Presynaptic Ionotropic Receptors Controlling and Modulating the Rules for Spike Timing-Dependent Plasticity by Matthijs B. Verhoog, Huibert D. Mansvelder

“…Ionotropic neurotransmitter receptors, such as NMDA receptors and nicotinic acetylcholine receptors, are intimately involved in setting the rules for synaptic strengthening and weakening. …”
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Novel Insights for Systemic Inflammation in Sepsis and Hemorrhage by Bolin Cai, Edwin A. Deitch, Luis Ulloa

“…In seeking potential anti-inflammatory strategies, we reported that ethyl pyruvate and alpha7 nicotinic acetylcholine receptor (alpha7nAChR) agonists effectively restrained cytokine production to provide therapeutic benefits in both experimental sepsis and hemorrhage. …”
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Smoking Hot: the Odalisque’s eroticizing Cigarette by Liesbeth Grotenhuis

“…Hidden in the harem, the painting made the odalisque available for western eyes: lounging, dancing and above all, blatantly smoking. The Orient was “nicotinized”: fumes evoked dreams and hallucinations, as well as steamy sexual suggestions. …”
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One-Pot Synthesis of Novel Furochromone and Oxazocine Derivatives as Promising Antitumor Agents with Their Molecular Docking Studies by Rita M. Borik

“…One-pot efficient synthesis of novel chromone derivatives 4a–h and that of 5a–h were described in a simple method via four-component reaction between furochromone carbaldehyde, amine, isocyanate derivatives, and benzoic acid derivatives or nicotinic acid, respectively. Also, oxazocine derivatives 7a, b were prepared via reaction of visnagine carbaldehyde, ethyl acetoacetate and isocyanate derivatives 2a, b. …”
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Pregnancy Outcome after Varenicline Exposure in the First Trimester by Yusuf Cem Kaplan, Nihal Olgac Dündar, Burcu Kasap, Barıs Karadas

“…To the best of our knowledge this is the first case report describing exposure to varenicline, an α4β2 nicotinic acetylcholine partial receptor agonist used for smoking cessation therapy in pregnancy. …”
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SLC29A1 and SLC29A2 are human nicotinamide cell membrane transporters by Mingyang Chen, Luexiang Yuan, Binxin Chen, Hui Chang, Jun Luo, Hengbin Zhang, Zhongjian Chen, Jiao Kong, Yaodong Yi, Mengru Bai, Minlei Dong, Hui Zhou, Huidi Jiang

“…Transporters for other precursors of NAD+ such as nicotinic acid and nicotinamide mononucleotide (NMN) have been identified, but the cellular transporter of nicotinamide has not been elucidated. …”
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Case report: Successful perioperative intervention with efgartigimod in a patient in myasthenic crisis by Shahar Shelly

“…Single fiber electromyography demonstrated abnormal jitter response in the orbicularis oculi muscle. Nicotinic acetylcholine receptor antibodies were detected in serum. …”
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Potentiometric Multisensory Systems with Novel Ion-Exchange Polymer-Based Sensors for Analysis of Drugs by Olga V. Bobreshova, Anna V. Parshina, Ksenia A. Polumestnaya

“…Such systems were developed for the multicomponent quantitative analysis of lysine monohydrochloride, thiamine chloride and novocaine hydrochloride solutions that contained salts of alkaline and alkaline-earth metals, as well as for mixed solutions of nicotinic acid and pyridoxine hydrochloride. Multivariate methods of analysis were used for sensor calibration and the analysis of the total response of sensor arrays. …”
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Validation of an RPHPTLC-Densitometric Method Using Silica Gel 60 RP18WF254 for Simultaneous Determination of Nicotinamide in Selected Pharmaceutical Formulations by Małgorzata Dołowy, Alina Pyka

“…Developed method is accurate and precise (CV<3%) and may be successfully applied for the quality control of pharmaceutical formulations containing nicotinamide in the presence of its derivatives, such as N,N-diethylnicotinamide, N-methylnicotinamide, and nicotinic acid.…”
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Potential Role of Synaptic Activity to Inhibit LTD Induction in Rat Visual Cortex by Matthew R. Stewart, Hans C. Dringenberg

“…Pairing LFS with stimulation of the brainstem (pedunculopontine) reticular formation resulted in the appearance of faster, more complex activity in V1 and prevented LTD induction, an effect that did not require muscarinic or nicotinic receptors. Reticular stimulation alone (without LFS) had no effect on cortical fPSPs. …”
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A multi-levels analysis to evaluate the toxicity of microplastics on aquatic insects: A case study with damselfly larvae (Ischnura elegans) by Lin Sun, Zhongyan Cheng, Mei Wang, Chao Wei, Haoyu Liu, Yuxia Yang

