Healthcare-seeking delays and associated factors among immigrant patients with acute ischaemic stroke in Shenzhen: a retrospective observational study by Qingshi Zhao, Changyu Li, Zongbi Wu, Youli Jiang, Yanfeng Li

“…The study investigated sociodemographic, clinical data and stroke-specific scales (modified Rankin Scale, National Institutes of Health Stroke Scale, Glasgow Coma Scale) to identify factors influencing delays.Setting The study was conducted in Shenzhen, a city characterised by a significant immigrant population, providing insights applicable to urban regions with similar demographics.Results Of the 1356 patients studied, 82.6% (n=1120) experienced healthcare-seeking delays, with a median delay of 12.67 hours (IQR: 3.5–28.8). …”
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Outcomes and safety of mechanical thrombectomy, alteplase, and conventional medical care in the treatment of acute M2 segment middle cerebral artery occlusion: a comparative study by Eman M. Khedr, Ahmed Elbassiouny, Mahmoud Nageeb, Ahmed Aly, Khalid O. Mohamed, Nourelhoda A. Haridy

“…This prospective longitudinal intervention study compared the outcomes and safety of MT, rTPA, and CMT in M2 occlusion AIS patients. National Institutes of Health Stroke Scale (NIHSS), modified Rankin scale (mRS), and recanalization rate assessed outcomes. …”
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Effect of a Vibration System on Pain Reduction during Injection of Dental Anesthesia in Children: A Randomized Clinical Trial by Muhanad AlHareky, Jehan AlHumaid, Sumit Bedi, Maha El Tantawi, Mazin AlGahtani, Yousef AlYousef

“…This study was registered with clinical trial registry of the United States National Institutes of Health (NIH) at ClinicalTrials.gov (NCT03953001).…”
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Industry of employment and occupational class in relation to cardiovascular health by race/ethnicity, sex/gender, age and income among adults in the USA: a cross-sectional study by Symielle A Gaston, Chandra L Jackson, Jamie A Murkey, Dana M Alhasan, W Braxton Jackson

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Chronic endothelial inflammation in PWH leads to reduced circulating megakaryocyte progenitor cells by Tong Li, Colleen Hadigan, Jaeil Ahn, Chinmayee Mehta, Makheni Jean Pierre, Danial Mahmood, Metin Ozdemirli, Cooper James, Princy Kumar, Marta Catalfamo

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A Pilot Proteomic Analysis of Huntington’s Disease by Functional Capacity by Andrew McGarry, Ruin Moaddel

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G-Filtering Nonstationary Time Series by Mengyuan Xu, Krista B. Cohlmia, Wayne A. Woodward, Henry L. Gray

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Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes by Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Licia Luna, Aneri Balar, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Vaibhav Vagal, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Kambiz Nael, Gregory W. Albers, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Argye E. Hillis, Raf Llinas, Vivek Yedavalli

“…This study investigates the association between PVT and percent change on the National Institutes of Health Stroke Scale (NIHSS) among AIS‐LVO patients who have undergone successful reperfusion. …”
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Therapeutic Effect of Mirror Therapy Combined with Conventional Speech Training on Subcortical Aphasia after Acute Cerebral Infarction by Qingmei CHEN, Xiuying CAI, Jun KE, Dan SHEN, Keke FAN, Weixin YANG, Li LI, Qi FANG

“…The aphasia quotient (AQ) in the western aphasia test, National Institutes of Health Stroke Scale (NIHSS) and the Modified Rankin Scale (mRS) were assessed before treatment, and at the third and 12th week of disease. …”
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Characteristics Associated with Successful Residency Match in General Surgery by Reagan A. Collins, BA, Kaitlyn Nimmer, BA, Salma A. Sheriff, BS, Tania K. Arora, MD, Anai N. Kothari, MD, MS, Carrie Cunningham, MD, MPH, Callisia N. Clarke, MD, MS

“…Matched versus unmatched applicants had higher step 1 scores (US: 236 vs 218, P = 0.005; independent: 237 vs 228, P = 0.001), higher step 2 scores (US: 248 vs 232, P = 0.006; independent: 245 vs 234, P < 0.001), more likely to belong to alpha omega alpha (US: 17.1% vs 1.6%, P = 0.002) or to attend a top 40 National Institutes of Health-funded school (US: 31.0% vs 19.4%, P = 0.002) compared to unmatched applicants. …”
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Prognostic analysis of endovascular mechanical thrombectomy in stroke patients with acute internal carotid artery obstruction based on circle of Willis variation by Tianlun Qiu, Huagang Luo, Wuqiao Bao

