Editorial: Prostate cancer research: tools, cancer cell types, molecular targets by Hung-Ming Lam, Alvin Y. Liu

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Distinct MicroRNA Subcellular Size and Expression Patterns in Human Cancer Cells by Beibei Chen, Bo Zhang, Huaxia Luo, Jiao Yuan, Geir Skogerbø, Runsheng Chen

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Long Noncoding RNAs in Metabolic Syndrome Related Disorders by Magdalena Losko, Jerzy Kotlinowski, Jolanta Jura

“…Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. …”
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Stem cell status and prognostic applications of cuproptosis-associated lncRNAs in acute myeloid leukemia by Zhuodong Chai, Zhongyue Yuan, Yifei Chen

“…Additionally, we developed a prognostic model—the cuproptosis-associated long noncoding RNA prognostic model (CRLPM)—y analyzing data from The Cancer Genome Atlas (TCGA). …”
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Identification of Differentially Expressed lncRNAs in a CpG ODN-Activated Macrophage by Ying Zheng, Xi Luo, Zailong Qin, Zhiguang Zhou

“…CpG DNA is an immune stimulator recognized by TLR9, subsequently inducing inflammatory responses in macrophages. Long noncoding RNA (lncRNA) is a novel class of noncoding RNA, whose length is more than 200 nt, but without protein-coding capacity. lncRNAs are involved in many physiological and pathological processes, including inflammatory responses. …”
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m6A-modified lncRNA GAS5 promotes M1-polarization of microglia in alcohol use disorder by Shuang Zhu, Peng Wang, Jian Hu

“…Long noncoding RNA (lncRNA) are essential for modulating the onset and progression of alcohol use disorder (AUD). …”
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Epigenetic Modulation on Tau Phosphorylation in Alzheimer’s Disease by Chao-Chao Yu, Tao Jiang, Ao-Fei Yang, Yan-Jun Du, Miao Wu, Li-Hong Kong

“…Epigenetic modifications, such as noncoding RNA regulation, DNA methylation, and histone modification, can directly or indirectly affect the regulation of tau phosphorylation, thereby participating in AD development and progression. …”
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Methylated RNA Immunoprecipitation Sequencing Reveals the m6A Landscape in Oral Squamous Cell Carcinoma by Xi Wang, Jie Wu, Leyu Zhang, Wei Zhao, Jiayin Deng

“…The m6A peaks are always distributed in the junction of the 3′-untranslated regions (3′-UTRs) and the coding sequences (CDS) of mRNAs, as well as the entire genome of long noncoding RNA (lncRNA). Furthermore, enrichment analysis showed that differentially methylated genes were significantly enriched in NF-kappa B signaling pathway, Hedgehog signaling pathway, etc. …”
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MicroRNAs in Cerebral Ischemia by Yang Wang, Yongting Wang, Guo-Yuan Yang

“…Current studies found that microRNAs (miRNAs or miRs) are also closely related to the pathological process of stroke. miRNAs are a group of short, noncoding RNA molecules playing important role in posttranscriptional regulation of gene expression and they have emerged as regulators of ischemic preconditioning and ischemic postconditioning. …”
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The Roles of circRNAs in Intervertebral Disc Degeneration: Inflammation, Extracellular Matrix Metabolism, and Apoptosis by Hao Li, Lijun Tian, Jianhua Li, Yongjin Li, Lilong Du, Zhenxin Huo, Baoshan Xu

“…Circular RNAs (circRNAs), as a kind of noncoding RNA (ncRNA), participate in the regulation of genetic transcription and translation and further affect the expression of inflammatory cytokine, metabolism of extracellular matrix (ECM), the proliferation and apoptosis of cells, etc. …”
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Long Noncoding RNAs-Related Diseases, Cancers, and Drugs by Jen-Yang Tang, Jin-Ching Lee, Yung-Ting Chang, Ming-Feng Hou, Hurng-Wern Huang, Chih-Chuang Liaw, Hsueh-Wei Chang

“…Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. …”
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The Challenges and Opportunities in the Clinical Application of Noncoding RNAs: The Road Map for miRNAs and piRNAs in Cancer Diagnostics and Prognostics by Preethi Krishnan, Sambasivarao Damaraju

“…We now understand that coding and noncoding RNA machinery work in concert to maintain overall homeostasis. …”
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miR-155: An Important Role in Inflammation Response by Jingyan Hu, Songli Huang, Xiaoli Liu, Yuan Zhang, Shengli Wei, Xiuhua Hu

“…MicroRNAs (miRNAs) are a class of small, mature, noncoding RNA that lead to posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in biological processes such as cell development, cell differentiation, cell proliferation, and cell apoptosis. …”
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MicroRNA in Diabetic Nephropathy: Renin Angiotensin, AGE/RAGE, and Oxidative Stress Pathway by Shinji Hagiwara, Aaron McClelland, Phillip Kantharidis

“…MicroRNAs (miRNA) are a novel class of small, noncoding RNA molecules that have gained the attention of many researchers in recent years due to their ability to posttranscriptionally regulate the expression of families of genes simultaneously. …”
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TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation by Agnieszka Loboda, Mateusz Sobczak, Alicja Jozkowicz, Jozef Dulak

“…Recent findings indicate the prominent role of microRNAs, small noncoding RNA molecules that inhibit gene expression through the posttranscriptional repression of their target mRNAs, in different pathologic conditions, including renal pathophysiology. miR-21 was also shown to play a dynamic role in inflammatory responses and in accelerating injury responses to promote organ failure and fibrosis. …”
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The Role of MicroRNAs in Cardiac Stem Cells by Nima Purvis, Andrew Bahn, Rajesh Katare

“…MicroRNAs (miRs) are small, noncoding RNA molecules that regulate gene expression at the posttranscriptional level. …”
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Graph-Based Analysis of RNA Secondary Structure Similarity Comparison by Lina Yang, Yang Liu, Xiaochun Hu, Patrick Wang, Xichun Li, Jun Wu

“…Then, the distance matrix is analyzed by clustering and visualized as a clustering tree. RNA virus and noncoding RNA datasets are applied to perform experiments and analyze the clustering tree. …”
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Small Molecule, Big Prospects: MicroRNA in Pregnancy and Its Complications by Meng Cai, Gopi K. Kolluru, Asif Ahmed

“…MicroRNAs are small, noncoding RNA molecules that regulate target gene expression in the posttranscriptional level. …”
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An Independent Prognostic Model Based on Ten Autophagy-Related Long Noncoding RNAs in Pancreatic Cancer Patients by Jiahui Tian, Chunyan Fu, Xuan Zeng, Xiaoxiao Fan, Yi Wu

“…This study aims to explore the feasibility of using an autophagy-related long noncoding RNA (lncRNA) signature for assessing PC patient survival. …”
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SP-1-activated LINC01016 overexpression promotes gastric cancer invasion and metastasis through inhibiting EIF4A3-mediated MMP9 mRNA decay by Ying Sun, Hui Zhang, Duan-bo Shi, Peng Gao

“…In the present study, we showed that the expression of the long intergenic noncoding RNA 01016 (LINC01016) is significantly higher in GC tissues with lymph node metastasis (LNM) than those without LNM. …”
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