini-review. BM-MSC, physiologically, support HSC maintenance, self-renewal, and differentiation, through hematopoietic–stromal interactions and production of cytokines. …”
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2093
The Microbiota Profile Analysis of Combined Periodontal-Endodontic Lesions Using 16S rRNA Next-Generation Sequencing
Published 2021-01-01“…This study offered insights into the pathogenesis of retrograde pulpitis.…”
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2094
Targeting Myeloid-Derived Suppressor Cells Is a Novel Strategy for Anti-Psoriasis Therapy
Published 2020-01-01“…However, the role of MDSCs in the pathogenesis of psoriasis remains unclear. Here, we confirmed that the accumulation of human MDSCs is remarkably increased in skin lesions of psoriasis patients by flow cytometry. …”
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2095
Transmembrane and Ubiquitin-Like Domain-Containing 1 Promotes Glioma Growth and Indicates Unfavorable Prognosis
Published 2023-01-01“…This study contributes valuable insights into the multifaceted role of TMUB1 in glioma pathogenesis and its potential as a diagnostic and therapeutic target.…”
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2096
Chlamydia pneumoniae-Mediated Inflammation in Atherosclerosis: A Meta-Analysis
Published 2015-01-01“…Therefore, we performed a meta-analysis to clarify whether C. pneumoniae may contribute to the pathogenesis of atherosclerosis by enhancing inflammation. 12 case-control, 6 cross-sectional, and 7 prospective studies with a total of 10,176 patients have been included in this meta-analysis. …”
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2097
In Vivo and Cadaver Studies of the Canalicular/Lacrimal Sac Mucosal Folds
Published 2016-01-01“…They may be involved in the drainage of tears or the pathogenesis of acute dacryocystitis or lacrimal sac mucocele.…”
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2098
Lipid Peroxidation-Mediated Inflammation Promotes Cell Apoptosis through Activation of NF-κB Pathway in Rheumatoid Arthritis Synovial Cells
Published 2015-01-01“…Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of multiple joints. The central pathogenesis of RA is the proliferation of synovial fibroblasts in response to inflammatory cytokines. …”
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2099
Expression of the JAK/STAT Signaling Pathway in Bullous Pemphigoid and Dermatitis Herpetiformis
Published 2017-01-01“…Irregular functioning of the cascade may contribute to pathogenesis of autoimmune diseases; however, there are no reports concerning autoimmune bullous diseases yet to be published. …”
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2100
High-Salt Enhances the Inflammatory Response by Retina Pigment Epithelium Cells following Lipopolysaccharide Stimulation
Published 2015-01-01“…High-salt has been shown to play a role in the pathogenesis of autoimmune disease. In this study, we investigated the effect of high-salt on the production of inflammatory mediators by ARPE-19 cells and the possible mechanisms involved. …”
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