Valproate Treatment in an ALS Patient Carrying a c.194G>A Spastin Mutation and SMN2 Homozygous Deletion by Lucio Tremolizzo, Gessica Sala, Elisa Conti, Virginia Rodriguez-Menendez, Antonella Fogli, Angela Michelucci, Paolo Simi, Silvana Penco, Christian Lunetta, Massimo Corbo, Carlo Ferrarese

“…The patient was started on valproic acid (VPA, 600 mg/die per os) considering the capacity of this drug of increasing survival motor neuron through an epigenetic mechanism. …”
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CFO-CR: Carrier Frequency Offset Methodology for High-Rate Common Randomness Generation by Prashanth Kumar Herooru Sheshagiri, Martin Reisslein, Juan A. Cabrera, Frank H. P. Fitzek

“…., a low rate of CR bits per second is sufficient. However, emerging semantic communication paradigms, e.g., identification via channels, require high CR rates. …”
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Understanding barriers to veterinary involvement in dairy calf health management by Kristen Y. Edwards, Angel Abuelo, Stephen J. LeBlanc, Trevor J. DeVries, Michael A. Steele, Joao H. C. Costa, David L. Renaud

“…Additionally, the odds of frequently reviewing records increased with the amount of time spent working with calves (OR: 10.2 per 10% increment, 95% CI: 10.0–10.5). Veterinarians highly satisfied with their knowledge of neonatal calf diarrhea (NCD) prevention were more likely to make recommendations based on records (OR: 11.6, 95% CI: 1.9–72.4). …”
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Usefulness of Magnetoinertial Wearable Devices in Neurorehabilitation of Children with Cerebral Palsy by Marco Iosa, Manuela de Sanctis, Aurora Summa, Elena Bergamini, Daniela Morelli, Giuseppe Vannozzi

“…After neurorehabilitation, this last parameter increased more in CPI (35%) than in CPB (6%, p=0.017 for the interaction group per time). The results of the questionnaires showed that therapists agreed with the usability (100% judged it as “easy to use”) and usefulness of the MIMU-based assessment in defining patient-oriented interventions (87%). …”
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Enhancement of Cognitive Benefits and Anti-Anxiety Effects of <i>Phytolacca americana</i> Fruits in a Zebrafish (<i>Danio rerio</i>) Model of Scopolamine-Induced Memory Impairment by Lucia-Florina Popovici, Ion Brinza, Florentina Gatea, Georgiana Ileana Badea, Emanuel Vamanu, Simona Oancea, Lucian Hritcu

“…Acute administration of PEC and PEU (0.1, 0.5, and 1 mg/L) was conducted for one hour per day. In silico analyses were performed to evaluate the pharmacokinetic characteristics of the phenolic compounds discerned in the two extracts, using platforms such as SwissAdme, Molinspiration, ProToX-III, AdmetLab 3.0, PKCSM, and PASS. …”
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Survival Status and Predictors of Mortality among Newborns Admitted with Neonatal Sepsis at Public Hospitals in Ethiopia by Samuel Dessu, Aklilu Habte, Tamirat Melis, Mesfin Gebremedhin

“…The incidence of mortality was 8.65 per 100 neonates admitted with neonatal sepsis. …”
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Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules by Stella Bernardi, Chiara Dobrinja, Bruno Fabris, Gabriele Bazzocchi, Nicoletta Sabato, Veronica Ulcigrai, Massimo Giacca, Enrica Barro, Nicolò De Manzini, Fulvio Stacul

“…RFA costed €1,661.50, surgery costed €4,556.30, and short-stay surgery costed €4,139.40 per patient. RFA, however, did not allow for any pathologic analysis of the nodules, which, in 6 patients who had undergone surgery (8%), revealed that the nodules harboured malignant cells. …”
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Multipath joint ablation strategy for focal atrial tachycardia originating from patent foramen ovale: a case report by Fuqiang Liu, Yifei Li, Song Yan, Lijun Liu, Kaiyu Zhou, Yimin Hua

“…A 12-lead electrocardiogram revealed a narrow QRS complex tachycardia with a rate of 157 beats per minute and a prolonged RP relationship. Echocardiography indicated a severely reduced ejection fraction of 22%. …”
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Cardiopulmonary Resuscitation in Interfacility Transport: An International Report Using the Ground Air Medical Quality in Transport (GAMUT) Database by Utpal S. Bhalala, Neeraj Srivastava, M. David Gothard, Michael T. Bigham

“…We determined the overall CPR rate and CPR rates for adult, pediatric, and neonatal transport programs. The rate of CPR per total transports was expressed as percentage, and then, Spearman’s rho nonparametric associations were determined between CPR and other quality metrics tracked in the GAMUT database. …”
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ONKOLOGINIŲ LIGŲ GYDYMO POVEIKIS GYVENIMO KOKYBEI, SUSIJUSIAI SU BURNOS SVEIKATA by Eimantė Bubelė

“…Moksliniu aspektu būtina tirti ligos eigą, rašyti mokslinius straipsnius.Vien per 2020 metus jų parašyta daugiau nei 53000. Po onkologinio gydymo pacientai dažnai išliekamuosius reiškinius jaučia dar ilgus metus, vienas iš pagrindinių – pablogėjusi burnos ertmės sveikata. …”
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Influence of Vermicompost and Biofertilizers on Yield and Economic Feasibility of Dragon Fruit by Ravi Pratap, V. K. Tripathi, A. K. Trivedi

