Viral nucleic acid load in the milk of lactating mothers with COVID-19 and the prognosis of infants by Mengkun Wang, Yifei Li, Jie Lei, Huiyi Jiang

Subjects: “…Novel coronavirus Omicron variant…”
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Factors Related to Nurses' Anxiety Regarding the Omicron Covid-19 Variant in Bangli Regency by I Made Agus Budi Wijaya

“… Introduction : The COVID-19 pandemic, especially the Omicron Variant, has had a broad impact on human life, especially on the economic and health aspects, including for nurses who work at the forefront and are prone to experiencing anxiety. …”
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Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor by Acharya Balkrishna, Rishabh Dev, Sandeep Kumar, Anurag Varshney

“…This increased binding affinity of the Omicron variant is responsible for its increased internalization and infectivity. …”
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The effects of deprivation, age, and regional differences in COVID-19 mortality from 2020 to 2022: a retrospective analysis of public provincial data by Anqi A. Chen, Elizabeth M. Renouf, Charmaine B. Dean, X. Joan Hu

“…In the last subperiod when most public health protections were released and the Omicron variant dominated, the least advantaged group might suffer higher COVID-19 mortality. …”
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COVID-19 Vaccination Status and Pregnancy Outcome during Third Wave by Madhusudan Dey, Shyamji Tiwari, Sunil Chawla, Pranjali Dhume, Abhijit Kumar, Priyanshi Chowdhary, Reshu Rawal

“…However, COVID-19 Vaccine efficacy was reduced for the Omicron variant whereas it was highly efficacious for the Delta variant. …”
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Computational Study of the Phytochemical Constituents from Uncaria tomentosa Stem Bark against SARS-CoV-2 Omicron Spike Protein by Oscar Herrera-Calderon, Abdulrahman M. Saleh, Andres F. Yepes-Perez, Nada H. Aljarba, Saad Alkahtani, Gaber El-Saber Batiha, Renan Dilton Hañari-Quispe, Haydee Chavez, Josefa Bertha Pari-Olarte, Eddie Loyola-Gonzales, José Santiago Almeida-Galindo, José Francisco Kong-Chirinos, Taoufiq Benali

“…The SARS-CoV-2 Omicron variant has spread rapidly and is considered the predominant variant in the world, and its main characteristic is related to evade immunity from natural infection or vaccines, due to its multiple mutations in the spike protein. …”
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Omicron Positivity in Air of Hospital Settings Gathered COVID-19 Patients, Vaccinated/Unvaccinated Populations by Zeynep Ece Kuloğlu, Zeynep Bengi Eren, Bedirhan Haykar, Cansel Vatansever, Tayfun Barlas, Mert Ahmet Kuskucu, Gülen Güney-Esken, Füsun Can

“…Abstract The Omicron variant spreads quicker than the earlier variants and can evade the immune response. …”
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Clinical outcomes of early remdesivir administration in hospitalized patients at high risk for severe COVID-19 during the Omicron wave by Yeon Ju La, Won Sup Oh, Changhyup Kim, Myoung-nam Lim, Yong Duk Jeon

“…However, the effect of early remdesivir administration on Omicron variants, which are known to have decreased severity, remains unclear. …”
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A Variant of Concern (VOC) Omicron: Characteristics, Transmissibility, and Impact on Vaccine Effectiveness by Angel Yun-Kuan Thye, Jodi Woan-Fei Law

“…However, as of October 2022, only the Omicron variant remains a VOC. As compared to the previous variants, although Omicron has the most extensive mutations but it appears to have lower severity and risk of hospitalization. …”
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Predictive Assessment of the Antiviral Properties of Imperata cylindrica against SARS-CoV-2 by Frank Eric Tatsing Foka, Hazel Tumelo Mufhandu

“…The omicron variant and its sublineages are highly contagious, and they still constitute a global source of concern despite vaccinations. …”
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High-frequency PCR-testing as a powerful approach for SARS-CoV-2 surveillance in the field of critical infrastructure: A longitudinal, retrospective study in a German tertiary care... by Bastian Fischer, Martin Farr, Jan Gummert, Cornelius Knabbe, Tanja Vollmer

“…For example, the omicron-variant led to high reinfection-rates as well as lower Ct-values. …”
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Preventing Severe COVID-19 with Tixagevimab-Cilgavimab in Hematological Patients Treated with Anti-CD20 Monoclonal Antibodies: An International Multicenter Study by Hovav Azuly, Tali Shafat, Daniel Grupel, Tzvika Porges, Ran Abuhasira, Ana Belkin, Ofir Deri, Yonatan Oster, Shadi Zahran, Ehud Horwitz, Netanel A. Horowitz, Hazim Khatib, Marjorie Vieira Batista, Anita Cassoli Cortez, Tal Brosh-Nissimov, Yafit Segman, Linor Ishay, Regev Cohen, Alaa Atamna, Amy Spallone, Roy F. Chemaly, Juan Carlos Ramos, Michal Chowers, Evgeny Rogozin, Noga Carmi Oren, Şiran Keske, Orit Wolfovitz Barchad, Lior Nesher, on behalf of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Respiratory Viruses (ESGREV)