“…Furthermore, expression levels of some metabolites altered, such as nicotinic acid, fumaric acid, and stearic acid. Meanwhile, the pathways related to oxidative phosphorylation and carbon metabolism were upregulated at the transcriptomic level. …”
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Using Protein Painting Mass Spectrometry to Define Ligand Receptor Interaction Sites for Acetylcholine Binding Protein by Alexandru Graur, Natalie Erickson, Nadine Kabbani

“…Nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion channels expressed in nervous and non-nervous system tissue important for memory, movement, and sensory processes. …”
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The Effects of Urethane on Rat Outer Hair Cells by Mingyu Fu, Mengzi Chen, Xiao Yan, Xueying Yang, Jinfang Xiao, Jie Tang

“…This urethane-induced outward current was blocked by strychnine, an antagonist of the α9 subunit of the nicotinic acetylcholine receptor. Meanwhile, the function of the outer hair cell motor protein, prestin, was not affected. …”
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Potential of germanium-based compounds in coronavirus infection by NAROKHA VIOLETTA, NIZHENKOVSKA IRYNA, KUZNETSOVA OLENA

“…They include germanium carboxylates and citrates, complexes of germanium with resveratrol, daphnetin, mangiferin, chrysin, quercetin, ascorbic and nicotinic acids, amino acids, gamma-lactones, germanium-containing spirulina, yeast and others. …”
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Diversity of Production Techniques and Microbiology of African Cereal-Based Traditional Fermented Beverages by Felix Kwashie Madilo, Angela Parry-Hanson Kunadu, Kwaku Tano-Debrah, Firibu Kwesi Saalia, Unathi Kolanisi

“…Most of these beverages were found to be very rich in proteins, carbohydrates, calories, and B-group vitamins including thiamine, folic acid, riboflavin, and nicotinic acid. This article reviewed the available information, such as processing techniques of African traditional beverages, the raw materials used to producing them, and the microorganisms associated with the production processes.…”
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Genetic and neuro-epigenetic effects of divergent artificial selection for feather pecking behaviour in chickens by Elske N. de Haas, Fábio Pértille, Joergen B. Kjaer, Per Jensen, Carlos Guerrero-Bosagna

“…The largest CNVs found were in RIC3 (gain in HFP) and SH3RF2 (gain in LFP) genes, linked to nicotinic acetylcholine receptor regulation and human oncogenesis, respectively. …”
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Synthesis and characterization of citrate-capped gold nanoparticles and their application in selective detection of creatinine (A kidney biomarker) by Akriti Tirkey, Punuri Jayasekhar Babu

“…UV–Vis spectrophotometric analysis further confirmed the selectivity of the method among different analytes such as ascorbic acid, nicotinic acid, polyvinyl pyrrolidone, glucose, uric acid, and bovine serum albumin. …”
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Antibacterial activity, quality and stability study of creams with new potential silver(I) complexes and in vivo case report by Sovová Simona, Megyesi Štefánia Laca, Mudroňová Dagmar, Mudroň Pavol, Harvanová Jarmila, Rendošová Michaela, Goga Michal, Tkáčiková Ľudmila, Vargová Zuzana

“…The aim of this study was to evaluate the antibacterial activity, quality and stability of creams (at 1 % concentration) prepared with synthesized silver(I) complexes: [Ag(Nam)2]NO3·H2O ( AgNam), [Ag2(HGly)2]n(NO3)2n (AgGly) (Nam – nicotin-amide, Gly – glycine) and silver(I) sulfadiazine (AgSD), which is commercially available. …”
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Evaluating Cholinergic Receptor Expression in Guinea Pig Primary Auditory and Rostral Belt Cortices After Noise Damage Using [H]Scopolamine and [F]Flubatine Autoradiography by Taylor J. Forrest MS, Timothy J. Desmond MS, Mohamad Issa MD, Peter J. H. Scott PhD, Gregory J. Basura MD, PhD

“…We used [ 3 H]scopolamine and [ 18 F]flubatine binding to measure muscarinic acetylcholine receptor (mAChR) and nicotinic acetylcholine receptor (nAChR) expression, respectively, in guinea pig A1 and RB 3 weeks following unilateral, left ear noise exposure, and a temporary threshold shift in hearing. [ 3 H]Scopolamine binding decreased in right A1 and RB (contralateral to noise) compared to sham controls across all cortical layers. [ 18 F]Flubatine binding showed a nonsignificant upward trend in right A1 following noise but only significantly increased in right RB and 2 layers of left RB (ipsilateral to noise). …”
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The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis by Song Hu, Yundong Wang, Hongbing Li

“…Firstly, the vagus nerve senses and regulates local or systemic inflammation by means of the Cholinergic Anti-inflammatory Pathway (CAP) and activation of α7-nicotinic acetylcholine receptors (α7nAChRs); thus, α7nAChRs play important roles for the central nervous system (CNS) to modulate peripheral inflammation; secondly, the activation of muscarinic acetylcholine receptors 1 (M1AChRs) in the forebrain can affect the neurons of the Medullary Visceral Zone (MVZ), the core of CAP, to regulate systemic inflammation and immunity. …”
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