“…The maximum number of fruits per pillar (12.64), estimated yield (6.50 t ha-1), cost of cultivation (` 131645.60 ha-1), gross return (` 520000.00 ha-1), net return (` 388354.40 ha-1) and benefit: cost ratio (3.95) were found with vermicompost (0.5 kg plant-1),  Azospirillium (50 g plant-1) and PSB (50 g plant-1) in the second year of planting which may increase in subsequent years due to increase the number of fruits and yield plant-1. …”
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Differentiating self-disclosure interventions from self-involving interventions based on the assessment of the short-term therapeutic effects: preliminary results by Fabio Monticelli, Chiara Massullo, Antonino Carcione, Lucia Tombolini, Flaminia Guerra, Marianna Liotti, Cecilia Monticelli, Elena Gasperini, Marianna Russo, Samanta Novaretto, Letizia La Vista, Paola Mallozzi, Claudio Imperatori, Chiara Del Brutto, Benedetto Farina

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Targeting Liver Biopsies For Optimal Biopsy Site In Diffused Liver Disease Using Real-Time Shear Wave Elastography: A Prospective, Single Center Study by Naushaba Malik, Shahbakht Aftab, Rida Noor, Noor Aftab, Rizwan, Rehan

“…The new technique (SWE) could distinguish between mild or no scarring and moderate/severe scarring with good accuracy (over 95%) if the stiffness measured by the sound waves was at least 1.92 meters per second (m/s). Conclusions: This study compared a new sound wave technique (SWE) to a traditional method (TE) for diagnosing liver scarring (fibrosis) in people with chronic liver disease.  …”
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An Innovation to Address the Anterior Pelvic Ring Disruptions by Ramesh Perumal, Harish Mahesan, Dheenadhayalan Jayaramaraju, Rajasekaran Shanmuganathan

“…Materials and methods: A total of 21 patients between 2015 and 2018 with disrupted pelvic ring injuries for which open reduction and 4.5 DCP fixation are included in the study and classified according to Young–Burgess. All are evaluated as per advanced trauma life support (ATLS) protocol, and appropriate X-rays and computed tomography (CT) scans are taken. …”
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VEGFR-2 Expression in Glioblastoma Multiforme Depends on Inflammatory Tumor Microenvironment by Jana Jaal, Marju Kase, Ave Minajeva, Mikk Saretok, Aidi Adamson, Jelizaveta Junninen, Tõnis Metsaots, Tõnu Jõgi, Madis Joonsalu, Markus Vardja, Toomas Asser

“…After immunohistochemistry, the tissue expression of ICAM-1 (optical density), the number of VEGFR-2 positive (VEGFR-2+) blood vessels (per microscopic field), and the endothelial staining intensity of VEGFR-2 (score 0–3) were determined. …”
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Self-sampling and self-testing for HIV at a commercial and community-based test provider in the Netherlands: user preferences and usability by I. J. M. Willemstein, O. Shobowale, A. M. Żakowicz, H. Bos, E. L. M. Op de Coul

“…In total, 133 users completed the survey; 89 (67%) via the commercial provider and 44 (33%) via the community-based provider. Response rates per provider were 2% and 26%, respectively. Users who bought their test at the commercial provider were more often Gay and Bisexual Men (GBM) (42%), 35 + years (43%), and born in the Netherlands (89%), compared to those recruited through the community-provider (respectively 27%, 25%, 14%). …”
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Functional Prediction of Hypothetical Proteins from and Validation of the Predicted Models by Using ROC Curve Analysis by Md. Amran Gazi, Sultan Mahmud, Shah Mohammad Fahim, Mohammad Golam Kibria, Parag Palit, Md. Rezaul Islam, Humaira Rashid, Subhasish Das, Mustafa Mahfuz, Tahmeed Ahmeed

“…With over 164 million reported cases per annum, shigellosis accounts for 1.1 million deaths each year. …”
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Enhanced vehicle routing for medical waste management via hybrid deep reinforcement learning and optimization algorithms by Norhan Khallaf, Osama Abd-El Rouf, Abeer D. Algarni, Mohy Hadhoud, Ahmed Kafafy

“…However, this improvement comes at the cost of a 9% increase in distance, reflecting the longer routes needed to serve more hospitals per trip. Despite this trade-off, the algorithm’s ability to minimize fleet size while fully utilizing vehicle capacity makes it the optimal choice in scenarios where these factors are critical. …”
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Real-World Health Care Outcomes and Costs Among Patients With Juvenile Idiopathic Arthritis in Spain by Jordi Antón, Estefania Moreno Ruzafa, Mireia Lopez Corbeto, Rosa Bou, Judith Sánchez Manubens, Sonia Carriquí Arenas, Joan Calzada Hernández, Violetta Bittermann, Carolina Estepa Guillén, Juan Mosquera Angarita, Lucía Rodríguez Díez, Estíbaliz Iglesias, Miguel Marti Masanet, Berta Lopez Montesinos, Maria I. González Fernández, Alfonso de Lossada, Carmen Peral, Mónica Valderrama, Noelia Llevat, María Montoro Álvarez, Immaculada Calvo Penadés

“…Direct annual cost (excluding treatments) was €3654.60 (€3899.00). Indirect JIA cost per family was €747.20 (€1452.80). **Conclusion:** JIA causes significant costs to the Spanish healthcare system and affected families. …”
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Enhancing Secure Medical Data Communication Through Integration of LSB and DCT for Robust Analysis in Image Steganography by Ramyashree, P. S. Venugopala, S. Raghavendra, Vijay S. Kubihal

“…After conducting an experiment, the DCT technique is the most suitable approach for secure communication of medical data with capacity of 2.03 bits per pixel (bpp). The overall analysis of proposed work significantly improves result in terms of the security and robustness under various attacks.…”
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