Longer-term safety and efficacy of baricitinib for atopic dermatitis in pediatric patients 2 to <18 years old: a randomized clinical trial of extended treatment to 3.6 years by Andreas Wollenberg, Masanori Ikeda, Chia-Yu Chu, Lawrence F. Eichenfield, Marieke M. B. Seyger, Apurva Prakash, Robinette Angle, Danting Zhu, Marco Pontes, Amy S. Paller

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A Clinical Mentorship and Quality Improvement Program to Support Health Center Nurses Manage Type 2 Diabetes in Rural Rwanda by Aphrodis Ndayisaba, Emmanuel Harerimana, Ryan Borg, Ann C. Miller, Catherine M. Kirk, Katrina Hann, Lisa R. Hirschhorn, Anatole Manzi, Gedeon Ngoga, Symaque Dusabeyezu, Cadet Mutumbira, Tharcisse Mpunga, Patient Ngamije, Fulgence Nkikabahizi, Joel Mubiligi, Simon Pierre Niyonsenga, Charlotte Bavuma, Paul H. Park

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Incidence of Hyperlipidemia among Adults Initiating Antiretroviral Therapy in the HIV Outpatient Study (HOPS), USA, 2007–2021 by Jun Li, Selom Agbobli-Nuwoaty, Frank J. Palella, Richard M. Novak, Ellen Tedaldi, Cynthia Mayer, Jonathan D. Mahnken, Qingjiang Hou, Kimberly Carlson, Angela M. Thompson-Paul, Marcus D. Durham, Kate Buchacz

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Assessing the Experiences of Sexual and Gender Minority Applicants to Orthopaedic Surgery Residency by Douglas J. Weaver, MD, Tanios Dagher, BS, Ngoc Duong, MS, Sara Winfrey, MD, Alexander Koo, MD, Tessa Balach, MD, FAOA

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Nailfold Capillary Hemorrhages: Microvascular Risk Factors for Primary Open-Angle Glaucoma by Nicholas M. Pfahler, Jordan L. Barry, Indre E. Bielskus, Agni Kakouri, Michael C. Giovingo, Nicholas J. Volpe, Paul A. Knepper

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Proteomic signature of HIV-associated subclinical left atrial remodeling and incident heart failure by Tess E. Peterson, Virginia S. Hahn, Ruin Moaddel, Min Zhu, Sabina A. Haberlen, Frank J. Palella, Michael Plankey, Joel S. Bader, Joao A. C. Lima, Robert E. Gerszten, Jerome I. Rotter, Stephen S. Rich, Susan R. Heckbert, Gregory D. Kirk, Damani A. Piggott, Luigi Ferrucci, Joseph B. Margolick, Todd T. Brown, Katherine C. Wu, Wendy S. Post

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The feasibility of implementing a digital pregnancy and postpartum support program in the Midwestern United States and the association with maternal and infant health by Colleen J. Klein, Matthew Dalstrom, William F. Bond, Jeremy McGarvey, Melinda Cooling, Katelyn Zumpf, Lisa Pierce, Brad Stoecker, Jonathan A. Handler

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Defining the Need for Causal Inference to Understand the Impact of Social Determinants of Health: A Primer on Behalf of the Consortium for the Holistic Assessment of Risk in Transp... by Nrupen A. Bhavsar, PhD, Rachel E. Patzer, PhD, David J. Taber, PharmD, Katie Ross-Driscoll, PhD, Rhiannon Deierhoi Reed, PhD, Juan C. Caicedo-Ramirez, MD, Elisa J. Gordon, PhD, MPH, Roland A. Matsouaka, PhD, Ursula Rogers, BS, Wendy Webster, MBA, Andrew Adams, MD, PhD, Allan D. Kirk, MD, Lisa M. McElroy, MD

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A maturity model for Clinical Trials Management Ecosystem by Shruti Sehgal, E. Chris Pua, Svetlana Rojevsky, Michael J. Becich, Joshua Fehrmann, Boyd M. Knosp, Adam Wilcox, Jeffery C. Talbert, Catherine K. Craven, Justin Starren

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Categorising implementation determinants and strategies within the US HIV implementation literature: a systematic review protocol by Justin D Smith, Brian Mustanski, Virginia McKay, James Lorenz Merle, Dennis Li, Brennan Keiser, Alithia Zamantakis, Artur Queiroz, Carlos G Gallo, Juan A Villamar, Juan Pablo Zapata, Nanette Benbow

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Supporting teams with designing for dissemination and sustainability: the design, development, and usability of a digital interactive platform by Maura M. Kepper, Allison J. L’Hotta, Thembekile Shato, Bethany M. Kwan, Russell E. Glasgow, Douglas Luke, Andrea K. Graham, Ana A. Baumann, Ross C. Brownson, Brad Morse