“…We aimed to evaluate the effectiveness of tixagevimab-cilgavimab (T-C) prophylaxis in preventing severe COVID-19 in patients with hematologic malignancies (HM) treated with anti-CD20 therapy during the early Omicron variant phase of the pandemic. Methods The European Society of Clinical Microbiology and Infectious Diseases Study Group for Respiratory Viruses (ESGREV) conducted a multicenter retrospective cohort study involving 15 centers from 5 countries. …”
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Neutralizing antibody test supports booster strategy for young individuals after SARS-CoV-2 Omicron breakthrough by Yichuan Yao, Yunru Yang, Qiqin Wu, Mengyao Liu, Wei Bao, Qiutong Wang, Meijun Cheng, Yunuo Chen, Yiting Yu, Yuan Cai, Mei Zhang, Jingxue Yao, Hongliang He, Changjiang Jin, Changcheng Zheng, Tengchuan Jin, Dali Tong

“…Abstract Background The SARS-CoV-2 Omicron variant, since its initial detection, has rapidly spread across the globe, becoming the dominant strain. …”
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SARS-CoV-2 infections in pediatric and young adult recipients of chimeric antigen receptor T-cell therapy: an international registry report by Hongyan Liu, Colleen Callahan, Shannon L Maude, Kevin Owen McNerney, Rebecca M Richards, Paibel Aguayo-Hiraldo, Friso G Calkoen, Julie-An Talano, Amy Moskop, Adriana Balduzzi, Jennifer Krajewski, Hema Dave, Anant Vatsayan, Yimei Li, Kara Lynn Davis

“…Prior to the emergence of the Omicron variant, of 47 infections, 19 (40.4%) resulted in hospital admission and 7 (14.9%) required intensive care, while after the emergence of the Omicron variant, of 23 infections, only 1 (4.3%) required admission and the remaining 22 (95.7%) had asymptomatic or mild COVID-19. …”
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A Dynamic Model of Information-Vaccination-Disease That Accounts for Emerging Viral Variants: Model Development and a Case Study for COVID-19 in Iceland by Laijun Zhao, Mingmin Ying, Ying Qian, Lixin Zhou, Pingle Yang

“…To analyze these factors, we developed mean-field equations for system dynamics to model the complex system of vaccine information dissemination and vaccination, calculated the basic reproduction rate number, and used the Icelandic COVID-19 outbreak (Omicron variant) as a case study. We found that in the face of emerging variants, increasing vaccine efficacy is more effective than increasing vaccination rates. …”
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Contagious disease outbreaks: Distinguishing between constant and variable order using the SEIAR model by S.Sepehr Tabatabaei, Mohammadreza Dehghan

“…The approach is validated on the Delta and Omicron variants of the Coronavirus epidemic in Iran. The variable-order model achieves a Mean Absolute Percentage Error (MAPE) of 0.80 % for the Delta variant and 0.51 % for the Omicron variant, significantly outperforming the best constant-order models with MAPEs of 0.92 % and 1.32 %, respectively. …”
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Identification of G-quadruplex-forming Sequences in Nucleocapsid Gene of SARS-CoV-2 Variants of Concern: An In Silico Analysis by Saeedeh Ghazaey Zidanloo

“…The main difference was observed in the Delta variant, in which a PQS was deleted at position 630 of the gene, which is the top-ranked highly conserved G-quadruplex. The Omicron variant had this PQS back at position 621 as it had acquired several mutations. …”
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In Silico Study of Coumarins: Wedelolactone as a Potential Inhibitor of the Spike Protein of the SARS-CoV-2 Variants by Saurav Katuwal, Siddha Raj Upadhyaya, Rishab Marahatha, Asmita Shrestha, Bishnu P. Regmi, Karan Khadayat, Saroj Basnet, Ram Chandra Basnyat, Niranjan Parajuli

“…Molecular docking studies revealed 26 coumarins with better binding energies than the reference ligands, molnupiravir and ceftazidime, against the S-RBD of the omicron variant. The top 10 best-docked coumarins were further analyzed to understand their binding interactions against the spike proteins of other variants (wild-type, Alpha, Beta, Gamma, and Delta), and these studies also demonstrated decent binding energies. …”
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Update on Remdesivir in the Treatment of Novel Coronavirus Pneumonia by Huang Feng, K. Vijaya Lakshmi, Chin Tat Ng, Murthy Sasikumar, Masita Arip, Masriana Hassan, Voon Kin Chin, Mogana Rajagopal, Omotayo Fatokun, N. Parvathi, Malarvili Selvaraja

“…Remdesivir has maintained high inhibitory activity against all existing SARS-CoV-2 variants, including the Omicron variant. We systematically retrieved Web of Science, CNKI, PubMed, and Clinicaltrials.gov to gather information related to Remdesivir on COVID-19 treatment. …”
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Persistent Health and Cognitive Impairments up to Four Years Post-COVID-19 in Young Students: The Impact of Virus Variants and Vaccination Timing by Ashkan Latifi, Jaroslav Flegr

“…The data further indicate that the ancestral SARS-CoV-2 variant may have the most significant long-term impact, while the Omicron variant appears to have the least. Interestingly, the severity of the acute illness was not correlated with the variant of SARS-CoV-2. …”
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