Glutathione-S-Transferase p1 Gene Promoter Methylation in Cell-Free DNA as a Diagnostic and Prognostic Tool for Prostate Cancer: A Systematic Review and Meta-Analysis by Jinghe Ye, Mao Wu, Long He, Peng Chen, Hongtao Liu, Hongwei Yang

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Mechanisms and Mediators of Inflammation: Potential Models for Skin Rejection and Targeted Therapy in Vascularized Composite Allotransplantation by Theresa Hautz, Dolores Wolfram, Johanna Grahammer, Ravi Starzl, Christoph Krapf, Johann Pratschke, W. P. Andrew Lee, Gerald Brandacher, Stefan Schneeberger

“…Blocking these molecules has not only shown success in the treatment of inflammatory dermatoses, but also prolonged graft survival in various models of solid organ transplantation. In addition to T cell recruitment, ectopic lymphoid structures within the allograft associated with chronic rejection in solid organ transplantation might contribute to the strong alloimmune response towards the skin. …”
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A Patient Presenting with Concurrent Testis Torsion and Epididymal Leiomyoma by E. Arpali, A. Tok

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Therapeutic efficacy and prognostic indicators in re-resection for recurrent hepatocellular carcinoma: Insights from a retrospective study by Qi Fan, MM, Pengcheng Wei, MM, Delin Ma, MD, Qian Cheng, MD, Jie Gao, MD, Jiye Zhu, MD, Zhao Li, MD

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Gender disparity in living organ donation: a qualitative analysis of experiences and perceptions of female donors in Pakistan by Muhammad Ishaq, Javeria Saleem, Ruhma Binte Shahzad, Mahrukh Iqbal, Abida Tehreem, Raja Sajjad Asghar, Aleena Touqeer, Gul Mehar Javaid Bukkhari

“…Objectives This study aims to explore and analyse the interplay of sociocultural, psychological and institutional factors, gender roles and power dynamics in shaping the decision-making processes and experiences of living kidney and liver donors in Punjab, specifically focusing on women.Design This study employed a qualitative approach, using in-depth interviews to delve into the narratives and experiences of living kidney and liver donors in Punjab.Setting Punjab Human Organ Transplantation Authority (PHOTA), Lahore, Punjab, Pakistan.Participants 17 participants registered at the PHOTA for kidney or liver donation.Results Interviews with living donors at PHOTA, Lahore, provided qualitative data, which was then systematically coded and analysed to identify recurring themes that explore the underlying social and cultural reasons for the observed gender disparity. …”
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Assessment of Disease Activity in Small Bowel Crohn’s Disease: Comparison between Endoscopy and Magnetic Resonance Enterography Using MRIA and Modified MRIA Score by Arnaldo Scardapane, Annalisa Ambrosi, Emanuela Salinaro, Maria Elisabetta Mancini, Mariabeatrice Principi, Alfredo Di Leo, Filomenamila Lorusso, Amato Antonio Stabile Ianora, Giuseppe Angelelli

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Identification of tacrolimus-related genes in familial combined hyperlipidemia and development of a diagnostic model using bioinformatics analysis by Yuan Xu, Hongfei He, Haiyang Li

“…Background: Clinical observations have revealed that patients undergoing organ transplantation administered tacrolimus often experience abnormal lipid metabolism with serious consequences. …”
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Laparoscopic Reversal of Hartmann’s Procedure: State of the Art 20 Years after the First Reported Case by Adriana Toro, Annalisa Ardiri, Maurizio Mannino, Antonio Politi, Andrea Di Stefano, Zia Aftab, Abdelrahman Abdelaal, Maria Concetta Arcerito, Andrea Cavallaro, Marco Cavallaro, Gaetano Bertino, Isidoro Di Carlo

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Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass by Reuben J. Arasaratnam, Alejandro Restrepo