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Elucidating epigenetic landscape of gastric premalignant lesions through genome‐wide mapping of 5‐hydroxymethylcytosines: A 12‐year median follow‐up study by Zhongguang Luo, Wenshuai Li, Wanwei Zheng, Yixiang Shi, Maolin Ye, Xiangyu Guo, Kaiyi Fu, Changsheng Yan, Bowen Wang, Bin Lv, Shaocong Mo, Hongyang Zhang, Jun Zhang, Chuan He, Feifei Luo, Wei Zhang, Jie Liu

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Pilot study of a comprehensive multidisciplinary inpatient-based approach to smoking cessation in patients with vascular disease by Tanner Kim, MD, Anand Brahmandam, MBBS, Dana Alameddine, MD, Rachel Forman, MD, Amin Hardik, MD, Lisa Fucito, PhD, Carlos Mena-Hurtado, MD, Raul Guzman, MD, Cassius Iyad Ochoa Chaar, MD, MS, MPH

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Implementation of the Lupus Low Disease Activity State in Pediatric Rheumatology Care: The Role of the Visual Analog Scale by Ekemini A. Ogbu, Anna Carmela P. Sagcal‐Gironella, B. Anne Eberhard, Jennifer M. Huggins, Marisa S. Klein‐Gitelman, Karen Onel, Chen Chen, Bin Huang, Hermine I. Brunner

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Evaluating the World Health Organization’s Hearts Model for Hypertension and Diabetes Management: A Pilot Implementation Study in Guatemala by Irmgardt Alicia Wellmann, Luis Fernando Ayala, Taryn M. Valley, Vilma Irazola, Mark D. Huffman, Michele Heisler, Peter Rohloff, Rocío Donis, Eduardo Palacios, Manuel Ramírez-Zea, David Flood

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Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy by Timothy J Abreo, Emma C Thompson, Anuraag Madabushi, Kristen L Park, Heun Soh, Nissi Varghese, Carlos G Vanoye, Kristen Springer, Jim Johnson, Scotty Sims, Zhigang Ji, Ana G Chavez, Miranda J Jankovic, Bereket Habte, Aamir R Zuberi, Cathleen M Lutz, Zhao Wang, Vaishnav Krishnan, Lisa Dudler, Stephanie Einsele-Scholz, Jeffrey L Noebels, Alfred L George, Atul Maheshwari, Anastasios Tzingounis, Edward C Cooper

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SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocolsResearch in context by Moreno Ursino, Guillermo Villacampa, Jan Rekowski, Munyaradzi Dimairo, Olga Solovyeva, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Thomas R. Jeffry Evans, Elizabeth Garrett-Mayer, Robert M. Golub, Christina Guo, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Adrian Mander, Lynley V. Marshall, James Matcham, Dhrusti Patel, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Mahtab Rouhifard, Lesley Seymour, Yoshiya Tanaka, Christopher J. Weir, Johann de Bono, Christina Yap

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CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

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Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS... by Ramakanth Kavuluru, Xuan Wang, Paul Avillach, Florence Bourgeois, Kee Yuan Ngiam, Gabriel A Brat, Isaac Kohane, Tianxi Cai, Yuk-Lam Ho, Yuan Luo, Harrison G Zhang, Kelly Cho, Vincent Benoit, Antoine Neuraz, Chuan Hong, Sehi L'Yi, Griffin Weber, Bryce W Q Tan, Alba Gutiérrez-Sacristán, Clara-Lea Bonzel, Nathan P Palmer, Alberto Malovini, Valentina Tibollo, Meghan R Hutch, Molei Liu, Riccardo Bellazzi, Luca Chiovato, Fernando J Sanz Vidorreta, Trang T Le, William Yuan, Bertrand Moal, Michele Morris, David A Hanauer, Sarah Maidlow, Kavishwar Wagholikar, Shawn Murphy, Hossein Estiri, Adeline Makoudjou, Patric Tippmann, Jeffery Klann, Robert W Follett, Nils Gehlenborg, Gilbert S Omenn, Zongqi Xia, Arianna Dagliati, Shyam Visweswaran, Lav P Patel, Danielle L Mowery, Emily R Schriver, Malarkodi Jebathilagam Samayamuthu, Sara Lozano-Zahonero, Daniela Zöller, Amelia L M Tan, Byorn W L Tan, John H Holmes, Petra Schubert, Brett K. Beaulieu-Jones, Miguel Pedrera-Jiménez, Noelia García-Barrio, Pablo Serrano-Balazote, Andrew South

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