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Protective effects of seed oil from Nicotiana tabacum L. On D-galactose induced liver and brain damages of mice by regulating PI3K/Akt/Nrf2 signaling pathway
Published 2025-01-01“…Western blotting results showed that NC89 and BS4 increased the ratios of p-PI3K/PI3K and p-Akt/Akt, as well as the protein expression of Nrf2, NQO1 and HO-1 in brain tissues. Therefore, the potential protective mechanism of NC89 and BS4 on the liver and brain may be related to the activation of the PI3K/Akt/Nrf2 pathway and the inhibition of inflammatory responses. …”
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麋鹿被毛微量元素、重金属含量及对环境污染的监测作用
Published 2024-02-01“…结果表明:除Re元素外,其余43种元素在麋鹿被毛中均被检出,统计分析表明Li、Be、Sc、V、Co、Ga、Rb、Ir、Mo、Cd、Cs、Ba、La、Ce、Pr、Nd、Sm、Eu、Gd、Tb、Dy、Ho、Er、Tm、Yb、Lu、Tl、Bi、Th、U、Nb、Ta、Zr和Hf 34种元素为麋鹿被毛的特征元素;与北京南海子麋鹿种群相比,浙江临安麋鹿种群被毛中的微量元素Sr、In、Sb、W、Bi、U和重金属元素Zn、Cu、Cr、Pb、Cd含量更少,其余32种元素含量均高于北京南海子麋鹿种群;独立样本<italic>t</italic>检验分析表明,麋鹿被毛微量元素和重金属元素含量存在地域差异性,仅Cr(<italic>p</italic>=0.064)、Ni(<italic>p</italic>=0.769)、Mo(<italic>p</italic>=0.129)、Tl(<italic>p</italic>=0.065)、Zr(<italic>p</italic>=0.138)和Hf(<italic>p</italic>=0.057)6种元素差异不显著,其余37种元素差异均显著;北京南海子和浙江临安麋鹿种群的栖息环境和食物均未受到Zn、Cu、Cr、Pb、Cd、V、Co、Ni、Sb和Tl 10种重金属元素污染的威胁。…”
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Unconventional Hexagonal Close‐Packed High‐Entropy Alloy Surfaces Synergistically Accelerate Alkaline Hydrogen Evolution
Published 2025-01-01“…Abstract Accelerating the alkaline hydrogen evolution reaction (HER), which involves the slow cleavage of HO‐H bonds and the adsorption/desorption of hydrogen (H*) and hydroxyl (OH*) intermediates, requires developing catalysts with optimal binding strengths for these intermediates. …”
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Foreword
Published 2025-02-01“…The cultural aspect of Korean linguistics is explored through Eva VUČKOVIČ’s “Workplace Discourse and Expression of Hierarchy in Yoon Tae-ho’s Webtoon Misaeng,” which uses critical discourse analysis to examine hierarchical dynamics in corporate settings, as depicted in this iconic Korean webtoon. …”
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Resveratrol enhances post-injury muscle regeneration by regulating antioxidant and mitochondrial biogenesis
Published 2025-01-01“…Furthermore, RES enhanced antioxidant capacity via the Kelch-like ECH-associated protein 1 (KEAP-1)/nuclear factor erythroid 2-related factor 2 (NRF2)/heme oxygenase-1 (HO-1) signaling pathway, as indicated by elevated activities of total antioxidant capacity, Glutathione peroxidase (GSH-PX), and superoxidase dismutase (SOD). …”
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3,5,6,7,8,3’,4’- Heptamethoxyflavonoid inhibits TGF-β1-induced epithelial–mesenchymal transition by regulating oxidative stress and autophagy through MEK/ERK/PI3K/AKT/mTOR signalin...
Published 2025-02-01“…Various experiments confirmed that HMF regulated the expression levels of Nrf2, keap-1, HO-1, ROS, MDA, SOD, GSH, and played a role in reducing oxidative stress. …”
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Lutein and inflammation: a comprehensive review of its mechanisms of action
Published 2025-01-01“…Lutein protects against alcohol-induced liver damage by modulating the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway. Additionally, lutein promotes bone health by enhancing mineralized bone nodule development and inhibiting osteoclast production, reducing bone resorption, and suppressing soluble receptor activator of nuclear factor kappa B ligand (RANKL). …”
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Predictive models and determinants of mortality among T2DM patients in a tertiary hospital in Ghana, how do machine learning techniques perform?
Published 2025-01-01“…While previous research in the Ho municipality has primarily examined risk factors, comorbidity, and quality of life of T2DM patients, this study specifically investigated mortality predictors among these patients. …”
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Lactiplantibacillus plantarum AR113 alleviates microbiota dysbiosis of tongue coating and cerebral ischemia/reperfusion injury in rat
Published 2024-07-01“…Moreover, the gene expression of antioxidant-related proteins and apoptosis-related factors heme oxygenase-1 (HO-1), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), nuclear factor erythroid 2-related factor 2 (Nrf2), NAD(P)H:quinone oxidoreductase-1 (NQO-1), and Bcl-2 was significantly increased, but cytochrome C, cleaved caspase-3, and Bax were markedly decreased in the brain by AR113 treatment. …”
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Effects of dietary dihydroartemisinin on growth performance, meat quality, and antioxidant capacity in broiler chickens
Published 2025-01-01“…Compared to the control group, dihydroartemisinin at 10 and 20 mg/kg quadratically induced the hepatic mRNA expression of HO-1. Dihydroartemisinin at 10–40 mg/kg linearly and quadratically increased the mRNA expression of CAT in liver. …”
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The Northern and Southern Hemispheric Asymmetries of Mesospheric Ozone at High Latitudes During the January 2012 Solar Proton Events
Published 2023-05-01“…WACCM‐X simulations showed NOx (N, NO, and NO2) increased over 600% in both the northern and southern high latitudes during SPEs, while HOx (H, OH, and HO2) increased over 300% in the NH high latitudes and only over 30% in the SH high latitudes. …”
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Antihypertensive drug-related problems in Vietnamese ambulatory care
Published 2025-01-01Get full text
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Adsorption Ability for Toxic Chromium (VI) Ions in Aqueous Solution of Some Modified Oyster Shell Types
Published 2020-01-01Get full text
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Evaluating the impact of roof rainwater harvesting on hydrological connectivity and urban flood mitigation
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The degree of cross-linking of polyacrylic acid affects the fibrogenicity in rat lungs
Published 2025-01-01“…Lactate dehydrogenase (LDH) activity in BALF and heme oxygenase-1 (HO-1) release in lung tissue were higher in the CL0.1% exposure group during the acute phase. …”
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D-mannose-modified nanoliposomes enhance the targeted delivery of ovalbumin to improve its anti-inflammatory, antioxidant, and macrophage polarization effects
Published 2025-01-01“…Furthermore, ROS levels were decreased, SOD and GSH activity was enhanced, the Nrf2/HO-1 pathway was activated, and the compound exhibited strong antioxidant activity. …”
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<i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials
Published 2025-01-01“…The extract exhibited antioxidant properties by scavenging ABTS<sup>•+</sup>, H<sub>2</sub>O<sub>2</sub>, AAPH, and HO<sup>•</sup> radicals. Additionally, it demonstrated antibacterial activity by inhibiting the growth of four strains of <i>Staphylococcus aureus</i>. …”
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