“…EVMT was initiated upon admission, and baseline data including demographic characteristics, vascular risk factors, angiographic features, initial National Institutes of Health Stroke Scale (NIHSS) scores, Alberta Stroke Program Early CT Score (ASPECT), and etiology classification were compared across these four grades. …”
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Infarct Growth in Patients with Emergent Large Vessel Occlusion Stroke Transferred for Endovascular Thrombectomy by Xiangjun Xu, Yujuan Zhu, Yapeng Guo, Hao Wang, Junfeng Xu, Ke Yang, Liang Ge, Yi Sun, Xianhui Ding, Qian Yang, Chuyuan Ni, Xianjun Huang

“…Results We included 309 patients: median age 72 years (IQR 65–77); median National Institutes of Health Stroke Scale (NIHSS) 14 (IQR 11–18). …”
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Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design by Haiying Qin, Nirali N Shah, Terry J Fry, Lila Yang, John A Chukinas, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Sarah K Tasian, Naomi A Taylor

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Proteomic and serologic assessments of responses to mRNA-1273 and BNT162b2 vaccines in human recipient sera by Thomas E. Hickey, Uma Mudunuri, Heidi A. Hempel, Troy J. Kemp, Nancy V. Roche, Keyur Talsania, Brian A. Sellers, James M. Cherry, Ligia A. Pinto

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Aneurysmal Subarachnoid Hemorrhage Models: Do They Need a Fix? by Fatima A. Sehba, Ryszard M. Pluta

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TLR Specific Immune Responses against Helminth Infections by Sivaprakasam Rajasekaran, Rajamanickam Anuradha, Ramalingam Bethunaickan

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Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels by Thomas M. Snyder, Rachel M. Gittelman, Mark Klinger, Damon H. May, Edward J. Osborne, Ruth Taniguchi, H. Jabran Zahid, Ian M. Kaplan, Jennifer N. Dines, Matthew T. Noakes, Ravi Pandya, Xiaoyu Chen, Summer Elasady, Emily Svejnoha, Peter Ebert, Mitchell W. Pesesky, Patricia De Almeida, Hope O’Donnell, Quinn DeGottardi, Gladys Keitany, Jennifer Lu, Allen Vong, Rebecca Elyanow, Paul Fields, Hussein Al-Asadi, Julia Greissl, Lance Baldo, Simona Semprini, Claudio Cerchione, Fabio Nicolini, Massimiliano Mazza, Ottavia M. Delmonte, Kerry Dobbs, Rocio Laguna-Goya, Gonzalo Carreño-Tarragona, Santiago Barrio, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Camillo Rossi, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angio, Paolo Bonfanti, Miranda F. Tompkins, Camille Alba, Clifton Dalgard, Vittorio Sambri, Giovanni Martinelli, Jason D. Goldman, Jason D. Goldman, James R. Heath, Helen C. Su, Luigi D. Notarangelo, Estela Paz-Artal, Joaquin Martinez-Lopez, Bryan Howie, Jonathan M. Carlson, Harlan S. Robins

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Safety and efficacy of intravenous thrombolysis: a systematic review and meta-analysis of 93,057 minor stroke patients by Mostafa Hossam El Din Moawad, Talal Salem, Anas Alaaeldin, Youssef Elaraby, Peter D. Awad, Amr Ahmed Khalifa, Ahmed El Naggar, Khaled Ashraf Mohamed, Mohamed Elhalal, Mostafa Badr, Ramy Abdelnaby

“…Abstract Background The definition of minor ischemic stroke (MIS) is a topic of debate, however, the most accepted definition is a stroke with National Institutes of Health Stroke Scale (NIHSS) ≤ 5. Intravenous thrombolysis (IVT) is a crucial treatment option for acute ischemic stroke (AIS) including: alteplase, recombinant human tissue-type plasminogen activator (r-tPA), and the recently approved tenecteplase. …”
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Comparative efficacy of neuroprotective agents for improving neurological function and prognosis in acute ischemic stroke: a network meta-analysis by Yuchen Wang, Yuchen Wang, Mengqi Li, Mengqi Li, Yuye Jiang, Yuye Jiang, Qiuhong Ji

“…Outcomes included 90-day modified Rankin Scale (90d-mRS), change of National Institutes of Health Stroke Scale score from baseline to 90-day/14-day/7-day (90d/14d/7d-NIHSS) and 90-day/14-day Barthel Index (90d/14d-BI). …”
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Cerebral blood flow change with fluid resuscitation in acute ischemic stroke by Joseph Miller, John Aidan Moloney, Noah Elagamy, Jacob Tuttle, Sam Tirgari, Sean Calo, Richard Thompson, Bashar Nahab, Christopher Lewandowski, Phillip Levy

“…Patients had a National Institutes of Health Stroke Scale (NIHSS) score of 3 or higher. …”
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