“…Posttransplant lymphoproliferative disease is a serious complication following stem cell and solid organ transplantation. Early recognition of the disease is important in facilitating timely therapy and improving long-term outcomes. …”
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New Potential Weapons for Refractory Scleritis in the Era of Targeted Therapy by Claudia Fabiani, Jurgen Sota, Maite Sainz-de-la-Maza, Laura Pelegrín, Giacomo Emmi, Giuseppe Lopalco, Florenzo Iannone, Lorenzo Vannozzi, Silvana Guerriero, Maria Chiara Gelmi, Donato Rigante, Gian Marco Tosi, José Hernández-Rodríguez, Luca Cantarini

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Shift in the profile and prognostic implications in invasive fungal rhinosinusitis: experience of 10 years in a tertiary center by Raúl Mellidez-Acosta, Lidia Torres-García, Miguel Saro-Buendía, Natalia Jaramillo-Ángel, Javier Cabrera-Guijo, Catalina Bancalari-Díaz, Noelia Muñoz-Fernández, Lucas Fito-Martorell, Miguel Armengot-Carceller, Alfonso García-Piñero

“…Less fulminant courses have been evidenced, being oncohematotological disease and solid organ transplantation the main predisposing conditions, instead of poorly controlled diabetes. …”
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The Crosstalk between Myeloid Derived Suppressor Cells and Immune Cells: To Establish Immune Tolerance in Transplantation by Chao Zhang, Shuo Wang, Cheng Yang, Ruiming Rong

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Immunosuppressant-Associated Neurotoxicity Responding to Olanzapine by James A. Bourgeois, Ana Hategan

“…Immunosuppressants, particularly tacrolimus, can induce neurotoxicity in solid organ transplantation cases. A lower clinical threshold to switch from tacrolimus to another immunosuppressant agent has been a common approach to reverse this neurotoxicity. …”
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Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfu... by Qiao Tang, Jiatao Xie, Yifei Wang, Chong Dong, Chong Dong, Qian Sun

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Current Bioengineering Methods for Whole Kidney Regeneration by Shuichiro Yamanaka, Takashi Yokoo

“…Here, we review recent advances in the field of kidney regeneration, including (i) the directed differentiation of induced pluripotent stem cells/embryonic stem cells into kidney cells; (ii) blastocyst decomplementation; (iii) use of a decellularized cadaveric scaffold; (iv) embryonic organ transplantation; and (v) use of a nephrogenic niche for growing xenoembryos for de novo kidney regeneration from stem cells. …”
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Late and Chronic Antibody-Mediated Rejection: Main Barrier to Long Term Graft Survival by Qiquan Sun, Yang Yang

“…Antibody-mediated rejection (AMR) is an important cause of graft loss after organ transplantation. It is caused by anti-donor-specific antibodies especially anti-HLA antibodies. …”
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Role of Sentinel Lymph Node Biopsy in the Management of Merkel Cell Carcinoma by Eric P. Arruda, Kevin M. Higgins

“…Other etiological factors include immune suppression, organ transplantation, and polyoma virus infection. MCC has a propensity to spread to regional lymphatics with a high locoregional recurrence rate. …”
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Lymphocytes in Placental Tissues: Immune Regulation and Translational Possibilities for Immunotherapy by Tom Erkers, Arwen Stikvoort, Michael Uhlin

“…Increasing the understanding of immune modulation during pregnancy can give valuable insight into other established fields such as allogeneic hematopoietic stem cell transplantation and solid organ transplantation. In these settings, lymphocytes are key components that contribute to inflammation and rejection of either patient or donor tissues following transplantation. …”
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A Case of Continuous Negative Pressure Wound Therapy for Abdominal Infected Lymphocele after Kidney Transplantation by Marco Franchin, Matteo Tozzi, Gabriele Soldini, Gabriele Piffaretti

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Evaluation of T Cell Immunity against Human Cytomegalovirus: Impact on Patient Management and Risk Assessment of Vertical Transmission by Giulia Freer, Paola Quaranta, Mauro Pistello

“…However, on particular occasions, it may represent a serious risk, as active infection is associated with rejection and disease after solid organ transplantation or fetal transmission during pregnancy. …”
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